Patents by Inventor Tom Boonefaes

Tom Boonefaes has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Buffer-and-salt-content-independent UV-VIS spectroscopic characterisation of sample DNA and/or RNA content using reference samples having distinct buffer and/or salt content
    Patent number: 10488330
    Abstract: A method is described for characterising a sample comprising at least DNA and/or RNA. The method comprises obtaining a UV-VIS spectroscopic measurement of the sample comprising at least DNA and/or RNA, deriving an absorption parameter based on the UV-VIS spectroscopic measurement, and determining a DNA and/or RNA quantification present in the sample. Determining a DNA and/or RNA quantification thereby comprises taking into account a buffer and/or salt effect on the UV-VIS spectroscopic measurement irrespective of the actual buffer and salt content of the sample, based on said derived absorption parameter and reference spectral data including spectral information for buffer and/or salt effects.
    Type: Grant
    Filed: August 30, 2013
    Date of Patent: November 26, 2019
    Assignee: TRINEAN NV
    Inventor: Tom Boonefaes
  • DNA and/or RNA determination from UV-VIS spectrophotometer data
    Patent number: 10126233
    Abstract: A method for analyzing UV-VIS spectrophotometer data of a sample comprising at DNA and/or RNA is described. The method comprises receiving UV-VIS spectrophotometer data, fitting the UV-VIS spectrometer data taking into account at least one spectrum representative for a base pair being any of more of adenine-thymine (AT) or guanine-cytosine (GC) or adenine-uracil, and deriving from the fitting a quantification of an amount of DNA and/or RNA.
    Type: Grant
    Filed: February 29, 2012
    Date of Patent: November 13, 2018
    Assignee: UNCHAINED LABS
    Inventor: Tom Boonefaes
  • OPTICAL CHARACTERISATION OF DNA AND/OR RNA
    Publication number: 20150226664
    Abstract: A method is described for characterising a sample comprising at least DNA and/or RNA. The method comprises obtaining a UV-VIS spectroscopic measurement of the sample comprising at least DNA and/or RNA, deriving an absorption parameter based on the UV-VIS spectroscopic measurement, and determining a DNA and/or RNA quantification present in the sample. Determining a DNA and/or RNA quantification thereby comprises taking into account a buffer and/or salt effect on the UV-VIS spectroscopic measurement irrespective of the actual buffer and salt content of the sample, based on said derived absorption parameter and reference spectral data including spectral information for buffer and/or salt effects.
    Type: Application
    Filed: August 30, 2013
    Publication date: August 13, 2015
    Inventor: Tom Boonefaes
  • DNA AND/OR RNA DETERMINATION FROM UV-VIS SPECTROPHOTOMETER DATA
    Publication number: 20130332084
    Abstract: A method for analyzing UV-VIS spectrophotometer data of a sample comprising at DNA and/or RNA is described. The method comprises receiving UV-VIS spectrophotometer data, fitting the UV-VIS spectrometer data taking into account at least one spectrum representative for a base pair being any of more of adenine-thymine (AT) or guanine-cytosine (GC) or adenine-uracil, and deriving from the fitting a quantification of an amount of DNA and/or RNA.
    Type: Application
    Filed: February 29, 2012
    Publication date: December 12, 2013
    Inventor: Tom Boonefaes