Patents by Inventor Tomas Marcelino Hernandez

Tomas Marcelino Hernandez has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Vibrio cholerae vaccine candidates, the methods of their constructing and medicinal preparations derived thereof
    Publication number: 20060233837
    Abstract: A single oral administration dose medicinal preparation is derived from Vibrio cholerae vaccine strains which have a disrupted hemagglutinin protease gene and which are tagged with celA coding functions from Clostridium thermocellum are described. The strains are freeze-dried and derived from non toxigenic parented strains. The medicinal preparation includes lyopectrants. The single dose of 107 to 109 viable cells/single dose provides effective immunization, with antibacterial antibodies present in about 1 day to a peak activity in about 14 days.
    Type: Application
    Filed: April 19, 2005
    Publication date: October 19, 2006
    Inventors: Javier Gomez, Rafael Calzada, Boris Luis Gonzalez, Edgar Diaz, Talena Yamile Perez, Anisia Silva Cabrera, Jorge Antonio Robles, Tomas Marcelino Hernandez