Patents by Inventor Tomoaki HAGA

Tomoaki HAGA has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Immunoglobulin binding protein, and affinity support using same
    Patent number: 11884705
    Abstract: Provided are a protein L-derived immunoglobulin binding protein having an increased antibody dissociation rate under acidic conditions, and an affinity support using the same. Disclosed are an immunoglobulin binding protein comprising at least one mutant of an immunoglobulin binding domain, and an affinity support comprising a solid-phase support having the immunoglobulin binding protein bound thereto. A mutant of the immunoglobulin binding domain consists of an amino acid sequence having an identity of at least 85% with the sequence set forth in any one of SEQ ID NO:1 to SEQ ID NO:9 and a predetermined mutation, and the mutant has immunoglobulin ? chain binding activity.
    Type: Grant
    Filed: September 25, 2018
    Date of Patent: January 30, 2024
    Assignees: JSR CORPORATION, JSR Life Sciences Corporation, JSR Life Sciences, LLC, JSR Micro N.V.
    Inventors: Jun-ichi Yasuoka, Kiichi Yoshimura, Tomoaki Haga
  • IMMUNOGLOBULIN-BINDING PROTEIN AND AFFINITY SUPPORT USING SAME
    Publication number: 20220242975
    Abstract: An affinity support having improved binding capacity for target proteins. An immunoglobulin-binding protein including a mutant immunoglobulin-binding domain, an affinity support including a solid-phase support and the immunoglobulin-binding protein immobilized thereto. The mutant immunoglobulin-binding domain consists of an amino acid sequence having at least 85% identity with an amino acid sequence of any of SEQ ID NOs: 1 to 12.
    Type: Application
    Filed: February 28, 2020
    Publication date: August 4, 2022
    Applicants: JSR CORPORATION, JSR LIFE SCIENCES, LLC, JSR MICRO N.V.
    Inventors: Toshinari HONDA, Satoshi NAKAMURA, Shunsuke ONOGI, Tomoaki HAGA
  • IMMUNOGLOBULIN-BINDING PROTEIN, AND AFFINITY CARRIER USING SAME
    Publication number: 20210179671
    Abstract: An affinity carrier may have improved alkali resistance. An immunoglobulin-binding protein containing a mutant polypeptide chain, as well as an affinity carrier containing a solid-phase carrier to which the immunoglobulin-binding protein is bound, may be a mutant polypeptide chain having an amino acid sequence having at least 85% identity to an amino acid sequence indicated by any of SEQ ID NO: 1-6 and 57-62, having a predetermined mutation, and having immunoglobulin-binding activity.
    Type: Application
    Filed: August 23, 2019
    Publication date: June 17, 2021
    Applicants: JSR CORPORATION, JSR MICRO INC., JSR MICRO N.V.
    Inventors: Tomoaki HAGA, Takashi ICHII, Shunsuke ONOGI, Satoshi NAKAMURA, Toshinari HONDA, Tomoyuki KAMIDE
  • IMMUNOGLOBULIN BINDING PROTEIN, AND AFFINITY SUPPORT USING SAME
    Publication number: 20200262873
    Abstract: Provided are a protein L-derived immunoglobulin binding protein having an increased antibody dissociation rate under acidic conditions, and an affinity support using the same. Disclosed are an immunoglobulin binding protein comprising at least one mutant of an immunoglobulin binding domain, and an affinity support comprising a solid-phase support having the immunoglobulin binding protein bound thereto. A mutant of the immunoglobulin binding domain consists of an amino acid sequence having an identity of at least 85% with the sequence set forth in any one of SEQ ID NO:1 to SEQ ID NO:9 and a predetermined mutation, and the mutant has immunoglobulin ? chain binding activity.
    Type: Application
    Filed: September 25, 2018
    Publication date: August 20, 2020
    Applicants: JSR CORPORATION, JSR Life Sciences Corporation, JSR Micro Inc., JSR Micro N.V.
    Inventors: Jun-ichi YASUOKA, Kiichi YOSHIMURA, Tomoaki HAGA