Patents by Inventor Tom Beetz

Tom Beetz has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Pentasaccharides and tetrasaccharides having anti-thrombotic activity
    Patent number: 4841041
    Abstract: The present invention is dealing with new pentasaccharides of the formula I: ##STR1## These pentasaccharides have anti-thrombotic activity and especially they possess potent anti-Xa activity, inactivate thrombin via HC-II, but do not inactivate thrombin via AT-III.The invention also refers to new tetrasaccharides which may be used as intermediates in the synthesis of the above pentasaccharides.
    Type: Grant
    Filed: July 12, 1988
    Date of Patent: June 20, 1989
    Assignees: Akzo N.V., Sanofi S.A.
    Inventors: Constant A. A. van Boeckel, Tom Beetz, Maurice Petitou
  • Disaccharide and trisaccharide derivatives of the "Lipid A" type
    Patent number: 4719202
    Abstract: The present invention is dealing with certain disaccharide or trisaccharide derivatives of the lipid A type, which have interesting immuno-modulating, more particularly immuno-stimulating properties.
    Type: Grant
    Filed: February 11, 1986
    Date of Patent: January 12, 1988
    Assignee: Akzo N.V.
    Inventors: Constant A. A. van Boeckel, Tom Beetz
  • Cycloalkane-indene-carboximidamide derivatives
    Patent number: 4661522
    Abstract: The present invention is dealing with cycloalkane-indene-carboximidamide derivatives having the general formula: ##STR1## wherein Rx together with either Ry.sub.1 or Ry.sub.2 represent the moiety ##STR2## (the other Ry being hydrogen), n represents the number 1, 2 or 3,R represents hydrogen or a (1-4 C)-alkyl group,R.sub.1 represents hydrogen, (1-4 C)-alkyl, hydroxyl, (1-4 C)-alkoxy or an amino group which is unsubstituted or substituted by (1-4 C)-alkyl andR.sub.2 is hydrogen, hydroxyl or (1-4 C)-alkyl,as well as the pharmaceutically acceptable salts thereof, with powerful blood platelet aggregation-inhibiting activity.
    Type: Grant
    Filed: May 15, 1985
    Date of Patent: April 28, 1987
    Assignee: Akzo N.V.
    Inventor: Tom Beetz