Abstract: Infection by SARS-CoV-2 is impacting human subjects in their respiratory system and in some cases, their central nervous system (CNS). The virus is hurting certain groups of people more than others, such as the elderly and those with other pre-existing illnesses. Both groups are believed to have lower levels of the antioxidant, glutathione. By delivery of N-acetyl cysteine (NAC) to increase glutathione levels, the present methods reduce the severity of the virus and its symptoms concentrating on the brain and the lungs. NAC may also prevent mild COVID-19 cases from becoming severe. NAC, whether delivered intranasally, inhaled through the mouth, orally or other ways may act as a therapeutic for this virus.