Abstract: A head-mounted display (HMD) determines whether a set of criteria is satisfied based on eye-related readings collected by a camera of the HMD and wirelessly transmits a set of messages in response to a determination that the set of criteria is satisfied. An attachment includes a set of light-emitting diodes (LEDs) and activates the set of LEDs to emit the light at the bleaching intensity in response to receiving the set of messages.

Abstract: Provided herein are compounds of formula (I): and pharmaceutically-acceptable salts thereof, where A, W, X, Y and Z are defined in the specification. The compounds of formula (I) and pharmaceutically-acceptable salts thereof are Janus kinase (JAK) inhibitors. Also provided herein are pharmaceutical compositions comprising such compounds; and methods of using such compounds to treat, e.g., inflammatory and fibrotic diseases, including respiratory diseases.

Abstract: The present invention relates to polypeptides which are covalently bound to molecular scaffolds such that two or more peptide loops are subtended between attachment points to the scaffold. In particular, the invention describes peptides which bind to TREM2. The invention also relates to multimeric binding complexes which comprise at least two of said bicyclic peptide ligands. The invention also includes pharmaceutical compositions comprising said peptide ligands and multimeric binding complexes and the use of said peptide ligands, multimeric binding complexes and pharmaceutical compositions in preventing, suppressing or treating a disease or disorder mediated by TREM2.

Abstract: A system is provided for producing composite products including a substrate and a resin integrated with the substrate.

Abstract: The present invention relates to polypeptides which are covalently bound to molecular scaffolds such that two or more peptide loops are subtended between attachment points to the scaffold. In particular, the invention describes peptides which bind to TREM2. The invention also relates to multimeric binding complexes which comprise at least two of said bicyclic peptide ligands. The invention also includes pharmaceutical compositions comprising said peptide ligands and multimeric binding complexes and the use of said peptide ligands, multimeric binding complexes and pharmaceutical compositions in preventing, suppressing or treating a disease or disorder mediated by TREM2.

Abstract: A double-sided root barrier has an inside channel formed on an inside surface. The inside channel is formed between the inside channel inside surface and the transition area inside surface. The transition area inside surface is formed at an angle to an outside channel inside surface. The outside channel inside surface is formed at an angle to the inside surface. An outside channel is formed on an outside surface, and the outside channel is formed between an outside channel outside surface and a transition area outside surface. The transition area outside surface is parallel to the transition area inside surface. The outside channel outside surface is parallel to the outside channel inside surface, and the transition area outside surface is formed at an angle to the inside channel outside surface.

Abstract: A system includes a first trolley and a second trolley movably suspended from a support track. The first trolley includes a patient attachment mechanism configured to support a first patient. The first trolley is configured to move relative to the support track. The second trolley includes a patient attachment mechanism configured to support a second patient. The second trolley is configured to move relative to the support track such that the movement of the second trolley is independent of the movement of the first trolley. A collision management assembly is configured to be coupled to one of the first trolley and the second trolley. The collision management assembly includes a bumper that is configured to prevent the first trolley from directly contacting the second trolley.

Abstract: A video signal caption system is described, which includes a receiver for receiving video signals, and a computer configured to process, at least, caption data included with the video signals, including storing a plurality of caption information corresponding to portions of the caption data in a database, detecting when received video signals contain one or more portions of caption data which correspond to caption information stored in the database, and communicating that a detection has been made.

Abstract: A method of influencing access to website, social media or mobile application content is described. The method comprises identifying the occurrence of an item of live or previously broadcast media content, identifying consumer Internet activity at the time of the occurrence of the item of media content, and identifying, from said detected consumer internet activity, a strategy to influence an Internet search function, social media site or mobile application to display selected information. Then, a subsequent broadcast of the item of media content is identified, and the identified strategy is triggered at the point the item occurs during the time of the identified subsequent broadcast.

Abstract: An orthotic system includes a controller, a joint and a fail-safe system for the joint. In a preferred embodiment, the orthotic system is an exoskeleton, the joint is a knee joint and the fail-safe system is a normally engaged brake that is controlled by the controller. The brake is engaged when the controller fails or the exoskeleton is powered off. The exoskeleton also includes an electrical or mechanical brake disengagement mechanism, separate from the controller, so that an exoskeleton user can disengage the brake when desired. The exoskeleton can also include an override mechanism that prevents the brake disengagement mechanism from functioning when the exoskeleton is powered on and the controller has not failed. Additionally, the exoskeleton can include a user interface at one location, with the brake disengagement mechanism located at a different, limited access location, so that the user cannot accidentally activate the brake disengagement mechanism.

Abstract: A comprehensive and holistic behavior-based customer characterization scheme is presented. Specifically, the characterization scheme includes internal credit behavior segmentation and external credit segmentation. In other embodiments, the characterization includes internal credit behavior segmentation and external credit segmentation, and spend preference segmentation. In still further embodiments any combination of behavior algorithms may be implemented to characterize the customer base and determine a related customer profile. The application additionally provides for new behavior algorithms to be added as needed in the future and the ability to interface with existing/legacy segmentation applications.

Abstract: A disc holder dock includes a top cover having an opening for a driving wheel. The top cover has a cradle area for docking a gyroscopic wrist exerciser. The top cover further has a guide vane for directional guiding of the gyroscopic wrist exerciser. The top cover has a top cover sidewall. A middle frame mounted to the top cover. The driving wheel is mounted to the middle frame. The driving wheel is connected to the middle frame by a support. A lower plate is for holding a disc. The lower plate has a lower plate upper side and a lower plate lower side. The lower plate further includes a disk storage area.

Abstract: A system includes a first trolley and a second trolley movably suspended from a support track. The first trolley includes a patient attachment mechanism configured to support a first patient. The first trolley is configured to move relative to the support track. The second trolley includes a patient attachment mechanism configured to support a second patient. The second trolley is configured to move relative to the support track such that the movement of the second trolley is independent of the movement of the first trolley. A collision management assembly is configured to be coupled to one of the first trolley and the second trolley. The collision management assembly includes a bumper that is configured to prevent the first trolley from directly contacting the second trolley.

Abstract: An orthotic system includes a controller, a joint and a fail-safe system for the joint. In a preferred embodiment, the orthotic system is an exoskeleton, the joint is a knee joint and the fail-safe system is a normally engaged brake that is controlled by the controller. The brake is engaged when the controller fails or the exoskeleton is powered off. The exoskeleton also includes an electrical or mechanical brake disengagement mechanism, separate from the controller, so that an exoskeleton user can disengage the brake when desired. The exoskeleton can also include an override mechanism that prevents the brake disengagement mechanism from functioning when the exoskeleton is powered on and the controller has not failed. Additionally, the exoskeleton can include a user interface at one location, with the brake disengagement mechanism located at a different, limited access location, so that the user cannot accidentally activate the brake disengagement mechanism.

Abstract: A gyroscopic wrist exerciser has a transparent plastic housing and a gyroscopic rotor mounted on an axle rotating on a primary axis of rotation about the axle. Ends of the axle are extended into a circumferential housing groove disposed on an inside surface of the transparent plastic housing to rotate in a secondary axis of rotation about the circumferential groove to provide precession of the gyroscopic rotor. A permanent magnet cooperating with a coil produces an electric current proportional to the speed of the rotor. A microcontroller connected to and powered by the coil has three separate outputs, namely a first output, a second output and a third output which receive degrees of voltage depending upon an input voltage from the coil. A first LED chip, a second LED chip, and a third LED chip are connected to the microcontroller at the three outputs.

Abstract: A gyroscope power starter has a housing having a bottom and a concave head slanted at a predetermined angle relative to the housing, the concave head engaging a gyroscope rotor. An electric power source is mounted on the housing. A motor is rigidly mounted to a housing. The motor is connected to the power source for producing a rotational power in response to a switching force. A power rotor is connected in unity with the motor and protruding from an opening into the concave head of the housing to transmit the rotational motor power to the gyroscope rotor. An alignment member is formed in a concave center area. The alignment member protrudes into a groove of a gyroscopic rotor when the gyroscopic rotor is rotating.

Abstract: A gyroscopic exerciser starting dock has a starter dock housing and a starter dock axle mounted within the starter dock housing. A driving wheel is mounted to the starter dock axle. A retractable pull cord grip sleeve device is mounted to the starter dock axle and has a pull handle attached to a pull cord. The pull handle is for pulling the pull cord, and the pull cord is attached to the handle at a pull cord first end. A spool receives around it a pull cord and a pull cord is attached to the spool at a pull cord second end. The spool member receives and stores the pull cord in a coil around the spool.

Abstract: A new and distinct cultivar of Verbena plant named ‘RIKA18302M’, characterized by its compact, outwardly spreading and mounding to eventually trailing plant habit; vigorous growth habit; freely branching habit; dark green-colored leaves; freely flowering habit; light violet blue and white bi-colored flowers that are held at or above and beyond the foliar plane; and relative resistance to Powdery Mildew (Podosphaera xanthii).