Patents by Inventor Tom Tao Huang

Tom Tao Huang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS FOR TRANSDUCING IMMUNE CELLS
    Publication number: 20220249556
    Abstract: Provided herein are improved methods for transducing immune cells, such as T cells, with retroviral vectors to express exogenous gene products, such as chimeric antigen receptors (CARs). Provided herein are methods that increase transduction efficiency thereby increasing the percentage of immune cells in a population expressing the exogenous gene product. Associated cells, cell populations, compositions and methods of use are also provided.
    Type: Application
    Filed: January 28, 2022
    Publication date: August 11, 2022
    Inventors: Todd LUMAN, Josergio ZARAGOZA, Abraham GERMANSDERFER, Suma RAO, Yajin NI, Chupei ZHANG, Tom Tao HUANG
  • CARBOHYDRATE ESTERS AS INDUCERS FOR GENE EXPRESSION
    Publication number: 20210079438
    Abstract: The invention provides novel carbohydrate esters, in particular disaccharide esters, and the methods of their preparation. These compounds find use as microbial media components for the induction of gene expression in microbial fermentation processes.
    Type: Application
    Filed: November 20, 2020
    Publication date: March 18, 2021
    Inventor: Tom Tao Huang
  • Method of using carbohydrate esters as inducers for gene expression
    Patent number: 10870873
    Abstract: The invention provides novel carbohydrate esters, in particular disaccharide esters, and the methods of their preparation. These compounds find use as microbial media components for the induction of gene expression in microbial fermentation processes.
    Type: Grant
    Filed: June 27, 2018
    Date of Patent: December 22, 2020
    Assignee: Qingdao Viand Biotech Group Co., Ltd.
    Inventor: Tom Tao Huang
  • CARBOHYDRATE ESTERS AS INDUCERS FOR GENE EXPRESSION
    Publication number: 20180327804
    Abstract: The invention provides novel carbohydrate esters, in particular disaccharide esters, and the methods of their preparation. These compounds find use as microbial media components for the induction of gene expression in microbial fermentation processes.
    Type: Application
    Filed: June 27, 2018
    Publication date: November 15, 2018
    Inventor: TOM TAO HUANG
  • Carbohydrate esters as inducers for gene expression
    Patent number: 10059973
    Abstract: The invention provides novel carbohydrate esters, in particular disaccharide esters, and the methods of their preparation. These compounds find use as microbial media components for the induction of gene expression in microbial fermentation processes.
    Type: Grant
    Filed: July 18, 2013
    Date of Patent: August 28, 2018
    Assignee: QINGDAO VLAND BIOTECH GROUP CO., LTD.
    Inventor: Tom Tao Huang
  • Chemically modified sophorolipids and uses thereof
    Patent number: 9828592
    Abstract: The present disclosure provides a sophorolipid composition that can be used for inducing protein expression in a fermentation host. The sophorolipid composition described herein can be prepared from a natural sophorolipid mixture. Acid treatment of the natural sophorolipid mixture results in a mixture of monoacetylated, deacetylated, and/or diacetylated sophorolipids. The chemically modified sophorolipid composition, or isolated components of the chemically modified sophorolipid composition, can be used as inducers for protein production in filamentous fungi.
    Type: Grant
    Filed: November 5, 2015
    Date of Patent: November 28, 2017
    Assignee: Qingdao Vland Biotech Group Co., Ltd.
    Inventor: Tom Tao Huang
  • CHEMICALLY MODIFIED SOPHOROLIPIDS AND USES THEREOF
    Publication number: 20160122736
    Abstract: The present disclosure provides a sophorolipid composition that can be used for inducing protein expression in a fermentation host. The sophorolipid composition described herein can be prepared from a natural sophorolipid mixture. Acid treatment of the natural sophorolipid mixture results in a mixture of monoacetylated, deacetylated, and/or diacetylated sophorolipids. The chemically modified sophorolipid composition, or isolated components of the chemically modified sophorolipid composition, can be used as inducers for protein production in filamentous fungi.
    Type: Application
    Filed: November 5, 2015
    Publication date: May 5, 2016
    Applicant: SOPHORO BIOTECHNOLOGIES, LLC
    Inventor: Tom Tao Huang
  • Chemically modified sophorolipids and uses thereof
    Patent number: 9206407
    Abstract: The present disclosure provides a sophorolipid composition that can be used for inducing protein expression in a fermentation host. The sophorolipid composition described herein can be prepared from a natural sophorolipid mixture. Acid treatment of the natural sophorolipid mixture results in a mixture of monoacetylated, deacetylated, and/or diacetylated sophorolipids. The chemically modified sophorolipid composition, or isolated components of the chemically modified sophorolipid composition, can be used as inducers for protein production in filamentous fungi.
    Type: Grant
    Filed: June 25, 2012
    Date of Patent: December 8, 2015
    Assignee: Sophoro Biotechnologies, LLC
    Inventor: Tom Tao Huang
  • Carbohydrate Esters as Inducers for Gene Expression
    Publication number: 20150152462
    Abstract: The invention provides novel carbohydrate esters, in particular disaccharide esters, and the methods of their preparation. These compounds find use as microbial media components for the induction of gene expression in microbial fermentation processes.
    Type: Application
    Filed: July 18, 2013
    Publication date: June 4, 2015
    Applicant: Sophoro Biotechnologies, LLC
    Inventor: Tom Tao Huang
  • CHEMICALLY MODIFIED SOPHOROLIPIDS AND USES THEREOF
    Publication number: 20140322755
    Abstract: The present disclosure provides a sophorolipid composition that can be used for inducing protein expression in a fermentation host. The sophorolipid composition described herein can be prepared from a natural sophorolipid mixture. Acid treatment of the natural sophorolipid mixture results in a mixture of monoacetylated, deacetylated, and/or diacetylated sophorolipids. The chemically modified sophorolipid composition, or isolated components of the chemically modified sophorolipid composition, can be used as inducers for protein production in filamentous fungi.
    Type: Application
    Filed: June 25, 2012
    Publication date: October 30, 2014
    Inventor: Tom Tao Huang
  • Fermentation broth formulations
    Patent number: 8679824
    Abstract: The present disclosure relates to fermentation broth formulations containing organic acids and/or organic acid salts, and methods of making and using such formulations.
    Type: Grant
    Filed: February 19, 2010
    Date of Patent: March 25, 2014
    Assignee: Danisco US Inc.
    Inventors: Tom Tao Huang, Aaron Kelley, John McLaughlin
  • FERMENTATION BROTH FORMULATIONS
    Publication number: 20120015422
    Abstract: The present disclosure relates to fermentation broth formulations containing organic acids and/or organic acid salts, and methods of making and using such formulations.
    Type: Application
    Filed: February 19, 2010
    Publication date: January 19, 2012
    Inventors: Tom Tao Huang, Aaron Kelley, John Mclaughlin
  • SWOLLENIN COMPOSITIONS AND METHODS OF INCREASING THE EFFICIENCY OF A CELLULASE
    Publication number: 20110136182
    Abstract: Described are compositions and methods relating to enhancing the efficiency of cellulases for sugar production from cellulosic biomass using the polypeptide swollenin.
    Type: Application
    Filed: April 29, 2009
    Publication date: June 9, 2011
    Applicant: DANISCO US INC.
    Inventors: Tom Tao Huang, Colin Mitchinson, Rafael F. Sala