Patents by Inventor Tomas Smejkal

Tomas Smejkal has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240010637
    Abstract: The present invention provides, inter alia, a process for producing a compound of formula (I) wherein the substituents are as defined in claim 1. The present invention further provides intermediate compounds utilised in said process, and methods for producing said intermediate compounds.
    Type: Application
    Filed: August 13, 2021
    Publication date: January 11, 2024
    Applicant: SYNGENTA CROP PROTECTION AG
    Inventors: Raphael DUMEUNIER, Tomas SMEJKAL, Renaud BEAUDEGNIES
  • Publication number: 20230339907
    Abstract: The present invention provides, inter alia, a process for producing a compound of formula (I) wherein the substituents are as defined in claim 1. The present invention further provides intermediate compounds utilised in said process, and methods for producing said intermediate compounds.
    Type: Application
    Filed: August 13, 2021
    Publication date: October 26, 2023
    Applicant: SYNGENTA CROP PROTECTION AG
    Inventors: Tomas SMEJKAL, Raphael DUMEUNIER, Denis GRIBKOV
  • Publication number: 20230109865
    Abstract: The present invention provides, inter alia, a process for producing a compound of formula (I) wherein the substituents are as defined in claim 1, comprising reacting a compound of formula (II) in a suitable reaction medium comprising a desulfurization agent formula (II). The present invention further provides intermediate compounds utilised in said process, and methods for producing said intermediate compounds.
    Type: Application
    Filed: January 20, 2021
    Publication date: April 13, 2023
    Applicant: SYNGENTA CROP PROTECTION AG
    Inventors: Raphael DUMEUNIER, Tomas SMEJKAL, Edouard GODINEAU
  • Patent number: 11369113
    Abstract: The present inventions concerns use of a specific methoxyacrylate compound to control mosquitoes, and vector control products comprising that methoxyacrylate compound, in particular the invention relates to a substrate, to a composition, for controlling mosquitoes, and to a specific methoxyacrylate compound, processes for the synthesis of mosquitocidal methoxyacrylate compounds and new intermediates.
    Type: Grant
    Filed: October 24, 2018
    Date of Patent: June 28, 2022
    Assignee: Syngenta Participations AG
    Inventors: Ottmar Franz Hueter, Mark Hoppe, Tomas Smejkal, Raphael Dumeunier, Nicolas Fedou, Edouard Godineau, Philip Wege, Peter Maienfisch
  • Publication number: 20220106263
    Abstract: The present invention relates to novel processes for the enantioselective iridium-catalysed hydrogenation of oximes and oxime ethers to provide compounds of formula (II) and salts thereof formula (I) and (II).
    Type: Application
    Filed: November 1, 2019
    Publication date: April 7, 2022
    Applicant: SYNGENTA CROP PROTECTION AG
    Inventors: Tomas SMEJKAL, Nicolai CRAMER, Josep MAS-ROSELLO
  • Publication number: 20210387173
    Abstract: The present invention relates to a novel process for the iridium-catalysed hydrogenation of oximes. The invention also relates to novel iridium catalysts for use in the iridium-catalysed hydrogenation of oximes and to processes of preparation of these catalysts. The invention further relates to the use of the novel iridium catalysts in ionic hydrogenation of other unsaturated substrates.
    Type: Application
    Filed: November 1, 2019
    Publication date: December 16, 2021
    Applicant: SYNGENTA CROP PROTECTION AG
    Inventor: Tomas SMEJKAL
  • Patent number: 11053188
    Abstract: The present invention relates to a process for the preparation of enantiomerically and diastereomerically enriched cyclobutane amines and amides by reacting (a) cyclopropylcarbonitrile to a cyclopropylcarbaldehyde, (b) further reacting to a cyclobutanone, or (d?) further reacting to an enamide, (c) further reacting to enantiomerically and diastereomerically enriched cyclobutane amines, or (d) further reacting to an enamide and (e) to an enantiomerically and diastereomerically enriched cyclobutylamide to obtain (f) an enantiomerically and diastereomerically enriched cyclobutane amine, and (g) further reacting to an enantiomerically and diastereomerically enriched cyclobutane amide.
    Type: Grant
    Filed: November 14, 2018
    Date of Patent: July 6, 2021
    Assignee: SYNGENTA PARTICIPATIONS AG
    Inventors: Raphael Dumeunier, Tomas Smejkal, Brijnandan Premnath Mishra, Vijayagopal Raman Gopalsamuthiram, Edouard Godineau, Anthony Cornelius O'Sullivan
  • Patent number: 10961248
    Abstract: Compounds of formula (I), wherein the substituents are as defined in claim 1, and the agrochemically acceptable salts, stereoisomers, enantiomers, tautomers and N-oxides of those compounds, can be used as insecticides and can be prepared in a manner known per se.
    Type: Grant
    Filed: November 24, 2017
    Date of Patent: March 30, 2021
    Assignee: SYNGENTA PARTICIPATIONS AG
    Inventors: Andrew Edmunds, Michel Muehlebach, Pierre Joseph Marcel Jung, Sebastian Rendler, Vikas Sikervar, Girish Rawal, Indira Sen, Régis Jean Georges Mondiere, Tomas Smejkal, Myriem El Qacemi, Denis Gribkov
  • Publication number: 20200407311
    Abstract: The present invention relates to a process for the preparation of enantiomerically and diastereomerically enriched cyclobutane amines and amides by reacting (a) cyclopropylcarbonitrile to a cyclopropylcarbaldehyde, (b) further reacting to a cyclobutanone, or (d) further reacting to an enamide, 5 (c) further reacting to enantiomerically and diastereomerically enriched cyclobutane amines, or (d) further reacting to an enamide and (e) to an enantiomerically and diastereomerically enriched cyclobutylamide to obtain (f) an enantiomerically and diastereomerically enriched cyclobutane amine, and (g) further reacting to an enantiomerically and diastereomerically enriched cyclobutane amide.
    Type: Application
    Filed: November 14, 2018
    Publication date: December 31, 2020
    Applicant: SYNGENTA PARTICIPATIONS AG
    Inventors: Raphael DUMEUNIER, Tomas SMEJKAL, Brijnandan Premnath MISHRA, Vijayagopal Raman GOPALSAMUTHIRAM, Edouard GODINEAU, Anthony Cornelius O'SULLIVAN
  • Publication number: 20200315175
    Abstract: The present inventions concerns use of a specific methoxyacrylate compound to control mosquitoes, and vector control products comprising that methoxyacrylate compound, in particular the invention relates to a substrate, to a composition, for controlling mosquitoes, and to a specific methoxyacrylate compound, processes for the synthesis of mosquitocidal methoxyacrylate compounds and new intermediates.
    Type: Application
    Filed: October 24, 2018
    Publication date: October 8, 2020
    Applicant: Syngenta Participations AG
    Inventors: Ottmar Franz HUETER, Mark HOPPE, Tomas SMEJKAL, Raphael DUMEUNIER, Nicolas FEDOU, Edouard GODINEAU, Philip WEGE, Peter MAIENFISCH
  • Publication number: 20190330204
    Abstract: The present invention relates to a process for the preparation of a compound of formula (IX) wherein R1, R2A, R2B, R3, R4, R5 and R6 are as defined in the specification. Furthermore, the present invention also relates to reduction of the compound of formula (IX) to produce a compound of formula (I).
    Type: Application
    Filed: April 24, 2017
    Publication date: October 31, 2019
    Applicant: SYNGENTA PARTICIPATIONS AG
    Inventors: Rupesh PATRE, Tomas SMEJKAL
  • Publication number: 20190322675
    Abstract: Compounds of formula (I), wherein the substituents are as defined in claim 1, and the agrochemically acceptable salts, stereoisomers, enantiomers, tautomers and N-oxides of those compounds, can be used as insecticides and can be prepared in a manner known per se.
    Type: Application
    Filed: November 24, 2017
    Publication date: October 24, 2019
    Applicant: SYNGENTA PARTICIPATIONS AG
    Inventors: Andrew EDMUNDS, Michel MUEHLEBACH, Pierre Joseph Marcel JUNG, Sebastian RENDLER, Vikas SIKERVAR, Girish RAWAL, Indira SEN, Régis Jean Georges MONDIERE, Tomas SMEJKAL, Sujit Kumar GHORAI, Denis GRIBKOV
  • Patent number: 10093672
    Abstract: A process for making certain spiroheterocyclic pyrrolidine dione derivatives.
    Type: Grant
    Filed: April 20, 2018
    Date of Patent: October 9, 2018
    Assignee: SYNGENTA PARTICIPATIONS AG
    Inventors: Edouard Godineau, Tomas Smejkal, Sophie Pelletier, Michel Muehlebach, Régis Jean Georges Mondiere, Helmars Smits, Jochen Weckesser, Alan James Robinson
  • Publication number: 20180237437
    Abstract: A process for making certain spiroheterocyclic pyrrolidine dione derivatives.
    Type: Application
    Filed: April 20, 2018
    Publication date: August 23, 2018
    Applicant: SYNGENTA PARTICIPATIONS AG
    Inventors: Edouard Godineau, Tomas Smejkal, Sophie Pelletier, Michel Muehlebach, Régis Jean Georges Mondiere, Helmars Smits, Jochen Weckesser, Alan James Robinson
  • Patent number: 9969734
    Abstract: A process for making certain spiroheterocyclic pyrrolidine dione derivatives.
    Type: Grant
    Filed: July 11, 2014
    Date of Patent: May 15, 2018
    Assignee: Syngenta Participations AG
    Inventors: Edouard Godineau, Tomas Smejkal, Sophie Pelletier, Michel Muehlebach, Regis Jean Georges Mondiere, Helmars Smits, Jochen Weckesser, Alan James Robinson
  • Patent number: 9867371
    Abstract: Compounds of the formula (I), in which the substituents are as defined in claim 1, are suitable for use as nematicides.
    Type: Grant
    Filed: July 1, 2014
    Date of Patent: January 16, 2018
    Assignee: Syngenta Participations AG
    Inventors: Anthony Cornelius O'Sullivan, Regis Jean Georges Mondiere, Olivier Loiseleur, Tomas Smejkal, Torsten Luksch, Andre Jeanguenat, Raphael Dumeunier, Edouard Godineau, Thomas Pitterna
  • Patent number: 9815829
    Abstract: The present invention relates to a process for the preparation of a compound of formula (I) wherein A1 and A2 are C—H, or one of A1 and A2 is C—H and the other is N; R1 is C1-C4alkyl, C1-C4haloalkyl or C3-C6cycloalkyl; each R2 is independently bromo, chloro, fluoro or trifluoromethyl; R3 is hydrogen; R4 is hydrogen, halogen, methyl, halomethyl or cyano; or R3 and R4 together form a bridging 1,3-butadiene group; R5 is chlorodifluoromethyl or trifluoromethyl; n is 2 or 3; by reacting a compound of formula (II) wherein A1, A2, R1, R2, R3, R4, R5 and n is as defined under formula (I) above, with hydroxylamine, a base and a chiral catalyst, characterized in that the chiral catalyst is a dimeric chiral catalyst of formula (III) wherein R6, R7, R8, R9, R10 and X are as defined in claim 1.
    Type: Grant
    Filed: August 4, 2015
    Date of Patent: November 14, 2017
    Assignee: Syngenta Participations AG
    Inventors: Tomas Smejkal, Helmars Smits
  • Patent number: 9815803
    Abstract: The present invention relates to processes for the preparation of substituted cycloserine compounds of formula (I) wherein R1 is C1-C8alkyl, C1-C8haloalkyl, C3-C6 cycloalkyl, aryl or aryl substituted by one to five R11, or aryl-C1-C4alkylene or aryl-C1-C4alkylene substituted by one to five R11; and each R11 is independently C1-C4alkyl, C1-C4haloalkyl, C1-C4alkoxy, C1-C4haloalkoxy, cyano or halogen; The invention also relates to intermediates produced by the processes. Compounds of formula (I) are useful intermediates for the production of compounds in the agricultural and pharmaceutical fields.
    Type: Grant
    Filed: April 3, 2017
    Date of Patent: November 14, 2017
    Assignee: Syngenta Participations AG
    Inventors: Tomas Smejkal, Helmars Smits, Christian Lothschuetz, Miroslav Terinek
  • Publication number: 20170217953
    Abstract: The present invention relates to a process for the preparation of a compound of formula (I) wherein A1 and A2 are C—H, or one of A1 and A2 is C—H and the other is N; R1 is C1-C4alkyl, C1-C4haloalkyl or C3-C6cycloalkyl; each R2 is independently bromo, chloro, fluoro or trifluoromethyl; R3 is hydrogen; R4 is hydrogen, halogen, methyl, halomethyl or cyano; or R3 and R4 together form a bridging 1,3-butadiene group; R5 is chlorodifluoro-methyl or trifluoromethyl; n is 2 or 3; by reacting a compound of formula (II) wherein A1, A2, R1, R2, R3, R4, R5 and n is as defined under formula (I) above, with hydroxylamine, a base and a chiral catalyst, characterized in that the chiral catalyst is a dimeric chiral catalyst of formula (III) wherein R6, R7, R8, R9, R10 and X are as defmed in claim 1.
    Type: Application
    Filed: August 4, 2015
    Publication date: August 3, 2017
    Applicant: Syngenta Participations AG
    Inventors: Tomas SMEJKAL, Helmars SMITS
  • Publication number: 20170204072
    Abstract: The present invention relates to processes for the preparation of substituted cycloserine compounds of formula (I) wherein R1 is C1-C8alkyl, C1-C8haloalkyl, C3-C6 cycloalkyl, aryl or aryl substituted by one to five R11, or aryl-C1-C4alkylene or aryl-C1-C4alkylene substituted by one to five R11; and each R11 is independently C1-C4alkyl, C1-C4haloalkyl, C1-C4alkoxy, C1-C4haloalkoxy, cyano or halogen; The invention also relates to intermediates produced by the processes. Compounds of formula (I) are useful intermediates for the production of compounds in the agricultural and pharmaceutical fields.
    Type: Application
    Filed: April 3, 2017
    Publication date: July 20, 2017
    Applicant: Syngenta Participations AG
    Inventors: Tomas SMEJKAL, Helmars SMITS, Christian LOTHSCHUETZ, Miroslav TERINEK