Patents by Inventor Tom McCollum

Tom McCollum has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 9971138
    Abstract: A system, apparatus and method for using modular microscopes is disclosed. Connecting the housings of the individual microscope modules provide the structural framework of the modular microscope. Furthermore, the modular microscope can include specialized software, the distribution and use of which can be controlled using security keys or identifiers stored on one or more of the microscope modules. The security keys and identifiers can be based on calibration data associated with the physical, electrical, or optical properties of one of more of the modules. The illumination modules disclosed provide for selectable wavelengths and controllable levels of output illumination for both bright field and dark field illumination.
    Type: Grant
    Filed: April 25, 2014
    Date of Patent: May 15, 2018
    Assignee: Bio-Rad Laboratories, Inc.
    Inventors: Michael Griffin, Daniel Yue Man Chu, Tom McCollum
  • Patent number: 9850517
    Abstract: Biological cells in a liquid suspension are counted in an automated cell counter that focuses an image of the suspension on a digital imaging sensor that contains at least 4,000,000 pixels each having an area of 2×2 ?m or less and that images a field of view of at least 3 mm2. The sensor enables the counter to compress the optical components into an optical path of less than 20 cm in height when arranged vertically with no changes in direction of the optical path as a whole, and the entire instrument has a footprint of less than 300 cm2. Activation of the light source, automated focusing of the sensor image, and digital cell counting are all initiated by the simple insertion of the sample holder into the instrument. The suspension is placed in a sample chamber in the form of a slide that is shaped to ensure proper orientation of the slide in the cell counter.
    Type: Grant
    Filed: September 27, 2013
    Date of Patent: December 26, 2017
    Assignee: Bio-Rad Laboratories, Inc.
    Inventors: Tom McCollum, Paul Patt, Frank Shen, Daniel Y. Chu, Don Flory, Mike Griffin, Xin Heng, Eli Hefner
  • Patent number: 9329127
    Abstract: In a scanning system for the detection and discrimination of a plurality of targets in each of a plurality of samples, one or more multiband fluorescence detection channels each of which contains a single multiband emission filter and a single detector replaces multiple detection components in scanning heads of the prior art. In certain embodiments, a single multi-emitter light source is used as well, to illuminate each sample with excitation light at a variety of distinct wavelengths in succession.
    Type: Grant
    Filed: April 17, 2012
    Date of Patent: May 3, 2016
    Assignee: Bio-Rad Laboratories, Inc.
    Inventor: Tom McCollum
  • Publication number: 20140327349
    Abstract: A drawer apparatus having a drawer chassis and a drawer adapted to move relative to the drawer chassis from a closed position to an open position. The drawer has first and second lateral sides. A lid assembly is moveable from an upward position to a downward position relative to the drawer chassis. The lid assembly has first and second roller members. A first lever arm is rotatable about a first pivot on the first lateral side. The first lever arm has a first surface for moveably engaging with the first roller member. A second lever arm is rotatable about a second pivot on the second lateral side. The second lever arm has a second surface for moveably engaging with the second roller. A handle connects the first and second lever arms. The handle is adapted to move the first and second lever arms respectively about the first and second pivots to move the lid assembly from the downward position to the upward position.
    Type: Application
    Filed: April 30, 2014
    Publication date: November 6, 2014
    Applicant: BIO-RAD LABORATORIES, INC.
    Inventors: Jeffry M. Ceremony, Tom McCollum
  • Publication number: 20140293412
    Abstract: A system, apparatus and method for using modular microscopes is disclosed. Connecting the housings of the individual microscope modules provide the structural framework of the modular microscope. Furthermore, the modular microscope can include specialized software, the distribution and use of which can be controlled using security keys or identifiers stored on one or more of the microscope modules. The security keys and identifiers can be based on calibration data associated with the physical, electrical, or optical properties of one of more of the modules. The illumination modules disclosed provide for selectable wavelengths and controllable levels of output illumination for both bright field and dark field illumination.
    Type: Application
    Filed: April 25, 2014
    Publication date: October 2, 2014
    Applicant: Bio-Rad Laboratories, Inc.
    Inventors: Michael Griffin, Daniel Yue Man Chu, Tom McCollum
  • Patent number: 8711474
    Abstract: A system, apparatus and method for using modular microscopes is disclosed. Connecting the housings of the individual microscope modules provide the structural framework of the modular microscope. Furthermore, the modular microscope can include specialized software, the distribution and use of which can be controlled using security keys or identifiers stored on one or more of the microscope modules. The security keys and identifiers can be based on calibration data associated with the physical, electrical, or optical properties of one of more of the modules. The illumination modules disclosed provide for selectable wavelengths and controllable levels of output illumination for both bright field and dark field illumination.
    Type: Grant
    Filed: June 28, 2010
    Date of Patent: April 29, 2014
    Assignee: Bio-Rad Laboratories, Inc.
    Inventors: Michael Griffin, Daniel Yue Man Chu, Tom McCollum
  • Publication number: 20140024107
    Abstract: Biological cells in a liquid suspension are counted in an automated cell counter that focuses an image of the suspension on a digital imaging sensor that contains at least 4,000000 pixels each having an area of 2×2 ?m or less and that images a field of view of at least 3 mm2. The sensor enables the counter to compress the optical components into an optical path of less than 20 cm in height when arranged vertically with no changes in direction of the optical path as a whole, and the entire instrument has a footprint of less than 300 cm2. Activation of the light source, automated focusing of the sensor image, and digital cell counting are all initiated by the simple insertion of the sample holder into the instrument. The suspension is placed in a sample chamber in the form of a slide that is shaped to ensure proper orientation of the slide in the cell counter.
    Type: Application
    Filed: September 27, 2013
    Publication date: January 23, 2014
    Applicant: Bio-Rad Laboratories, Inc.
    Inventors: Tom McCOLLUM, Paul PATT, Frank SHEN, Daniel Y. CHU, Don FLORY, Mike GRIFFIN, Xin HENG, Eli HEFNER
  • Patent number: 8570370
    Abstract: Biological cells in a liquid suspension are counted in an automated cell counter that focuses an image of the suspension on a digital imaging sensor that contains at least 4,000,000 pixels each having an area of 2×2 ?m or less and that images a field of view of at least 3 mm2. The sensor enables the counter to compress the optical components into an optical path of less than 20 cm in height when arranged vertically with no changes in direction of the optical path as a whole, and the entire instrument has a footprint of less than 300 cm2. Activation of the light source, automated focusing of the sensor image, and digital cell counting are all initiated by the simple insertion of the sample holder into the instrument. The suspension is placed in a sample chamber in the form of a slide that is shaped to ensure proper orientation of the slide in the cell counter.
    Type: Grant
    Filed: August 27, 2010
    Date of Patent: October 29, 2013
    Assignee: Bio-Rad Laboratories, Inc.
    Inventors: Tom McCollum, Paul Patt, Frank Shen, Daniel Y. Chu, Don Flory, Mike Griffin, Xin Heng, Eli Hefner
  • Publication number: 20130102481
    Abstract: In a scanning system for the detection and discrimination of a plurality of targets in each of a plurality of samples, one or more multiband fluorescence detection channels each of which contains a single multiband emission filter and a single detector replaces multiple detection components in scanning heads of the prior art. In certain embodiments, a single multi-emitter light source is used as well, to illuminate each sample with excitation light at a variety of distinct wavelengths in succession.
    Type: Application
    Filed: April 17, 2012
    Publication date: April 25, 2013
    Applicant: BIO-RAD LABORATORIES, INC. (002558)
    Inventor: Tom McCollum
  • Publication number: 20110211058
    Abstract: Biological cells in a liquid suspension are counted in an automated cell counter that focuses an image of the suspension on a digital imaging sensor that contains at least 4,000,000 pixels each having an area of 2×2 ?m or less and that images a field of view of at least 3 mm2. The sensor enables the counter to compress the optical components into an optical path of less than 20 cm in height when arranged vertically with no changes in direction of the optical path as a whole, and the entire instrument has a footprint of less than 300 cm2. Activation of the light source, automated focusing of the sensor image, and digital cell counting are all initiated by the simple insertion of the sample holder into the instrument. The suspension is placed in a sample chamber in the form of a slide that is shaped to ensure proper orientation of the slide in the cell counter.
    Type: Application
    Filed: August 27, 2010
    Publication date: September 1, 2011
    Applicant: BIO-RAD LABORATORIES, INC.
    Inventors: Tom McCollum, Paul Patt, Frank Shen, Daniel Y. Chu, Don Flory, Mike Griffin, Xin Heng, Eli Hefner
  • Publication number: 20100328766
    Abstract: A system, apparatus and method for using modular microscopes is disclosed. Connecting the housings of the individual microscope modules provide the structural framework of the modular microscope. Furthermore, the modular microscope can include specialized software, the distribution and use of which can be controlled using security keys or identifiers stored on one or more of the microscope modules. The security keys and identifiers can be based on calibration data associated with the physical, electrical, or optical properties of one of more of the modules. The illumination modules disclosed provide for selectable wavelengths and controllable levels of output illumination for both bright field and dark field illumination.
    Type: Application
    Filed: June 28, 2010
    Publication date: December 30, 2010
    Applicant: Bio-Rad Laboratories, Inc.
    Inventors: Michael Griffin, Daniel Yue Man Chu, Tom McCollum
  • Patent number: 5298756
    Abstract: A flat response position sensitive neutron detector capable of providing neutron spectroscopic data utilizing scintillator fiber optic filaments embedded in a neutron moderating housing having an open end through which neutrons enter to be detected.
    Type: Grant
    Filed: October 16, 1992
    Date of Patent: March 29, 1994
    Assignee: Fibertek, Inc.
    Inventors: Tom McCollum, Garry B. Spector
  • Patent number: 4931646
    Abstract: A multichannel coincidence nuclear detector system for spectral charactertion of nuclear radiation sources at a remote location. The system is designed to detect and classify the radiation source in unfriendly territory and to provide a radio link back to a friendly receiver user station. The sensing elements are comprised of a plurality of plastic scintillator fiber sensors which may be several meters long and with each fiber having a different spectral sensitivity to gamma and neutron sources. Each of the scintillator fibers is connected to a transmitting optical fiber which may be 1 kilometer or more in length. The plurality of optical fibers transmit the optical signal generated by the radiation from a nuclear source impinging on the scintillator fibers to an electronic system. The electronic system is a sealed self contained battery operated device which is comprised of a photomuliplier detector and microprocessor based signal processing and data storage.
    Type: Grant
    Filed: March 17, 1989
    Date of Patent: June 5, 1990
    Assignee: The United States of America as Represented by the Secretary of the Army
    Inventors: Walter Koechner, Deborah R. Van Wyck, Garry B. Spector, Tom McCollum
  • Patent number: H801
    Abstract: A nuclear radiation detection system for remote monitoring of movement of nuclear material over a road or highway. Nuclear fiber sensors, which may be several meters long, are covertly positioned in at least two monitoring points, such as buried shallowly under the roadway or hung from a tunnel wall, along the path which a nuclear source may be clandestinely moved. These fiber sensors are individually connected, by an epoxy glue, to individual transmitting optical fibers. Movement of a nuclear radiation source in close proximity to the fiber sensors at the two or more monitoring points produces an optical signal which exceeds a preestablished threshold. These optical signals travel through the transmitting optical fibers, which may be about 1 kilometers long, to a electronic system comprised of a microprocessor controlled signal detecting, signal processing and even data storage means. The optical fibers and electronic system are also selectively hidden from view for security reasons.
    Type: Grant
    Filed: March 17, 1989
    Date of Patent: July 3, 1990
    Inventors: Walter Koechner, Deborah R. Van Wyck, Gary P. Stevenson, William Krug, Tom McCollum, Garry B. Spector