Patents by Inventor Tomás Werner

Tomás Werner has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20190390214
    Abstract: The present invention provides a method for improving traits in a plant, like e.g. improving yield-related traits like number of flowers, number of siliques, seed yield, stem growth in a plant, the method comprising disruption of endogenous ROCK1 gene in a plant cell, wherein said disruption inhibits expression and/or activity of a product of said endogenous ROCK1 gene compared to a corresponding control plant cell lacking such a disruption.
    Type: Application
    Filed: August 28, 2019
    Publication date: December 26, 2019
    Inventors: Thomas SCHMUELLING, Michael NIEMANN, Tomàs WERNER
  • Patent number: 9422570
    Abstract: The present invention is directed to a method for increasing seed yield in a plant, the method comprising disruption of endogenous AHP6 gene in cells of the plant, wherein said disruption inhibits expression and/or activity of a product of said endogenous AHP6 gene compared to a corresponding control plant lacking such a disruption.
    Type: Grant
    Filed: December 16, 2011
    Date of Patent: August 23, 2016
    Inventors: Thomas Schmülling, Tomas Werner
  • Patent number: 9127073
    Abstract: The present invention relates to two new gain of function variants of the cytokinin receptor proteins AHK2 and AHK3, namely rock2 and rock3, to transgenic organisms comprising at least one of said new gain-of-function cytokinin receptor variants and to a method for the manufacturing of a transgenic plant comprising at least one of the new gain-of-function variants.
    Type: Grant
    Filed: July 9, 2010
    Date of Patent: September 8, 2015
    Assignee: Freie Universitat Berlin
    Inventors: Thomas Schmülling, Tomás Werner, Isabel Bartrina y Manns, Helen Braun
  • Publication number: 20140380526
    Abstract: The present invention is directed to isolated plant cells and transgenic plants comprising a disruption in at least a CKX3 gene and in one further gene encoding for a cytokininoxidase/dehydrogenase and being different from CKX3 well as to methods of producing such transgenic plants and to methods of increasing seed yield in a plant and/or plant height.
    Type: Application
    Filed: August 4, 2014
    Publication date: December 25, 2014
    Inventors: Thomas SCHMÜLLING, Isabel BARTRINA Y MANNS, Tomás WERNER
  • Patent number: 8859854
    Abstract: The present invention provides methods and compositions for increasing seed size and/or weight, embryo size and/or weight, and cotyledon size and/or weight. The methods comprise expression of a cytokinin oxidase or expression of another protein that reduces the level of active cytokinins in plants or plant parts. Methods and compositions for increasing seed yield are also provided. The invention also relates to isolated plant cytokinin oxidase proteins, nucleic acid sequences encoding cytokinin oxidase proteins as well as to vectors, host cells, transgenic cells and plants comprising such sequences.
    Type: Grant
    Filed: July 2, 2012
    Date of Patent: October 14, 2014
    Inventors: Thomas Schmulling, Tomas Werner
  • Patent number: 8766038
    Abstract: The present invention relates to methods for stimulating root growth and/or enhancing the formation of lateral or adventitious roots and/or altering root geotropism comprising expression of a plant cytokinin oxidase or comprising expression of another protein that reduces the level of active cytokinins in plants or plant parts. The invention also relates to novel plant cytokinin oxidase proteins, nucleic acid sequences encoding cytokinin oxidase proteins as well as to vectors, host cells, transgenic cells and plants comprising said sequences. The invention also relates to the use of said sequences for improving root-related characteristics including increasing yield and/or enhancing early vigor and/or modifying root/shoot ratio and/or improving resistance to lodging and/or increasing drought tolerance and/or promoting in vitro propagation of explants and/or modifying cell fate and/or plant development and/or plant morphology and/or plant biochemistry and/or plant physiology.
    Type: Grant
    Filed: May 16, 2007
    Date of Patent: July 1, 2014
    Inventors: Thomas Schmulling, Tomas Werner
  • Patent number: 8722967
    Abstract: The present invention relates to methods for increasing seed size and/or weight, embryo size and/or weight, and cotyledon size and/or weight. The methods comprise expression of a cytokinin oxidase in plants or plant parts, preferably in seeds, embryos and/or cotyledons. The methods result in increases in: yield, growth of seedlings, early vigor, and stress tolerance. The invention also relates to isolated plant cytokinin oxidase proteins, nucleic acid sequences encoding cytokinin oxidase proteins as well as to vectors, host cells, transgenic cells and plants comprising such sequences.
    Type: Grant
    Filed: May 11, 2012
    Date of Patent: May 13, 2014
    Inventors: Thomas Schmulling, Tomas Werner
  • Publication number: 20130269062
    Abstract: The present invention is directed to a method for increasing seed yield in a plant, the method comprising disruption of endogenous AHP6 gene in cells of the plant, wherein said disruption inhibits expression and/or activity of a product of said endo genus AHP6 gene compared to a corresponding control plant lacking such a disruption.
    Type: Application
    Filed: December 16, 2011
    Publication date: October 10, 2013
    Inventors: Thomas Schmülling, Tomas Werner
  • Publication number: 20130007922
    Abstract: The present invention provides methods and compositions for increasing seed size and/or weight, embryo size and/or weight, and cotyledon size and/or weight. The methods comprise expression of a cytokinin oxidase or expression of another protein that reduces the level of active cytokinins in plants or plant parts. Methods and compositions for increasing seed yield are also provided. The invention also relates to isolated plant cytokinin oxidase proteins, nucleic acid sequences encoding cytokinin oxidase proteins as well as to vectors, host cells, transgenic cells and plants comprising such sequences.
    Type: Application
    Filed: July 2, 2012
    Publication date: January 3, 2013
    Inventors: Thomas Schmulling, Tomàs Werner
  • Publication number: 20120311742
    Abstract: The present invention relates to methods for increasing seed size and/or weight, embryo size and/or weight, and cotyledon size and/or weight. The methods comprise expression of a cytokinin oxidase in plants or plant parts, preferably in seeds, embryos and/or cotyledons. The methods result in increases in: yield, growth of seedlings, early vigor, and stress tolerance. The invention also relates to isolated plant cytokinin oxidase proteins, nucleic acid sequences encoding cytokinin oxidase proteins as well as to vectors, host cells, transgenic cells and plants comprising such sequences.
    Type: Application
    Filed: May 11, 2012
    Publication date: December 6, 2012
    Inventors: Thomas Schmulling, Tomàs Werner
  • Publication number: 20120272409
    Abstract: The present invention relates to two new gain of function variants of the cytokinin receptor proteins AHK2 and AHK3, namely rock2 and rock3, to transgenic organisms comprising at least one of said new gain-of-function cytokinin receptor variants and to a method for the manufacturing of a transgenic plant comprising at least one of the new gain-of-function variants.
    Type: Application
    Filed: July 9, 2010
    Publication date: October 25, 2012
    Inventors: Thomas Schmülling, Tomás Werner, Isabel Bartrina Y Manns, Helen Braun
  • Patent number: 8227663
    Abstract: The present invention relates to methods for stimulating root growth and/or enhancing the formation of lateral or adventitious roots and/or altering root geotropism comprising expression of a cytokinin oxidase or comprising expression of another protein that reduces the level of active cytokinins in plants or plant parts. Also provided by the present invention are methods for increasing seed size and/or weight, embryo size and/or weight, and cotyledon size and/or weight. The methods comprise expression of a cytokinin oxidase or expression of another protein that reduces the level of active cytokinins in plants or plant parts. Methods and compositions for increasing seed yield are also provided. The invention also relates to isolated plant cytokinin oxidase proteins, nucleic acid sequences encoding cytokinin oxidase proteins as well as to vectors, host cells, transgenic cells and plants comprising such sequences.
    Type: Grant
    Filed: November 7, 2008
    Date of Patent: July 24, 2012
    Inventors: Thomas Schmülling, Tomàs Werner
  • Patent number: 8222260
    Abstract: The invention relates to substituted 6-anilinopurine derivatives of the general formula I, wherein R denotes one to five substituents independently selected from the group consisting of hydrogen, halogen, hydroxyl, amino, alkyloxy and alkyl group, and R2 denotes amino, halogen, nitro, thio, alkylthio or alkyl group for use as inhibitors of cytokinin oxidase/dehydrogenase. The invention also relates to the compositions containing these derivatives.
    Type: Grant
    Filed: July 2, 2008
    Date of Patent: July 17, 2012
    Assignees: Univerzita Palackego V Olomouci, Freie Universitat Berlin
    Inventors: Lukas Spichal, Marketa Gemrotova, Marek Zatloukal, Jitka Frebortova, Petr Galuszka, Tomas Werner, Thomas Schmulling, Karel Dolezal, Miroslav Strnad
  • Publication number: 20120167254
    Abstract: The present invention is directed to isolated plant cells and transgenic plants comprising a disruption in at least a CKX3 gene and in one further gene encoding for a cytokininoxidase/dehydrogenase and being different from CKX3 well as to methods of producing such transgenic plants and to methods of increasing seed yield in a plant and/or plant height.
    Type: Application
    Filed: July 9, 2010
    Publication date: June 28, 2012
    Inventors: Thomas Schmülling, Isabel Bartrina Y Manns, Tomás Werner
  • Patent number: 8138389
    Abstract: The present invention provides nucleotide sequences and corresponding amino acid sequences for plant cytokinin oxidase proteins. In addition, vectors, host cells, and transgenic plants comprising such sequences as well as methods for stimulating root growth and/or enhancing the formation of lateral or adventitious roots and/or altering root geotropism using such sequences are provided by the present invention. Also provided by the present invention are methods for altering various plant phenotypes including delaying onset to flowering, increasing leaf thickness, reducing vessel size, inducing parthenocarpy, increasing branching, increasing seed size and/or weight, embryo size and/or weight, and cotyledon size and/or weight using cytokinin oxidase proteins and/or nucleic acid molecules encoding cytokinin oxidase.
    Type: Grant
    Filed: July 27, 2010
    Date of Patent: March 20, 2012
    Inventors: Thomas Schmulling, Tomas Werner
  • Publication number: 20110023186
    Abstract: The present invention provides nucleotide sequences and corresponding amino acid sequences for plant cytokinin oxidase proteins. In addition, vectors, host cells, and transgenic plants comprising such sequences as well as methods for stimulating root growth and/or enhancing the formation of lateral or adventitious roots and/or altering root geotropism using such sequences are provided by the present invention. Also provided by the present invention are methods for altering various plant phenotypes including delaying onset to flowering, increasing leaf thickness, reducing vessel size, inducing parthenocarpy, increasing branching, increasing seed size and/or weight, embryo size and/or weight, and cotyledon size and/or weight using cytokinin oxidase proteins and/or nucleic acid molecules encoding cytokinin oxidase.
    Type: Application
    Filed: July 27, 2010
    Publication date: January 27, 2011
    Inventors: Thomas Schmülling, Tomás Werner
  • Patent number: 7807879
    Abstract: The present invention provides nucleotide sequences and corresponding amino acid sequences for plant cytokinin oxidase proteins. In addition, vectors, host cells, and transgenic plants comprising such sequences as well as methods for stimulating root growth and/or enhancing the formation of lateral or adventitious roots and/or altering root geotropism using such sequences are provided by the present invention. Also provided by the present invention are methods for altering various plant phenotypes including delaying onset to flowering, increasing leaf thickness, reducing vessel size, inducing parthenocarpy, increasing branching, increasing seed size and/or weight, embryo size and/or weight, and cotyledon size and/or weight using cytokinin oxidase proteins and/or nucleic acid molecules encoding cytokinin oxidase.
    Type: Grant
    Filed: May 8, 2007
    Date of Patent: October 5, 2010
    Inventors: Thomas Schmülling, Tomás Werner
  • Publication number: 20100240537
    Abstract: The invention relates to 6-(alkylbenzylamino)purine derivatives of the general formula I for use as cytokinin receptor antagonists, wherein R1 is selected from the group comprising hydroxyl, amino, nitro, thio and alkyl group, and R2 denotes one to four alkyl groups. The invention also relates to preparations containing these derivatives.
    Type: Application
    Filed: October 3, 2008
    Publication date: September 23, 2010
    Inventors: Lukas Spichal, Igor Popa, Jiri Voller, Karel Dolezal, Miroslav Strnad, Tomas Werner, Thomas Schmulling
  • Publication number: 20100190806
    Abstract: The invention relates to substituted 6-anilinopurine derivatives of the general formula I, wherein R denotes one to five substituents independently selected from the group consisting of hydrogen, halogen, hydroxyl, amino, alkyloxy and alkyl group, and R2 denotes amino, halogen, nitro, thio, alkylthio or alkyl group for use as inhibitors of cytokinin oxidase/dehydrogenase. The invention also relates to the compositions containing these derivatives.
    Type: Application
    Filed: July 2, 2008
    Publication date: July 29, 2010
    Inventors: Lukas Spichal, Marketa Gemrotova, Marek Zatloukal, Jitka Frebortova, Petr Galuszka, Tomas Werner, Thomas Schmulling, Karel Dolezal, Miroslav Strnad
  • Patent number: 7619146
    Abstract: The present invention relates to methods for stimulating root growth and/or enhancing the formation of lateral or adventitious roots and/or altering root geotropism comprising expression of a cytokinin oxidase or comprising expression of another protein that reduces the level of active cytokinins in plants or plant parts. Also provided by the present invention are methods for increasing seed size and/or weight, embryo size and/or weight, and cotyledon size and/or weight. The methods comprise expression of a cytokinin oxidase or expression of another protein that reduces the level of active cytokinins in plants or plant parts. Methods and compositions for increasing seed yield are also provided. The invention also relates to isolated plant cytokinin oxidase proteins, nucleic acid sequences encoding cytokinin oxidase proteins as well as to vectors, host cells, transgenic cells and plants comprising such sequences.
    Type: Grant
    Filed: February 14, 2005
    Date of Patent: November 17, 2009
    Inventors: Valérie Frankard, Thomas Schmülling, Tomàs Werner