Patents by Inventor Tomasz Heyduk

Tomasz Heyduk has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Molecular biosensors capable of signal amplification
    Patent number: 10416154
    Abstract: The present invention provides molecular biosensors capable of signal amplification, and methods of using the molecular biosensors to detect the presence of a target molecule.
    Type: Grant
    Filed: September 21, 2017
    Date of Patent: September 17, 2019
    Assignees: Mediomics LLC, Saint Louis University
    Inventors: Yie-Hwa Chang, Ling Tian, Tomasz Heyduk
  • Biosensor for detecting multiple epitopes on a target
    Patent number: 10416157
    Abstract: The present invention encompasses a method for detecting a target comprising a repeating epitope.
    Type: Grant
    Filed: June 5, 2017
    Date of Patent: September 17, 2019
    Assignees: Saint Louis University, Mediomics, LLC
    Inventors: Tomasz Heyduk, Ling Tian
  • Methods for the selection of aptamers
    Patent number: 9951376
    Abstract: The present invention generally relates to methods for selecting aptamers. More specifically, the invention provides methods for the selection of at least one aptamer for use in combination with another epitope binding agent such as another aptamer, an antibody, or a double stranded nucleic acid. The invention also encompasses methods for simultaneously selecting at least two aptamers that each recognize distinct epitopes on a target molecule.
    Type: Grant
    Filed: January 6, 2015
    Date of Patent: April 24, 2018
    Assignee: Saint Louis University
    Inventors: Tomasz Heyduk, Ewa Heyduk
  • MOLECULAR BIOSENSORS CAPABLE OF SIGNAL AMPLIFICATION
    Publication number: 20180011087
    Abstract: The present invention provides molecular biosensors capable of signal amplification, and methods of using the molecular biosensors to detect the presence of a target molecule.
    Type: Application
    Filed: September 21, 2017
    Publication date: January 11, 2018
    Applicants: Mediomics LLC, Saint Louis University
    Inventors: Yie-Hwa Chang, Ling Tian, Tomasz Heyduk
  • Molecular biosensors capable of signal amplification
    Patent number: 9797892
    Abstract: The present invention provides molecular biosensors capable of signal amplification, and methods of using the molecular biosensors to detect the presence of a target molecule.
    Type: Grant
    Filed: May 22, 2015
    Date of Patent: October 24, 2017
    Assignees: SAINT LOUIS UNIVERSITY, MEDIOMICS LLC
    Inventors: Yie-Hwa Chang, Ling Tian, Tomasz Heyduk
  • BIOSENSOR FOR DETECTING MULTIPLE EPITOPES ON A TARGET
    Publication number: 20170269082
    Abstract: The present invention encompasses a method for detecting a target comprising a repeating epitope.
    Type: Application
    Filed: June 5, 2017
    Publication date: September 21, 2017
    Inventors: Tomasz Heyduk, Ling Tian
  • Biosensor for detecting multiple epitopes on a target
    Patent number: 9671403
    Abstract: The present invention encompasses a method for detecting a target comprising a repeating epitope.
    Type: Grant
    Filed: March 30, 2015
    Date of Patent: June 6, 2017
    Assignees: MEDIOMICS, LLC, SAINT LOUIS UNIVERSITY
    Inventors: Tomasz Heyduk, Ling Tian
  • Biosensors for detecting macromolecules and other analytes
    Patent number: 9618505
    Abstract: The invention generally provides two-component molecular biosensors. In particular, the invention provides molecular biosensors having peptide epitope binding agents that bind a target antibody. The molecular biosensors are useful in several methods including in the identification and quantification of target molecules.
    Type: Grant
    Filed: February 16, 2015
    Date of Patent: April 11, 2017
    Assignee: MEDIOMICS, LLC
    Inventors: Tomasz Heyduk, Ling Tian, Rongsheng E. Wang, Yie-Hwa Chang
  • MOLECULAR BIOSENSORS CAPABLE OF SIGNAL AMPLIFICATION
    Publication number: 20150253315
    Abstract: The present invention provides molecular biosensors capable of signal amplification, and methods of using the molecular biosensors to detect the presence of a target molecule.
    Type: Application
    Filed: May 22, 2015
    Publication date: September 10, 2015
    Inventors: Yie-Hwa Chang, Ling Tian, Tomasz Heyduk
  • BIOSENSOR FOR DETECTING MULTIPLE EPITOPES ON A TARGET
    Publication number: 20150226739
    Abstract: The present invention encompasses a method for detecting a target comprising a repeating epitope.
    Type: Application
    Filed: March 30, 2015
    Publication date: August 13, 2015
    Inventors: Tomasz Heyduk, Ling Tian
  • BIOSENSORS FOR DETECTING MACROMOLECULES AND OTHER ANALYTES
    Publication number: 20150219668
    Abstract: The invention generally provides three-component molecular biosensors. The molecular biosensors are useful in several methods including in the identification and quantification of target molecules.
    Type: Application
    Filed: February 16, 2015
    Publication date: August 6, 2015
    Applicants: MEDIOMICS LLC, SAINT LOUIS UNIVERSITY
    Inventors: Tomasz Heyduk, Ling Tian, Rongsheng E. Wang, Yie-Hwa Chang
  • METHODS FOR THE SELECTION OF APTAMERS
    Publication number: 20150191779
    Abstract: The present invention generally relates to methods for selecting aptamers. More specifically, the invention provides methods for the selection of at least one aptamer for use in combination with another epitope binding agent such as another aptamer, an antibody, or a double stranded nucleic acid. The invention also encompasses methods for simultaneously selecting at least two aptamers that each recognize distinct epitopes on a target molecule.
    Type: Application
    Filed: January 6, 2015
    Publication date: July 9, 2015
    Inventors: Tomasz Heyduk, Ewa Heyduk
  • Molecular biosensors capable of signal amplification
    Patent number: 9040287
    Abstract: The present invention provides molecular biosensors capable of signal amplification, and methods of using the molecular biosensors to detect the presence of a target molecule.
    Type: Grant
    Filed: February 11, 2011
    Date of Patent: May 26, 2015
    Assignees: Mediomics, LLC, Saint Louis University
    Inventors: Yie-Hwa Chang, Ling Tian, Tomasz Heyduk
  • Biosensor for detecting multiple epitopes on a target
    Patent number: 8993245
    Abstract: The present invention encompasses a method for detecting a target comprising a repeating epitope.
    Type: Grant
    Filed: November 19, 2009
    Date of Patent: March 31, 2015
    Assignees: Mediomics, LLC, Saint Louis University
    Inventors: Tomasz Heyduk, Ling Tian
  • Three-component biosensors for detecting macromolecules and other analytes
    Patent number: 8956857
    Abstract: The invention generally provides three-component molecular biosensors. The molecular biosensors are useful in several methods including in the identification and quantification of target molecules.
    Type: Grant
    Filed: December 27, 2012
    Date of Patent: February 17, 2015
    Assignees: Mediomics, LLC, Saint Louis University
    Inventors: Tomasz Heyduk, Ling Tian, Rongsheng E. Wang, Yie-Hwa Chang
  • Methods for the selection of aptamers
    Patent number: 8945840
    Abstract: The present invention generally relates to methods for selecting aptamers. More specifically, the invention provides methods for the selection of at least one aptamer for use in combination with another epitope binding agent such as another aptamer, an antibody, or a double stranded nucleic acid. The invention also encompasses methods for simultaneously selecting at least two aptamers that each recognize distinct epitopes on a target molecule.
    Type: Grant
    Filed: May 16, 2006
    Date of Patent: February 3, 2015
    Assignee: Saint Louis University
    Inventors: Tomasz Heyduk, Ewa Heyduk
  • THREE-COMPONENT BIOSENSORS FOR DETECTING MACROMOLECULES AND OTHER ANALYTES
    Publication number: 20140248710
    Abstract: The invention generally provides three-component molecular biosensors. The molecular biosensors are useful in several methods including in the identification and quantification of target molecules.
    Type: Application
    Filed: December 27, 2012
    Publication date: September 4, 2014
    Applicants: Mediomics LLC, Saint Louis University
    Inventors: Tomasz Heyduk, Ling Tian, Rongsheng E. Wang, Yie-Hwa Chang
  • Biosensors for detecting macromolecules and other analytes
    Patent number: 8592202
    Abstract: The invention generally provides molecular biosensors. In particular, the invention provides molecular biosensors having one or more aptamers. The molecular biosensors are useful in several methods including in the identification and quantification of target molecules.
    Type: Grant
    Filed: December 6, 2010
    Date of Patent: November 26, 2013
    Assignee: Saint Louis University
    Inventors: Tomasz Heyduk, Ewa Heyduk, Eric Knoll
  • Three-component biosensors for detecting macromolecules and other analytes
    Patent number: 8431388
    Abstract: The invention generally provides three-component molecular biosensors. The molecular biosensors are useful in several methods including in the identification and quantification of target molecules.
    Type: Grant
    Filed: July 6, 2010
    Date of Patent: April 30, 2013
    Assignee: Saint Louis University
    Inventor: Tomasz Heyduk
  • MOLECULAR BIOSENSORS CAPABLE OF SIGNAL AMPLIFICATION
    Publication number: 20130034846
    Abstract: The present invention provides molecular biosensors capable of signal amplification, and methods of using the molecular biosensors to detect the presence of a target molecule.
    Type: Application
    Filed: February 11, 2011
    Publication date: February 7, 2013
    Applicants: MEDIOMICS LLC, SAINT LOUIS UNIVERSITY
    Inventors: Yie-Hwa Chang, Ling Tian, Tomasz Heyduk