Patents by Inventor Tomislav Caval

Tomislav Caval has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods for Middle Down Antibody Characterization
    Publication number: 20230221333
    Abstract: This disclosure relates to new methods for antibody characterization sequencing, such as middle down antibody characterization and sequencing, for example, for de novo antibody sequencing, identifying known antibodies in a sample, or verifying the sequence of antibodies in a sample. In some embodiments, the methods involve exposing antibodies to cathepsin D, cathepsin L, and/or cathepsin D and L, followed by mass spectrometry and sequence identification and deconvolution.
    Type: Application
    Filed: January 17, 2023
    Publication date: July 13, 2023
    Applicants: Genentech, Inc., Universiteit Utrecht Holding B.V.
    Inventors: Wendy Noel Sandoval, Tomislav Caval, Albert J.R. Heck, Elizabeth Sara Hecht