Patents by Inventor Tom Gertrudis Hubertus KEULERS

Tom Gertrudis Hubertus KEULERS has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHOD FOR DETERMINING THE LEVEL OF HYPOXIA IN A TUMOR
    Publication number: 20170176445
    Abstract: The invention is in the field of medicine and molecular therapeutics. The invention provides means and measures for diagnosis and treatment, in particular for diagnosis and treatment of tumors, more in particular for determining the level of hypoxia in a tumor and for reducing the risk of metastasis of a tumor in a subject. The invention comprises a method wherein a level of exosome-associated GABARAPL1 is determined in a bodily fluid of the subject and wherein an elevated level of exosome-associated GABARAPL1 is indicative of an increased level of hypoxia of the tumor. The invention also comprises an antibody directed against GABARAPL1 for use in the treatment or prevention of cancer.
    Type: Application
    Filed: February 11, 2015
    Publication date: June 22, 2017
    Applicants: Universiteit Maastricht, Academisch Ziekenhuis Maastricht
    Inventors: Kasper Mathias Antoon ROUSCHOP, Tom Gertrudis Hubertus KEULERS