Patents by Inventor Tomas Hucl

Tomas Hucl has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Functional assay for identification of loss-of-function mutations in genes
    Patent number: 9309511
    Abstract: Provided herein are compositions and methods for assaying the deleteriousness of putative loss-of-function mutations, especially in genes known to be or suspected of being tumor-suppressor genes. The invention includes syngeneic variance libraries and methods of construction and use of syngeneic variance libraries.
    Type: Grant
    Filed: August 28, 2008
    Date of Patent: April 12, 2016
    Assignee: The Johns Hopkins University
    Inventors: Scott E. Kern, Eike Gallmeier, Tomas Hucl
  • FUNCTIONAL ASSAY FOR INDENTIFICATION OF LOSS-OF-FUNCTION MUTATIONS IN GENES
    Publication number: 20100305001
    Abstract: Provided herein are compositions and methods for assaying the deleteriousness of putative loss-of-function mutations, especially in genes known to be or suspected of being tumor-suppressor genes. The invention includes syngeneic variance libraries and methods of construction and use of syngeneic variance libraries.
    Type: Application
    Filed: August 28, 2008
    Publication date: December 2, 2010
    Applicant: The Johns Hopkins University
    Inventors: Scott E. Kern, Eike Gallmeier, Tomas Hucl