Abstract: The present disclosure relates to the field of molecular biology and more specifically to methods for detecting anti-carbamylated protein (anti-CarP) antibodies in the serum of rheumatoid arthritis (RA) patients.

Abstract: The present disclosure relates to the field of molecular biology and more specifically to methods for detecting anti-carbamylated protein (anti-CarP) antibodies in the serum of rheumatoid arthritis (RA) patients.

Abstract: The present disclosure relates to the field of molecular biology and more specifically to methods for detecting anti-carbamylated protein (anti-CarP) antibodies in the serum of rheumatoid arthritis (RA) patients.

Abstract: Methods for predicting the likelihood of development of rheumatoid arthritis for individuals that present with recent-onset undifferentiated arthritis. The methods are based on the determination of a set of clinical parameter values and determining a predicted risk for developing rheumatoid arthritis by correlating the parameter values with predefined risk values associated with ranges of parameter values. Parameters values that are decisive for the risk for developing rheumatoid arthritis may include serum levels of C-reactive protein, Rheumatoid factors, anti-CCP antibodies, as well as age, gender, localization of the joint complaints, length of morning stiffness, and number of tender and/or swollen joints. The method may be performed by a computer. The invention further relates to a computer, a sample analyser and a computer program product for performing the method and a data carrier with the computer program product.

Abstract: The invention relates to the use of gene therapy in the treatment of aseptic loosening of orthopaedic prostheses and discloses methods of refixing such prostheses without open revision surgery. In particular, it provides adenoviral vectors and prodrugs for simultaneous, separate or sequential use in the destruction of interface tissue allowing subsequent recementing of loose prostheses in a minimally invasive manner.

Abstract: A process for upgrading a hydrocarbonaceous feedstock which process included separating the feedstock in the presence of hydrogen at elevated temperature and a partial hydrogen pressure greater than 50 bar into a high boiling fraction and a low boiling fraction and subjecting at least part of the low boiling fraction substantially boiling in the gasoline range to a hydrotreating step under substantially the same conditions as prevailing in the separation step, and recovering from the hydrotreating step a product substantially boiling in the gasoline range and being of improved quality.

Abstract: Process for the preparation of a zeolitic catalyst which comprises treating a zeolite of the Y-type having an alkali oxide/aluminum oxide molar ratio of at most 0.13 with a solution of a multi-valent metal salt having a cationic radius between 0.6 and 1.0 .ANG. and combining the ion-exchanged zeolite without a calcination step with a hydrogenation component of a Group VIII and/or Group VI(b) metal.

Abstract: A process for converting hydrocarbon oils into products of low average molecular weight and lower average boiling point comprising contacting a hydrocarbon oil at elevated temperature and pressure in the presence of hydrogen with a catalyst comprising a modified Y zeolite having a unit cell size below 24.45 .ANG., a degree of crystallinity which is at least retained at increasing SiO.sub.2 /Al.sub.2 O.sub.3 molar ratios, a water adsorption capacity (at 25.degree. C. and a p/p.sub.o value of 0.2) of at least 8% by weight of modified zeolite and a pore volume of at least 0.25 ml/g wherein between 10% and 60% of the total pore volume is made up of pores having a diameter of at least 8 nm, an amorphous cracking component, a binder and at least one hydrogenation component of a Group VI metal and/or at least one hydrogenation component of a Group VIII metal. The invention also relates to catalyst compositions suitable for use in said process.

Abstract: Composition of matter suitable as a catalyst (base) in hydroprocessing comprising a crystalline aluminosilicate zeolite and a binder wherein the crystalline aluminosilicate comprises a modified Y zeolite having a unit cell size below 24.35 .ANG., a degree of crystallinity which is at least retained at increasing SiO.sub.2 /Al.sub.2 O.sub.3 molar ratios, a water adsorption capacity (at 25.degree. C. and a p/p.sub.o value of 0.2) of at least 8% by weight of modified zeolite and a pore volume of at least 0.25 ml/g wherein between 10% and 60% of the total pore volume is made up of pores having a diameter of at least 8 nm. The invention also relates to hydroconversion catalysts and processes based on said compositions of matter.

Abstract: The invention relates to a process for the preparation of a shapable dough which comprises mixing and kneading a particulate silica-alumina with water and with an alkanolamine or ammonia to obtain a mixture having a total solids content of from 25 to 60% by weight, the alkanolamine or ammonia being present in an amount of from 0.5 to 20% by weight on the total solids content of the mixture, to a shapable dough obtained by this process, to the preparation of silica-alumina extrudates therefrom and to their use as catalyst carriers in hydrocarbon conversion or hydrocarbon synthesis reactions.

Abstract: A process for converting hydrocarbon oils into products of low average molecular weight and lower average boiling point comprising contacting a hydrocarbon oil at elevated temperature and pressure in the presence of hydrogen with a catalyst comprising a modified Y zeolite having a unit cell size below 24.45 .ANG., a degree of crystallinity which is at least retained at increasing SiO.sub.2 /Al.sub.2 O.sub.3 molar ratios, a water adsorption capacity (at 25.degree. C. and p/p.sub.o value of 0.2) of at least 8% by weight of modified zeolite and a pore volume of at least 0.25 ml/g wherein between 10% and 60% of the total pore volume is made up of pores having a diameter of at least 8 nm, an amorphous cracking component, a binder and at least one hydrogenation component of a Group VI metal and/or at least one hydrogenation component of a Group VIII metal. The invention also relates to catalyst compositions suitable for use in said process.

Abstract: Composition of matter suitable as a catalyst (base) in hydroprocessing comprising a crystalline aluminosilicate zeolite and a binder wherein the crystalline aluminosilicate comprises a modified Y zeolite having a unit cell size below 24.35 .ANG., a degree of crystallinity which is at least retained at increasing SiO.sub.2 /Al.sub.2 O.sub.3 molar ratios, a water adsorption capacity (at 25.degree. C. and a p/p.sub.o value of 0.2) of at least 8% by weight of modified zeolite and a pore volume of at least 0.25 ml/g wherein between 10% and 60% of the total pore volume is made up of pores having a diameter of at least 8 nm. The invention also relates to hydroconversion catalysts and processes based on said compositions of matter.

Abstract: A process is disclosed for the catalytic dewaxing of a hydrocarbon oil by contacting said oil at catalytic dewaxing conditions with a catalyst comprising a crystalline aluminum silicate which has the following composition in terms of the molar ratios of the oxides:(0.9+0.2)Z.sub.p O.sub.q :Al.sub.2 O.sub.3 :xSiO.sub.2 : yH.sub.2 Owherein Z is at least one cation, p and q are each at least one and satisfy the electroneutrality of Z.sub.p O.sub.q, x is at least 10 and y/x is 0-25, and which crystalline aluminum silicate has a defined characteristic X-ray diffraction pattern as set forth in Table A.

Abstract: A process of manufacture of a crystalline aluminum silicate is disclosed wherein the aqueous forming solution has augmented thereto both a pyridine compound and a quaternary ammonium hydroxide. The process derives a novel crystalline aluminum silicate composition of matter.

Abstract: A process of manufacture of a crystalline aluminum silicate is disclosed wherein the aqueous forming solution has augmented thereto both a pyridine compound and a quaternary ammonium hydroxide. The process derives a novel crystalline aluminum silicate composition of matter.