Patents by Inventor Tommaso Nastasi

Tommaso Nastasi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 7425615
    Abstract: The present invention relates to a muscle-specific protein, Ozz, and nucleic acids encoding the protein, that regulates development and function of muscle cells. The invention further relates to muscle-specific regulated expression of the protein, and of heterologous genes under control of the same regulatory sequences. In a specific example, a murine Ozz protein of 285 amino acids is preferentially expressed by a 1.0 kb mRNA in heart and skeletal muscle. This protein shares significant homology with neuralized proteins, and associates with a number of muscle proteins, including ?-catenin.
    Type: Grant
    Filed: May 23, 2006
    Date of Patent: September 16, 2008
    Assignee: St. Jude Children's Research Hospital
    Inventors: Alessandra D'azzo, Antonella Bongiovanni, Tommaso Nastasi
  • Publication number: 20060236410
    Abstract: The present invention relates to a muscle-specific protein, Ozz, and nucleic acids encoding the protein, that regulates development and function of muscle cells. The invention further relates to muscle-specific regulated expression of the protein, and of heterologous genes under control of the same regulatory sequences. In a specific example, a murine Ozz protein of 285 amino acids is preferentially expressed by a 1.0 kb mRNA in heart and skeletal muscle. This protein shares significant homology with neuralized proteins, and associates with a number of muscle proteins, including ?-catenin.
    Type: Application
    Filed: May 23, 2006
    Publication date: October 19, 2006
    Applicant: St. Jude Children's Research Hospital
    Inventors: Alessandra D'Azzo, Antonella Bongiovanni, Tommaso Nastasi
  • Patent number: 7074908
    Abstract: The present invention relates to a muscle-specific protein, Ozz, and nucleic acids encoding the protein, that regulates development and function of muscle cells. The invention further relates to muscle-specific regulated expression of the protein, and of heterologous genes under control of the same regulatory sequences. In a specific example, a murine Ozz protein of 285 amino acids is preferentially expressed by a 1.0 kb mRNA in heart and skeletal muscle. This protein shares significant homology with neuralized proteins, and associates with a number of muscle proteins, including ?-catenin.
    Type: Grant
    Filed: October 29, 2001
    Date of Patent: July 11, 2006
    Assignee: St. Jude Children's Research Hospital
    Inventors: Alessandra D'Azzo, Antonella Bongiovanni, Tommaso Nastasi
  • Publication number: 20020099173
    Abstract: The present invention relates to a muscle-specific protein, Ozz, and nucleic acids encoding the protein, that regulates development and function of muscle cells. The invention further relates to muscle-specific regulated expression of the protein, and of heterologous genes under control of the same regulatory sequences. In a specific example, a murine Ozz protein of 285 amino acids is preferentially expressed by a 1.0 kb mRNA in heart and skeletal muscle. This protein shares significant homology with neuralized proteins, and associates with a number of muscle proteins, including &bgr;-catenin.
    Type: Application
    Filed: October 29, 2001
    Publication date: July 25, 2002
    Applicant: St. Jude Children's Research Hospital
    Inventors: Alessandra D'Azzo, Antonella Bongiovanni, Tommaso Nastasi