Abstract: Provided herein is a method for the isolation or removal of a cellular component from a cell that comprises the steps of applying a pulse of nanoparticles to the cell, allowing the nanoparticles to traffic through the cell for a period of time sufficient to allow the nanoparticles locate to and interact with the cellular component to be isolated, and separation of the nanoparticles and isolated cellular component from the cell.

Abstract: A method for producing an opto cable with a central strain relief core, a glue layer on the surface of the core, a first array of optofibre-containing tubular elements bonded to the core by the glue layer, and a porous filing material filling the space between the tubular elements and the glue on the surface of the strain relief core. At least a second array of optofibre-containing tubular elements is bonded to the first array by surrounding the first array of tubular elements and the filling material with a layer of glue which bonds the second array of tubular elements to the structure. Filling material is added between the tubular elements of the second array and the layer of glue. Additional concentric arrays of glue layers, tubular elements, and filling material can be added in the same manner. A casing surrounds the outermost concentric array of tubular elements.

Abstract: The invention concerns the use of a coiled coil protein which is capable of forming a homodimer which dissociates into monomers on change of temperature, in a method of isolating a ligand or desired protein from a sample. A method of isolating a ligand which binds to the coiled coil protein is described as well as methods of isolating a desired protein which is tagged with a coiled coil protein or a ligand which binds to a coiled coil protein, or is tagged with a coiled coil protein monomer.