Abstract: A patient ventilation interface has a throat body defining a venturi throat that is open to ambient air, a nasal pillow disposed around the venturi throat to define a plenum between the venturi throat and the nasal pillow, a jet nozzle arranged to output ventilation gas into the venturi throat, and a pressure sensing tube having a pressure sensing port positioned to be in fluid communication with the plenum. The nasal pillow may be an integral part of the throat body. An expected error in the sensed patient airway pressure Psense may be corrected by applying a correction factor Pdelta indexed by the sensed patient airway pressure Psense and a jet nozzle flow V?n of the jet nozzle. Delivery of the ventilation gas output by the jet nozzle may be controlled in response to the corrected patient airway pressure.

Abstract: A method of controlling a portable gas source connected to a ventilator includes receiving, via a user interface, a mix setting corresponding to a user-selected percentage of oxygen in a mixture of oxygen and ambient air to be delivered by the ventilator, determining, based on a measured airflow demand on the ventilator, a maximum percentage of oxygen in the mixture at which the mixture still meets the measured airflow demand, and overriding the mix setting with the maximum mix value in response to the maximum mix value being less than the user-selected percentage.

Abstract: A variable throat jet venturi for delivering ventilation gas to a patient includes a jet nozzle, a deformable throat body arranged to receive ventilation gas output by the jet nozzle and defining a gas inlet and a gas outlet, and a housing containing the deformable throat body. The housing may define an entrainment opening which is open to ambient air and a pilot pressure port for pressurizing a plenum between an outer wall of the deformable throat body and an inner wall of the housing. A pilot pressure line may be fluidly coupled to the pilot pressure port. A controller may be programmed to energize the pilot pressure line to constrict the deformable throat body during an exhalation phase of positive end-expiratory pressure (PEEP) therapy.

Abstract: A multifunctional ventilator interface for selectively providing ventilation and continuous oxygen therapy to a patient includes tubing defining a high-pressure gas lumen, a low-pressure gas lumen, and a pressure sensing lumen, a manifold housing defining a gas pathway, a jet pump housing coupled to the manifold housing and defining an entrainment port, a sleeve rotatably engaged to the jet pump housing, and a jet nozzle defining high- and low-pressure jet nozzle outlet ports operative to introduce gas from the high- and low-pressure gas lumens into the gas pathway.

Abstract: An oxygen concentrator includes one or more adsorbent sieve beds operable to remove nitrogen from air to produce concentrated oxygen gas at respective outlets thereof, a product tank fluidly coupled to the respective outlets of the sieve bed(s), a compressor operable to pressurize ambient air, one or more sieve bed flow paths from the compressor to respective inlets of the sieve bed(s), a bypass flow path from the compressor to the product tank that bypasses the sieve bed(s), and a valve unit operable to selectively allow flow of pressurized ambient air from the compressor along the one or more sieve bed flow paths and along the bypass flow path in response to a control signal. The valve unit may be controlled in response to a command issued by a ventilator based on a calculated or estimated total flow of gas and entrained air or % FiO2 of a patient.

Abstract: An oxygen concentrator includes one or more adsorbent sieve beds operable to remove nitrogen from air to produce concentrated oxygen gas at respective outlets thereof, a product tank fluidly coupled to the respective outlets of the sieve bed(s), a compressor operable to pressurize ambient air, one or more sieve bed flow paths from the compressor to respective inlets of the sieve bed(s), a bypass flow path from the compressor to the product tank that bypasses the sieve bed(s), and a valve unit operable to selectively allow flow of pressurized ambient air from the compressor along the one or more sieve bed flow paths and along the bypass flow path in response to a control signal. The valve unit may be controlled in response to a command issued by a ventilator based on a calculated or estimated total flow of gas and entrained air or % FiO2 of a patient.

Abstract: A high-frequency chest wall oscillation (HFCWO) system includes a garment configured to be worn around a chest of a user. At least one fluid pod is housed by the garment and is configured to receive a fluid. The at least one fluid pod includes a housing configured to be pulsated by the fluid.

Abstract: An oxygen concentrator includes one or more adsorbent sieve beds operable to remove nitrogen from air to produce concentrated oxygen gas at respective outlets thereof, a product tank fluidly coupled to the respective outlets of the sieve bed(s), a compressor operable to pressurize ambient air, one or more sieve bed flow paths from the compressor to respective inlets of the sieve bed(s), a bypass flow path from the compressor to the product tank that bypasses the sieve bed(s), and a valve unit operable to selectively allow flow of pressurized ambient air from the compressor along the one or more sieve bed flow paths and along the bypass flow path in response to a control signal. The valve unit may be controlled in response to a command issued by a ventilator based on a calculated or estimated total flow of gas and entrained air or % FiO2 of a patient.

Abstract: A portable oxygen concentrator retrofit system and method in which an existing portable oxygen concentrator may be retrofitted to output an enriched oxygen gas at a flow rate suitable for use in a patient ventilation system without the need for an external source of compressed gas.

Abstract: An oxygen concentrator includes one or more adsorbent sieve beds operable to remove nitrogen from air to produce concentrated oxygen gas at respective outlets thereof, a product tank fluidly coupled to the respective outlets of the sieve bed(s), a compressor operable to pressurize ambient air, one or more sieve bed flow paths from the compressor to respective inlets of the sieve bed(s), a bypass flow path from the compressor to the product tank that bypasses the sieve bed(s), and a valve unit operable to selectively allow flow of pressurized ambient air from the compressor along the one or more sieve bed flow paths and along the bypass flow path in response to a control signal. The valve unit may be controlled in response to a command issued by a ventilator based on a calculated or estimated total flow of gas and entrained air or % FiO2 of a patient.

Abstract: A patient ventilation interface has a throat body defining a venturi throat that is open to ambient air, a nasal pillow disposed around the venturi throat to define a plenum between the venturi throat and the nasal pillow, a jet nozzle arranged to output ventilation gas into the venturi throat, and a pressure sensing tube having a pressure sensing port positioned to be in fluid communication with the plenum. The nasal pillow may be an integral part of the throat body. An expected error in the sensed patient airway pressure Psense may be corrected by applying a correction factor Pdelta indexed by the sensed patient airway pressure Psense and a jet nozzle flow V?n of the jet nozzle. Delivery of the ventilation gas output by the jet nozzle may be controlled in response to the corrected patient airway pressure.

Abstract: A variable throat jet venturi for delivering ventilation gas to a patient includes a jet nozzle, a deformable throat body arranged to receive ventilation gas output by the jet nozzle and defining a gas inlet and a gas outlet, and a housing containing the deformable throat body. The housing may define an entrainment opening which is open to ambient air and a pilot pressure port for pressurizing a plenum between an outer wall of the deformable throat body and an inner wall of the housing. A pilot pressure line may be fluidly coupled to the pilot pressure port. A controller may be programmed to energize the pilot pressure line to constrict the deformable throat body during an exhalation phase of positive end-expiratory pressure (PEEP) therapy.

Abstract: A multifunctional ventilator interface for selectively providing ventilation and continuous oxygen therapy to a patient includes tubing defining a high-pressure gas lumen, a low-pressure gas lumen, and a pressure sensing lumen, a manifold housing defining a gas pathway, a jet pump housing coupled to the manifold housing and defining an entrainment port, a sleeve rotatably engaged to the jet pump housing, and a jet nozzle defining high- and low-pressure jet nozzle outlet ports operative to introduce gas from the high- and low-pressure gas lumens into the gas pathway.

Abstract: An oxygen concentrator includes one or more adsorbent sieve beds operable to remove nitrogen from air to produce concentrated oxygen gas at respective outlets thereof, a product tank fluidly coupled to the respective outlets of the sieve bed(s), a compressor operable to pressurize ambient air, one or more sieve bed flow paths from the compressor to respective inlets of the sieve bed(s), a bypass flow path from the compressor to the product tank that bypasses the sieve bed(s), and a valve unit operable to selectively allow flow of pressurized ambient air from the compressor along the one or more sieve bed flow paths and along the bypass flow path in response to a control signal. The valve unit may be controlled in response to a command issued by a ventilator based on a calculated or estimated total flow of gas and entrained air or % FiO2 of a patient.

Abstract: A portable oxygen concentrator retrofit system and method in which an existing portable oxygen concentrator may be retrofitted to output an enriched oxygen gas at a flow rate suitable for use in a patient ventilation system without the need for an external source of compressed gas.