Patents by Inventor Tommaso Angelini

Tommaso Angelini has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for the industrial synthesis of lurasidone
    Patent number: 9518047
    Abstract: Disclosed is a process for the industrial synthesis of Lurasidone from (1R,2R)-cyclohexane-1,2-diyldimethanol (1), 3-(piperazin-1-yl)benzo[d]isothiazole (3) and (3aR,4R,7R,7aS)-3a,4,7,7a-tetrahydro-4,7-methanoisobenzofuran-1,3-dione (6).). Said process is optimised to obtain Lurasidone with high yields and high purities by preparing highly pure synthesis intermediates, using critical raw materials and reagents in amounts close to the stoichiometric amounts, increasing productivity and reducing the costs and environmental impact of the process.
    Type: Grant
    Filed: October 16, 2014
    Date of Patent: December 13, 2016
    Assignee: PROCOS S.P.A.
    Inventors: Tommaso Angelini, Piergiorgio Bettoni, Jacopo Roletto, Paolo Paissoni
  • PROCESS FOR THE INDUSTRIAL SYNTHESIS OF LURASIDONE
    Publication number: 20160237077
    Abstract: Disclosed is a process for the industrial synthesis of Lurasidone from (1R,2R)-cyclohexane-1,2-diyldimethanol (1), 3-(piperazin-1-yl)benzo[d]isothiazole (3) and (3aR,4R,7R,7aS)-3a,4,7,7a-tetrahydro-4,7-methanoisobenzofuran-1,3-dione (6).). Said process is optimised to obtain Lurasidone with high yields and high purities by preparing highly pure synthesis intermediates, using critical raw materials and reagents in amounts close to the stoichiometric amounts, increasing productivity and reducing the costs and environmental impact of the process.
    Type: Application
    Filed: October 16, 2014
    Publication date: August 18, 2016
    Applicant: PROCOS S.P.A.
    Inventors: Tommaso Angelini, Piergiorgio Bettoni, Jacopo Roletto, Paolo Paissoni