Patents by Inventor Tomiki Hashiyama

Tomiki Hashiyama has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Baccatin derivatives and processes for preparing the same
    Patent number: 5677470
    Abstract: Disclosed are 13.alpha.-(3-substituted-2-hydroxypropionyloxy)baccatin compounds represented by the formula: ##STR1## wherein R.sup.1 represents a lower alkanoyl group or a protective group for hydroxy group; R.sup.2 represents a protective group for hydroxy group; R.sup.3 represents a lower alkanoyl group; R.sup.4 represents a substituted or unsubstituted benzoyl group; X represents a substituted or unsubstituted aryl group, a substituted or unsubstituted lower alkenyl group, or a substituted or unsubstituted lower alkynyl group; and A' represents a halogen atom, azido group or amino group,and processes for preparing the same.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: October 14, 1997
    Assignee: Tanabe Seiyaku Co., Ltd.
    Inventors: Kenji Tsujihara, Tomiki Hashiyama, Naoyuki Harada, Kunihiko Ozaki, Motoaki Ohashi, Noriyuki Nakanishi, Tetsuo Yamaguchi
  • Baccatin derivatives and processes for preparing the same
    Patent number: 5608073
    Abstract: A compound represented by the formula [I]: ##STR1## wherein R.sup.3 represents a lower alkanoyl group; R.sup.4 represents a substituted or unsubstituted benzoyl group; ring A represents a substituted or unsubstituted cyclopropane ring; X represents a single bond or a group represented by --O--,--S-- or --NH--, R represents a substituted or unsubstituted lower alkyl group (wherein said lower alkyl group may have a cycloalkyl moiety), a substituted or unsubstituted aryl group or a substituted or unsubstituted aromatic heterocyclic group; E represents hydrogen atom or a group represented by --CO(CH.sub.2).sub.
    Type: Grant
    Filed: July 1, 1996
    Date of Patent: March 4, 1997
    Assignee: Tanabe Seiyaku Co., Ltd.
    Inventors: Kenji Tsujihara, Tomiki Hashiyama, Motoaki Ohashi, Noriyuki Nakanishi
  • Baccatin derivatives and processes for preparing the same
    Patent number: 5589502
    Abstract: A compound represented by the formula [I]: ##STR1## wherein R.sup.3 represents a lower alkanoyl group; R.sup.4 represents a substituted or unsubstituted benzoyl group; ring A represents a substituted or unsubstituted cyclopropane ring; X represents a single bond or a group represented by --O--, --S-- or --NH--; R represents a substituted or unsubstituted lower alkyl group (wherein said lower alkyl group may have a cycloalkyl moiety), a substituted or unsubstituted aryl group or a substituted or unsubstituted aromatic heterocyclic group; E represents hydrogen atom or a group represented by --CO(CH.sub.2).sub.
    Type: Grant
    Filed: November 15, 1995
    Date of Patent: December 31, 1996
    Assignee: Tanabe Seiyaku Co., Ltd.
    Inventors: Kenji Tsujihara, Tomiki Hashiyama, Motoaki Ohashi, Noriyuki Nakanishi
  • Process for preparing threo-2-hydroxy-3-(4-methoxyphenyl)-3-(2-nitrophenylthio)-propionic ester
    Patent number: 4420628
    Abstract: A threo-2-hydroxy-3-(4-methoxyphenyl)-3-(2-nitrophenylthio)propionic ester of the formula: ##STR1## wherein R is an ester residue, is prepared by condensing a trans-3-(4-methoxyphenyl)glycidic ester of the formula: ##STR2## wherein R is the same as defined above, with 2-nitrothiophenol in the presence of a Lewis acid.
    Type: Grant
    Filed: February 8, 1982
    Date of Patent: December 13, 1983
    Assignee: Tanabe Seiyaku Co., Ltd.
    Inventors: Hirozumi Inoue, Tomiki Hashiyama