Abstract: Isolated monoclonal agonistic antibodies which bind to human CD40 and related antibody-based compositions and molecules are disclosed. Also disclosed are therapeutic and diagnostic methods for using the antibodies.

Abstract: A centering assembly for an eddy current probe having a shaft includes a body portion configured to couple to the shaft and a plurality of wheels rotatably coupled to the body portion. At least a portion of each of the plurality of wheels projects beyond an outer surface of the body portion to engage a conduit under test.

Abstract: A method for automatic speech recognition using joint acoustic echo cancellation, speech enhancement, and voice separation includes receiving, at a contextual frontend processing model, input speech features corresponding to a target utterance. The method also includes receiving, at the contextual frontend processing model, at least one of a reference audio signal, a contextual noise signal including noise prior to the target utterance, or a speaker embedding including voice characteristics of a target speaker that spoke the target utterance. The method further includes processing, using the contextual frontend processing model, the input speech features and the at least one of the reference audio signal, the contextual noise signal, or the speaker embedding vector to generate enhanced speech features.

Abstract: A vaping system includes: (a) a disposable vaping device that includes the following non user-replaceable items: (i) a heating element; (ii) a rechargeable battery, and (iii) a liquid reservoir that provides liquid to the heating element; and (b) an automatic liquid filling device, including (i) a first aperture or port configured to receive a liquid bottle or container containing atomisable liquid; (ii) a second aperture or port configured to receive the vaping device; (iii) an electronic liquid level sensing sub-system; (iv) a liquid filling sub-system configured to pump liquid from the liquid bottle or container to the liquid reservoir in the vaping device and (v) a battery charging sub-system.

Abstract: A vaping system includes: (a) a disposable vaping device that includes the following non user-replaceable items: (i) a heating element; (ii) a rechargeable battery, and (iii) a liquid reservoir that provides liquid to the heating element; and (b) an automatic liquid filling device, including (i) a first aperture or port configured to receive a liquid bottle or container containing atomisable liquid; (ii) a second aperture or port configured to receive the vaping device; (iii) an electronic liquid level sensing sub-system; (iv) a liquid filling sub-system configured to pump liquid from the liquid bottle or container to the liquid reservoir in the vaping device and (v) a battery charging sub-system.

Abstract: A method for automatic speech recognition using joint acoustic echo cancellation, speech enhancement, and voice separation includes receiving, at a contextual frontend processing model, input speech features corresponding to a target utterance. The method also includes receiving, at the contextual frontend processing model, at least one of a reference audio signal, a contextual noise signal including noise prior to the target utterance, or a speaker embedding including voice characteristics of a target speaker that spoke the target utterance. The method further includes processing, using the contextual frontend processing model, the input speech features and the at least one of the reference audio signal, the contextual noise signal, or the speaker embedding vector to generate enhanced speech features.

Abstract: Disclosed herein are bi-spring surgical impact tools and methods of use thereof. The bi-spring surgical impact tools can include a housing, a shuttle, a pinion, and first and second springs. The housing can define a cavity having a first end and a second end. The shuttle can be located within the cavity and define a plurality of indentations. The pinion can be located proximate the shuttle and have a plurality of protrusions sized to mesh with the plurality of indentations during rotation of the pinion. The first and second springs can be mechanically coupled to the housing and the shuttle. Rotation of the pinion in a first direction can translate the shuttle in a first direction towards the first end of the housing and rotation of the pinion in a second direction can translate the shuttle in a second direction towards the second end of the housing.

Abstract: A method of producing a component for an article of footwear or apparel or a sporting goods accessory. The method of producing a component includes forming at least a first layer by braiding a first braided tube. Braiding may be performed with an empty braiding center. The method further includes arranging the first layer on a form.

Abstract: Disclosed is a surgical fixation device to mount on bone. This device does not utilize screws and achieves stability via applying force to the inner wall of the bore and is therefore faster, easier to use, and less user dependent. The device facilitates fast, easy anchoring system for use with other devices that require rigid fixation to bone. The device provides for intermittent mounting of tools, equipment, and/or accessories to a cylindrical bore in bone for use in surgical applications without compromising surrounding bine structure such as done by the use of bone screws. Rigid fixation to bone is a common requirement for surgical procedures for placement of tools, monitoring systems, positional systems, or used as fiducial markers. The present fixation device removably mounts on bone without the disadvantages associated with bone screws and other fixation devices.

Abstract: Described is a circularly-woven tube for an article of footwear or an article of apparel comprising: a plurality of warp yarns, having a first elastic modulus; a plurality of weft yarns, having a second elastic modulus, and wherein the second elastic modulus is smaller than the first elastic modulus.

Abstract: The present invention concerns a shoe upper comprising a woven portion, wherein the woven portion comprises a plurality of warp yarns; a plurality of weft yarns; at least one stitching yarn, wherein the stitching yarn is integrally woven into the fabric during the weaving process by laterally displacing the stitching yarn substantially along the weft direction and moving the stitching yarn in and out of at least one open reed gap in a reed.

Abstract: Described is a circularly-woven tube for an article of footwear or an article of apparel comprising: a plurality of warp yarns, having a first elastic modulus; a plurality of weft yarns, having a second elastic modulus, and wherein the second elastic modulus is smaller than the first elastic modulus.

Abstract: A multichannel neural frontend speech enhancement model for speech recognition includes a speech cleaner, a stack of self-attention blocks each having a multi-headed self attention mechanism, and a masking layer. The speech cleaner receives, as input, a multichannel noisy input signal and a multichannel contextual noise signal, and generates, as output, a single channel cleaned input signal. The stack of self-attention blocks receives, as input, at an initial block of the stack of self-attention blocks, a stacked input including the single channel cleaned input signal and a single channel noisy input signal, and generates, as output, from a final block of the stack of self-attention blocks, an un-masked output. The masking layer receives, as input, the single channel noisy input signal and the un-masked output, and generates, as output, enhanced input speech features corresponding to a target utterance.

Abstract: A method for training a generalized automatic speech recognition model for joint acoustic echo cancellation, speech enhancement, and voice separation includes receiving a plurality of training utterances paired with corresponding training contextual signals. The training contextual signals include a training contextual noise signal including noise prior to the corresponding training utterance, a training reference audio signal, and a training speaker vector including voice characteristics of a target speaker that spoke the corresponding training utterance. The operations also include training, using a contextual signal dropout strategy, a contextual frontend processing model on the training utterances to learn how to predict enhanced speech features. Here, the contextual signal dropout strategy uses a predetermined probability to drop out each of the training contextual signals during training of the contextual frontend processing model.

Abstract: A computer-implemented method includes receiving a sequence of acoustic frames corresponding to an utterance and generating a reference speaker embedding for the utterance. The method also includes receiving a target speaker embedding for a target speaker and generating feature-wise linear modulation (FiLM) parameters including a scaling vector and a shifting vector based on the target speaker embedding. The method also includes generating an affine transformation output that scales and shifts the reference speaker embedding based on the FiLM parameters. The method also includes generating a classification output indicating whether the utterance was spoken by the target speaker based on the affine transformation output.

Abstract: Systems, apparatuses, and method of measuring hydrophone impedance are provided herein. A sensor can convert an acoustic wave received via a liquid medium into an electric signal. A signal encoder can be coupled with the sensor to receive the electric signal. A test signal generator can be coupled in series with the sensor and the signal encoder and can generate a test signal. The test signal can measure an impedance of the sensor. A switch component can be coupled in series with the sensor, the signal encoder, and the test signal generator. The switch component can route the test signal to a first terminal of the sensor and through a second terminal of sensor during a first operational state. The switch component can route the test signal to the second terminal of the sensor and through the first terminal of sensor during a second operational state.

Abstract: A method of producing a component for an article of footwear or apparel or a sporting goods accessory. The method of producing a component includes forming at least a first layer by braiding a first braided tube. Braiding may be performed with an empty braiding center. The method further includes arranging the first layer on a form.

Abstract: A method for automatic speech recognition using joint acoustic echo cancellation, speech enhancement, and voice separation includes receiving, at a contextual frontend processing model, input speech features corresponding to a target utterance. The method also includes receiving, at the contextual frontend processing model, at least one of a reference audio signal, a contextual noise signal including noise prior to the target utterance, or a speaker embedding including voice characteristics of a target speaker that spoke the target utterance. The method further includes processing, using the contextual frontend processing model, the input speech features and the at least one of the reference audio signal, the contextual noise signal, or the speaker embedding vector to generate enhanced speech features.

Abstract: Methods for producing at least a part of a sporting good, in particular a sports shoe, can include: (a) depositing a first material into a mold, and (b) vibrating the mold to modify the distribution of the first material in the mold.

Abstract: A flexible eddy current probe for non-destructive testing of a metallic object may include one or more plus-point coils and a flexible printed circuit having first and second parallel sides, third and fourth parallel sides, and a number of adjacent strips. The strips have first and second ends that are contiguous with the first and second parallel sides, respectively. Each of the strips may contain a pair of coils oriented along the length of the strip, a first coil being proximate to the first end and a second coil being proximate to the second end, and each of the coils is configured to excite an eddy current in the metal object or to sense an eddy current. Each of the strips may also be independently flexible from one another. The eddy current sensor array is configured to be scanned over the metal object.