Patents by Inventor Tom McInally

Tom McInally has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMPOUNDS USEFUL IN MODULATION OF AHR SIGNALLING
    Publication number: 20250129092
    Abstract: Compounds of the general formula (I) as described and defined herein, methods for preparing said compounds, pharmaceutical compositions and combinations comprising said compounds and the use of said compounds and pharmaceutical compositions for the treatment or prevention of diseases, in particular cancer or conditions with dysregulated immune functions, or other conditions associated with aberrant AhR signalling, as a sole agent or in combination with other active ingredients.
    Type: Application
    Filed: August 31, 2022
    Publication date: April 24, 2025
    Inventors: Michael STOCKS, Mark GRAHAM, James HITCHIN, Tom MCINALLY, Vincenzo CILIBRASI, Sandy COMPAIN, Davide SBRAVATI
  • 8-oxoadenine derivatives acting as modulators of TLR7
    Patent number: 8138172
    Abstract: The present invention provides 8-oxoadenine derivatives, processes for their preparation, pharmaceutical compositions containing them and their use in therapy. The 8-oxoadenine derivatives act as modulators of Toll-like Receptor (TLR) 7 and thus may be used in the treatment of asthma, hepatitis, allergic diseases, viral and bacterial infection as well as cancer.
    Type: Grant
    Filed: July 3, 2007
    Date of Patent: March 20, 2012
    Assignees: AstraZeneca AB, Dainippon Sumitomo Pharma Co Ltd.
    Inventors: Anthony Cook, Tom McInally, Stephen Thom, Hiroki Wada
  • 8-OXOADENINE DERIVATIVES ACTING AS MODULATORS OF TLR7
    Publication number: 20100240623
    Abstract: The present invention provides 8-oxoadenine derivatives, processes for their preparation, pharmaceutical compositions containing them and their use in therapy. The 8-oxoadenine derivatives act as modulators of Toll-like Receptor (TLR) 7 and thus may be used in the treatment of asthma, hepatitis, allergic diseases, viral and bacterial infection as well as cancer.
    Type: Application
    Filed: July 3, 2007
    Publication date: September 23, 2010
    Inventors: Anthony Cook, Tom McInally, Stephen Thom, Hiroki Wada