Patents by Inventor Tommy Lai
Tommy Lai has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20230045776Abstract: Described herein are tetrahydro-pyrido[3,4-b]indol-1-yl compounds with estrogen receptor modulation activity or function having the Formula I structure: and stereoisomers, tautomers, or pharmaceutically acceptable salts thereof, and with the substituents and structural features described herein. Also described are pharmaceutical compositions and medicaments that include the Formula I compounds, as well as methods of using such estrogen receptor modulators, alone and in combination with other therapeutic agents, for treating diseases or conditions that are mediated or dependent upon estrogen receptors.Type: ApplicationFiled: February 25, 2021Publication date: February 9, 2023Applicant: Genentech, Inc.Inventors: Sharada Labadie, Jun Liang, Daniel Fred Ortwine, Xiaojing Wang, Jason Zbieg, Birong Zhang, Simon Charles Goodacre, Nicholas Charles Ray, Jun Li, Tommy Lai, Jiangpeng Liao, Zhiguo Liu, John Wai, Tao Wang
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Publication number: 20210236473Abstract: Described herein are tetrahydro-pyrido[3,4-b]indol-1-yl compounds with estrogen receptor modulation activity or function having the Formula I structure: and stereoisomers, tautomers, or pharmaceutically acceptable salts thereof, and with the substituents and structural features described herein. Also described are pharmaceutical compositions and medicaments that include the Formula I compounds, as well as methods of using such estrogen receptor modulators, alone and in combination with other therapeutic agents, for treating diseases or conditions that are mediated or dependent upon estrogen receptors.Type: ApplicationFiled: February 25, 2021Publication date: August 5, 2021Applicant: Genentech, Inc.Inventors: Sharada Labadie, Jun Liang, Daniel Fred Ortwine, Xiaojing Wang, Jason Zbieg, Birong Zhang, Simon Charles Goodacre, Nicholas Charles Ray, Jun Li, Tommy Lai, Jiangpeng Liao, Zhiguo Liu, John Wai, Tao Wang
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Patent number: 10966963Abstract: Described herein are tetrahydro-pyrido[3,4-b]indol-1-yl compounds with estrogen receptor modulation activity or function having the Formula I structure: and stereoisomers, tautomers, or pharmaceutically acceptable salts thereof, and with the substituents and structural features described herein. Also described are pharmaceutical compositions and medicaments that include the Formula I compounds, as well as methods of using such estrogen receptor modulators, alone and in combination with other therapeutic agents, for treating diseases or conditions that are mediated or dependent upon estrogen receptors.Type: GrantFiled: April 17, 2018Date of Patent: April 6, 2021Assignee: Genentech, Inc.Inventors: Sharada Labadie, Jun Liang, Daniel Fred Ortwine, Xiaojing Wang, Jason Zbieg, Birong Zhang, Simon Charles Goodacre, Nicholas Charles Ray, Jun Li, Tommy Lai, Jiangpeng Liao, Zhiguo Liu, John Wai, Tao Wang
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Patent number: 10968203Abstract: Described herein are pyrimidinyl-pyridyloxy-naphthyl compounds with inositol requiring enzyme 1 (IRE1) modulation activity or function having the Formula I or I? structure: or stereoisomers, tautomers, or pharmaceutically acceptable salts thereof, and with the substituents and structural features described herein. Also described are pharmaceutical compositions and medicaments that include the Formula I or I? compounds, as well as methods of using such IRE1 modulators, alone and in combination with other therapeutic agents, for treating diseases or conditions that are mediated or dependent upon estrogen receptors.Type: GrantFiled: May 24, 2018Date of Patent: April 6, 2021Assignees: Genentech, Inc., The Regents of the University of CaliforniaInventors: Marie-Gabrielle Braun, Paul Gibbons, Wendy Lee, Cuong Ly, Joachim Rudolph, Jacob Schwarz, Avi Ashkenazi, Leo Fu, Tommy Lai, Fei Wang, Ramsay Beveridge, Liang Zhao
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Publication number: 20180265497Abstract: Described herein are pyrimidinyl-pyridyloxy-naphthyl compounds with inositol requiring enzyme 1 (IRE1) modulation activity or function having the Formula I or I? structure: or stereoisomers, tautomers, or pharmaceutically acceptable salts thereof, and with the substituents and structural features described herein. Also described are pharmaceutical compositions and medicaments that include the Formula I or I? compounds, as well as methods of using such IRE1 modulators, alone and in combination with other therapeutic agents, for treating diseases or conditions that are mediated or dependent upon estrogen receptors.Type: ApplicationFiled: May 24, 2018Publication date: September 20, 2018Applicants: Genentech, Inc., The Regents of the University of CaliforniaInventors: Marie-Gabrielle Braun, Paul Gibbons, Wendy Lee, Cuong Ly, Joachim Rudolph, Jacob Schwarz, Avi Ashkenazi, Leo Fu, Tommy Lai, Fei Wang, Ramsay Beveridge, Liang Zhao
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Publication number: 20180235945Abstract: Described herein are tetrahydro-pyrido[3,4-b]indol-1-yl compounds with estrogen receptor modulation activity or function having the Formula I structure: and stereoisomers, tautomers, or pharmaceutically acceptable salts thereof, and with the substituents and structural features described herein. Also described are pharmaceutical compositions and medicaments that include the Formula I compounds, as well as methods of using such estrogen receptor modulators, alone and in combination with other therapeutic agents, for treating diseases or conditions that are mediated or dependent upon estrogen receptors.Type: ApplicationFiled: April 17, 2018Publication date: August 23, 2018Applicant: Genentech, Inc.Inventors: SHARADA LABADIE, JUN LIANG, DANIEL FRED ORTWINE, XIAOJING WANG, JASON ZBIEG, BIRONG ZHANG, SIMON CHARLES GOODACRE, NICHOLAS CHARLES RAY, JUN LI, TOMMY LAI, JIANGPENG LIAO, ZHIGUO LIU, JOHN WAI, TAO WANG
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Patent number: 8236646Abstract: A method for manufacturing an integrated circuit structure includes providing a semiconductor substrate and forming two trenches in the semiconductor substrate to define an active region therebetween. An implanted source region is formed in one of the trenches on one side of the active region. An implanted drain region is formed in the other trench on the other side of the active region. Shallow trench isolations are then formed in the trenches. One or more gates are formed over the active region, and contacts to the implanted source region and the implanted drain region are formed.Type: GrantFiled: November 6, 2003Date of Patent: August 7, 2012Assignee: GLOBALFOUNDRIES Singapore Pte. Ltd.Inventors: Tze Ho Simon Chan, Weining Li, Elgin Quek, Jia Zhen Zheng, Pradeep Ramachandramurthy Yelehanka, Tommy Lai
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Patent number: 7501683Abstract: An integrated circuit structure includes providing a semiconductor substrate and forming at least one oxide-nitride-oxide dielectric layer above the semiconductor substrate. At least one implantation is formed into at least one area of the semiconductor substrate beneath the oxide-nitride-oxide dielectric layer subsequent to the formation of the oxide-nitride-oxide dielectric layer.Type: GrantFiled: May 30, 2006Date of Patent: March 10, 2009Assignee: Chartered Semiconductor Manufacturing Ltd.Inventors: Tommy Lai, Pradeep Ramachandramurthy Yelehanka, Jia Zhen Zheng, Weining Li
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Patent number: 7148522Abstract: An integrated circuit structure includes a semiconductor substrate and a thyristor formed thereon. The thyristor has at least four layers, with three P-N junctions therebetween. At least two of the layers are formed horizontally and at least two of the layers are formed vertically. A gate is formed adjacent at least one of the vertically formed layers. An access transistor is formed on the semiconductor substrate, and an interconnect is formed between the thyristor and the access transistor.Type: GrantFiled: December 11, 2004Date of Patent: December 12, 2006Assignee: Chartered Semiconductor Manufacturing Ltd.Inventors: Elgin Quek, Pradeep Ramachandramurthy Yelehanka, Jia Zhen Zheng, Tommy Lai, Weining Li
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Patent number: 7126197Abstract: A method of forming a power MOSFET having a substrate of a first conductivity type and a body region of a second conductivity type. The method includes the steps of forming a gate region of a pre-determined pattern and with a plurality of gate elements partially covering the substrate. The gate element has a stepped cross-sectional profile with a thicker portion and a thinner portion. The thicker portion is adapted to substantially prevent passage of impurities therethrough into the substrate during the impurities implantation step. The thinner portion is adapted to allow partial passage of impurities therethrough during the impurities implantation step. Impurities are implanted into the substrate from the gate region side of the substrate to form a body region of the second conductivity type.Type: GrantFiled: May 13, 2004Date of Patent: October 24, 2006Inventors: Kin On Johnny Sin, Mau Lam Tommy Lai
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Publication number: 20060220110Abstract: An integrated circuit structure includes providing a semiconductor substrate and forming at least one oxide-nitride-oxide dielectric layer above the semiconductor substrate. At least one implantation is formed into at least one area of the semiconductor substrate beneath the oxide-nitride-oxide dielectric layer subsequent to the formation of the oxide-nitride-oxide dielectric layer.Type: ApplicationFiled: May 30, 2006Publication date: October 5, 2006Applicant: CHARTERED SEMICONDUCTOR MANUFACTURING LTD.Inventors: Tommy Lai, Pradeep Yelehanka, Jia Zhen Zheng, Weining Li
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Patent number: 7067362Abstract: A method for manufacturing an integrated circuit structure includes providing a semiconductor substrate and forming at least one oxide-nitride-oxide dielectric layer above the semiconductor substrate. At least one implantation is formed into at least one area of the semiconductor substrate beneath the oxide-nitride-oxide dielectric layer subsequent to the formation of the oxide-nitride-oxide dielectric layer.Type: GrantFiled: October 17, 2003Date of Patent: June 27, 2006Assignee: Chartered Semiconductor Manufacturing Ltd.Inventors: Tommy Lai, Pradeep Ramachandramurthy Yelehanka, Jia Zhen Zheng, Weining Li
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Publication number: 20050101102Abstract: A method for manufacturing an integrated circuit structure includes providing a semiconductor substrate and forming two trenches in the semiconductor substrate to define an active region therebetween. An implanted source region is formed in one of the trenches on one side of the active region. An implanted drain region is formed in the other trench on the other side of the active region. Shallow trench isolations are then formed in the trenches. One or more gates are formed over the active region, and contacts to the implanted source region and the implanted drain region are formed.Type: ApplicationFiled: November 6, 2003Publication date: May 12, 2005Applicant: CHARTERED SEMICONDUCTOR MANUFACTURING LTD.Inventors: Tze Ho Chan, Weining Li, Elgin Quek, Jia Zheng, Pradeep Ramachandramurthy Yelehanka, Tommy Lai
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Publication number: 20050098794Abstract: An integrated circuit structure includes a semiconductor substrate and a thyristor formed thereon. The thyristor has at least four layers, with three P-N junctions therebetween. At least two of the layers are formed horizontally and at least two of the layers are formed vertically. A gate is formed adjacent at least one of the vertically formed layers. An access transistor is formed on the semiconductor substrate, and an interconnect is formed between the thyristor and the access transistor.Type: ApplicationFiled: December 11, 2004Publication date: May 12, 2005Applicant: CHARTERED SEMICONDUCTOR MANUFACTURING LTD.Inventors: Elgin Quek, Pradeep Ramachandramurthy Yelehanka, Jia Zheng, Tommy Lai, Weining Li
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Publication number: 20050085056Abstract: A method for manufacturing an integrated circuit structure includes providing a semiconductor substrate and forming at least one oxide-nitride-oxide dielectric layer above the semiconductor substrate. At least one implantation is formed into at least one area of the semiconductor substrate beneath the oxide-nitride-oxide dielectric layer subsequent to the formation of the oxide-nitride-oxide dielectric layer.Type: ApplicationFiled: October 17, 2003Publication date: April 21, 2005Applicant: CHARTERED SEMICONDUCTOR MANUFACTURING LTD.Inventors: Tommy Lai, Pradeep Ramachandramurthy Yelehanka, Jia Zheng, Weining Li
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Publication number: 20050073012Abstract: Current practice of the common source configuration is to connect the sources of the two discrete MOSFETs (housed either in separated packages or in a single package) externally on the printed circuit board. Because the gate pads and source pads of the two dies are alternatively placed between gate and source, it does not allow the sources of the power MOSFETs to be connected internally, which requires an additional layer of circuit board to connect the sources and the gates externally. This invention provides a novel electronic device layout design and a novel packaging technique for common source configuration, placing two MOSFETs in a package with their sources connected to a single source post which is located between tow gate posts. In order to facilitate gate bonding and to prevent any shorting between gate and source, two gate pads are used and placed at the upper adjacent corners of each MOSFET.Type: ApplicationFiled: March 17, 2003Publication date: April 7, 2005Applicant: Analog Power Intellectual Properties LimitedInventors: Johnny Sin, Ming Liu, Tommy Lai
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Publication number: 20050026337Abstract: A method for manufacturing an integrated circuit structure includes providing a semiconductor substrate and forming a thyristor thereon. The thyristor has at least four layers, with three P—N junctions therebetween. At least two of the layers are formed horizontally and at least two of the layers are formed vertically. A gate is formed adjacent at least one of the vertically formed layers. An access transistor is formed on the semiconductor substrate, and an interconnect is formed between the thyristor and the access transistor.Type: ApplicationFiled: July 28, 2003Publication date: February 3, 2005Applicant: CHARTERED SEMICONDUCTOR MANUFACTURING LTD.Inventors: Elgin Quek, Pradeep Ramachandramurthy Yelehanka, Jia Zheng, Tommy Lai, Weining Li
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Patent number: 6849481Abstract: A method for manufacturing an integrated circuit structure includes providing a semiconductor substrate and forming a thyristor thereon. The thyristor has at least four layers, with three P-N junctions therebetween. At least two of the layers are formed horizontally and at least two of the layers are formed vertically. A gate is formed adjacent at least one of the vertically formed layers. An access transistor is formed on the semiconductor substrate, and an interconnect is formed between the thyristor and the access transistor.Type: GrantFiled: July 28, 2003Date of Patent: February 1, 2005Assignee: Chartered Semiconductor Manufacturing Ltd.Inventors: Elgin Quek, Pradeep Ramachandramurthy Yelehanka, Jia Zhen Zheng, Tommy Lai, Weining Li