Abstract: An assembly is provided which includes a package and a printed circuit board. The package includes a housing bounding a region and an acoustic sensor within the region. The housing includes a base with a first hole. The sensor is configured to generate signals indicative of sound received by the sensor through the first hole. The printed circuit board is in mechanical communication with the base and includes a second hole aligned with the first hole such that sound received by the second hole propagates through the first hole to the sensor. The printed circuit board further includes an electrically conductive layer, at least a portion of which extends across the second hole and is configured to allow the sound to propagate through the second hole and to at least partially shield the region containing the sensor from electromagnetic interference.

Abstract: A modular implant device configured for stimulation of at least one nerve or muscle in a body of a subject comprises: a housing; and at least one electrical lead, and/or at least one stimulation electrode; wherein the at least one electrical lead is partly disposed on the housing, and wherein the housing comprises modular elements, the modular elements being arranged in a stack. A system for electrical nerve stimulation comprises a network of at least two modular devices configured for implantation inside a body of a subject according to one of the preceding claims, wherein each modular device is electrically connected to at least one other modular device through electrical leads.

Abstract: An apparatus, including an implantable portion of a hearing prosthesis, wherein the apparatus is configured to at least partially cancel a signal in the implantable portion, the signal resulting from an external magnetic field generated external to a recipient of the hearing prosthesis. In an exemplary embodiment, the signal is a signal generated by the external magnetic field interacting with an electrical lead extending between a stimulation output device of the prosthesis and a stimulator and/or receiver of the implantable portion.

Abstract: An assembly is provided which includes a package and a printed circuit board. The package includes a housing bounding a region and an acoustic sensor within the region. The housing includes a base with a first hole. The sensor is configured to generate signals indicative of sound received by the sensor through the first hole. The printed circuit board is in mechanical communication with the base and includes a second hole aligned with the first hole such that sound received by the second hole propagates through the first hole to the sensor. The printed circuit board further includes an electrically conductive layer, at least a portion of which extends across the second hole and is configured to allow the sound to propagate through the second hole and to at least partially shield the region containing the sensor from electromagnetic interference.

Abstract: The present invention provides assays for the study of the interaction of EPF and its EPF-related peptides with a hDRR receptor. The assays are useful to identify whether a test compound can bind to the hDRR receptor under conditions in which EPF or related peptide can bind to the receptor. The assays are also useful to determine whether the test compound is an agonist or antagonist of hDRRs. The above assays can be performed in a variety of formats including competitive, non-competitive and comparative assays in which the interaction of EPF or EPF-related peptides with hDRRs is assessed as a positive or negative control or compared to the results obtained with the test compound.