Abstract: In an analytical instrument having a radiation detector, such as an electron microscope with an X-ray detector, a thermoelectric element (such as one or more Peltier junctions) is driven by a cooling power supply to cool the detector and thereby decrease measurement noise. Oil condensates and ice can then form on the detector owing to residual water vapor and vacuum pump oil in the analysis chamber, and these contaminants can interfere with measurement accuracy. To assist in reducing this problem, the thermoelectric element can be powered in the reverse of its cooling mode, thereby heating the detector and evaporating the contaminants. After the detector is cleared of contaminants, it may again be cooled and measurements may resume. Preferably, the thermoelectric element is heated by a power supply separate from the one that provides the cooling power, though it can also be possible to utilize a single power supply to provide both heating and cooling modes.

Abstract: An improved clamping mechanism for clamping a dock support frame having a hollow recess and a U-shaped cut-out to a vertical support member has an anvil clamping member comprised of extruded aluminum. The anvil clamping member has an arc-shaped clamping surface and is fixedly disposed inside the hollow recess in the support frame. A hammer clamping member comprised of extruded aluminum and having a corresponding arc-shaped clamping surface is adjustably attached to the anvil clamping member such that the vertical support member can pass between the hammer clamping member and the anvil clamping member and through the U-shaped cut-out of the support frame.

Abstract: A lighting accessory stem using fiberoptic illumination is provided. In certain embodiments, the lighting accessory system is combinable with a hand tool, for example a forceps, to illuminate the grasping tips of the tool. The lighting accessory system provides an illuminable tool whereby an object may be illuminated and grasped while being illuminated without obstruction by the illumination means. In certain embodiments, the lighting accessory system may be used for medical or surgical tools.

Abstract: A lighting accessory system using fiberoptic illumination is provided. In certain embodiments, the lighting accessory system is combinable with a hand tool, for example a forceps, to illuminate the grasping tips of the tool. The lighting accessory system provides an illuminable tool whereby an object may be illuminated and grasped while being illuminated without obstruction by the illumination means. In certain embodiments, the lighting accessory system may be used for medical or surgical tools.

Abstract: A compound having the general formula and methods of using such compounds for the treatment of diseases and pharmaceutical composition comprising such compounds.

Abstract: The present invention relates to a lighting accessory system using fiberoptic illumination. In certain embodiments, the lighting accessory system of the present invention is combinable with a hand tool, for example a forceps, to illuminate the grasping tips of the tool. The lighting accessory system provides an illuminable tool whereby an object may be illuminated and grasped while being illuminated without obstruction by the illumination means. In certain embodiments, the lighting accessory system may be used for medical or surgical tools.

Abstract: Compounds of formula I ##STR1## wherein Q.sup.1, Q.sup.2, Q.sup.3, and Q.sup.4 have any of the meanings given in the specification, their N-oxides, and their pharmaceutically acceptable salts are nonpeptide antagonists of neurokinin A and useful for the treatment of asthma, etc. Also disclosed are pharmaceutical compositions, processes for preparing the compounds of formula I and intermediates.

Abstract: A yarn monitor for an automatic cross winding and yarn assembly machine in which at least two yarns are wound in parallel from two run-off bobbins onto a cross bobbin. The monitor includes a drive roller for driving round the cross bobbin, a driver for rotating the drive roller in two opposite directions and a wind-off eye for leading the two yarns to the cross bobbin. A yarn guide is provided for axially guiding the yarns on the cross bobbin, the yarn guide being installed between the cross bobbin and the wind-off eye for controlling and correcting the position of the two yarns with respect to one another. The yarn guide comprises a cutting apparatus for cutting at least one of the yarns and a driver for the cutting apparatus. A yarn guide is provided for guiding the yarns co-operating with the cutting apparatus. Sensors are provided for detecting the yarns in the yarn guide and for controlling the cutting apparatus.

Abstract: The machine comprises a yarn guide for axially guiding the yarn on the receiving cross bobbin, for each wound off yarn at least one yarn watcher, a cutting device for cutting through the yarn, a yarn tensioner and a joining device for joining yarn ends, where a yarn monitor with a method of controlling is provided for controlling and correcting the assembled yarn bundle and rewinding the cross bobbin, a gripper device for gripping the yarn ends on the cross bobbin, a gripper device for inserting each yarn into the joining device, a gripper device for receiving and holding the yarn ends, a wind-off eye for the shared winding-off of the assembled yarns installed above the yarn joining devices, and a method of control for these devices, where the method of control are separately controlled.

Abstract: Compounds of formula I ##STR1## wherein Q.sup.1, Q.sup.2, Q.sup.3, and Q.sup.4 have any of the meanings given in the specification, their N-oxides, and their pharmaceutically acceptable salts are nonpeptide antagonists of neurokinin A and useful for the treatment of asthma, etc. Also disclosed are pharmaceutical compositions, processes for preparing the compounds of formula I and intermediates.

Abstract: Compounds of formula I, and pharmaceutically acceptable salts thereof, useful in the treatment of neuropsychiatric disorders such as psychoses; pharmaceutical compositions comprising a compound of formula I and a pharmaceutically acceptable diluent or carrier; and methods of treating neuropsychiatric disorders comprising administering to a mammal (including man) in need of such treatment an effective amount of a compound of formula I, or a pharmaceutically acceptable salt thereof.

Abstract: Compounds of formula I ##STR1## wherein Q.sup.1, Q.sup.2, Q.sup.3, and Q.sup.4 have any of the meanings given in the specification, their N-oxides, and their pharmaceutically acceptable salts are nonpeptide antagonists of neurokinin A and useful for the treatment of asthma, etc. Also disclosed are pharmaceutical compositions, processes for preparing the compounds of formula I and intermediates.

Abstract: Compounds of formula I or I', ##STR1## wherein X and Y are independently selected from hydrogen, halo, and (1-6C)alkoxy;R.sup.1 is selected from(A) (1-6C)alkyl;(B) phenyl and naphthyl or substituted versions thereof;(C) phenyl(1-3C)alkyl and naphthyl(1-3C)alkyl;(D) five- and six-membered heteroaryl rings;(E) heteroaryl(1-3C)alkyl and pharmaceutically acceptable salts thereof, useful in the treatment of neuropsychiatric disorders such as psychoses; pharmaceutical compositions comprising a compound of formula I or I' and a pharmaceutically acceptable diluent or carrier; and methods of treating neuropsychiatric disorders comprising administering to a mammal (including man) in need of such treatment an effective amount of a compound of formula I or I', or a pharmaceutically acceptable salt thereof are claimed. The invention also relates to novel processes for producing enantiomeric methanoanthracenyl sulfoxides.

Abstract: The present invention concerns the novel use of aryl substituted heterocycles of formula I, set out below, which antagonize the pharmacological actions of one of ent endogenous neuropeptide tachykinins an the neurokinin 2 (NK2) receptor making them useful whenever such antagonism is desired, such as in the treatment of asthma and related conditions. The invention also provides pharmaceutical compositions containing the aryl substituted heterocycles for use in such treatment. Certain novel aryl substituted heterocycles of formula I and novel intermediates for their manufacture are also provided.