Patents by Inventor Tomaz Mesar

Tomaz Mesar has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Synthesis of statins
    Patent number: 8471045
    Abstract: The process for the synthesis of statins featuring the use of an early intermediate (4R,6S)-6-(dialkoxymethyl)tetrahydro-2H-pyran-2,4-diol which already possesses the desired stereochemistry corresponding to the final statin.
    Type: Grant
    Filed: March 12, 2012
    Date of Patent: June 25, 2013
    Assignee: Lek Pharmaceuticals D.D.
    Inventors: Zdenko Casar, Tomaz Mesar, Gregor Kopitar, Peter Mrak, Matej Oslaj
  • SYNTHESIS OF STATINS
    Publication number: 20120196333
    Abstract: The process for the synthesis of statins featuring the use of an early intermediate (4R,6S)-6-(dialkoxymethyl)tetrahydro-2H-pyran-2,4-diol which already possesses the desired stereochemistry corresponding to the final statin.
    Type: Application
    Filed: March 12, 2012
    Publication date: August 2, 2012
    Applicant: LEK PHARMACEUTICALS D.D.
    Inventors: ZDENKO CASAR, TOMAZ MESAR, GREGOR KOPITAR, PETER MRAK, MATEJ OSLAJ
  • Synthesis of statins
    Patent number: 8183397
    Abstract: The process for the synthesis of statins featuring the use of an early intermediate (4R,6S)-6-(dialkoxymethyl)tetrahydro-2H-pyran-2,4-diol which already possesses the desired stereochemistry corresponding to the final statin.
    Type: Grant
    Filed: April 2, 2008
    Date of Patent: May 22, 2012
    Assignee: Lek Pharmaceuticals D.D.
    Inventors: Zdenko Casar, Tomaz Mesar, Gregor Kopitar, Peter Mrak, Matej Oslaj
  • SYNTHESIS OF STATINS
    Publication number: 20110178295
    Abstract: The process for the synthesis of statins featuring the use of an early intermediate (4R,6S)-6-(dialkoxymethyl)tetrahydro-2H-pyran-2,4-diol which already possesses the desired stereochemistry corresponding to the final statin.
    Type: Application
    Filed: April 2, 2008
    Publication date: July 21, 2011
    Applicant: LEK PHARMACEUTICALS D.D.
    Inventors: Zdenko Casar, Tomaz Mesar, Gregor Kopitar, Peter Mrak, Matej Oslaj
  • Synthesis of 2-Methyl-4-(4-Methyl-1-Piperazinly)-10H-Thieno(2,3-B) (1,5) Benzodiazepine and Salts Thereof
    Publication number: 20080161557
    Abstract: The invention belongs to the field of organic chemistry and relates to a new process for the purification of olanzapine comprising preparation of acid addition salts of olanzapine and transformation thereof into a pharmaceutically acceptable pure and discoloured final product. The present invention also relates to new processes for the preparation of pure olanzapine.
    Type: Application
    Filed: March 17, 2005
    Publication date: July 3, 2008
    Applicant: LEK PHARMACEUTICALS D.D.
    Inventors: Tomaz Mesar, Anton Copar, Hubert Sturm, Johannes Ludescher