Abstract: Head-up display includes: display element for displaying an image, and a projection optical system for projecting the image, which is displayed on display element, onto viewing region of viewer. The projection optical system includes combiner that is disposed at a position in an optical path from display element to viewing region of viewer. Combiner has a surface at which light incident from display element enters; the surface has a curved surface shape. Combiner has an effective region corresponding to viewing region of viewer. In the effective region, combiner has a horizontal cross-sectional shape that changes in thickness along from the center toward an end.

Abstract: Head-up display includes: display element for displaying an image, and a projection optical system for projecting the image, which is displayed on display element, onto viewing region of viewer. The projection optical system includes combiner that is disposed at a position in an optical path from display element to viewing region of viewer. Combiner has a surface at which light incident from display element enters; the surface has a curved surface shape. Combiner has an effective region corresponding to viewing region of viewer. In the effective region, combiner has a horizontal cross-sectional shape that changes in thickness along from the center toward an end.

Abstract: A virtual image display device includes: a projection member that projects an image; and a projection optical system that forms a virtual image. A virtual image distance from an observer to the virtual image is not less than 2,500 mm. The projection optical system has one or more reflectors. A reflection surface of a final reflector that is included in one or more reflectors and finally reflects a light ray satisfies the following Conditional Relation 1: 10°?|?z max??z min|?30°??Conditional Relation 1 where ?z is an angle between a normal vector perpendicular to a tangent plane passing through an origin of the final reflector and a normal vector with respect to a tangent plane at any given point on the final reflector, ?z max is a maximum value of ?z, and ?z min is a minimum value of ?z. This arrangement provides a small-size virtual image display device.

Abstract: This disclosure relates to new assay methods for analysis of RNA, e.g., from circulating tumor cells (CTCs), tumor-specific exosomes, or tumor-specific cell-free RNA, in a subject's blood sample to determine an expression level of one or more lineage markers in the blood sample, wherein the expression level of a specific one or more lineage markers is predictive of progression-free survival and overall survival for a specific anti-cancer treatment regimen in that subject.

Abstract: Provided is a head-up display which projects an image on a windshield and forms a virtual image visually recognizable by a viewer. The head-up display includes a display element which displays the image and a projection optical system which guides the image displayed by the display element to the windshield and forms the virtual image. The projection optical system includes at least two mirrors each having a reflective surface with a concave profile. The windshield has a curvature radius Rx in the right-left direction of the windshield which satisfies 0.05<EBx/Rxmax<0.50, where EBx denotes an eye box size in an X direction in which the virtual image is visually recognizable by the viewer, and Rxmax denotes a maximum value of Rx in an effective ray area of the windshield.

Abstract: A virtual image display device includes: a projection member that projects an image; and a projection optical system that forms a virtual image. A virtual image distance from an observer to the virtual image is not less than 2,500 mm. The projection optical system has one or more reflectors. A reflection surface of a final reflector that is included in one or more reflectors and finally reflects a light ray satisfies the following Conditional Relation 1: 10°?|?z max??z min|?30°??Conditional Relation 1 where ?z is an angle between a normal vector perpendicular to a tangent plane passing through an origin of the final reflector and a normal vector with respect to a tangent plane at any given point on the final reflector, ?z max is a maximum value of ?z, and ?z min is a minimum value of ?z. This arrangement provides a small-size virtual image display device.

Abstract: A rubber composition of the present technology contains, per 100 parts by mass of a diene polymer that can be vulcanized by sulfur, from 0.5 parts by mass to 4 parts by mass of sulfur, and from 0.004 mol to 0.17 mol of a polyhydric alcohol compound having a molecular weight of 300 or less.

Abstract: The present technology provides a rubber composition comprising: from 1.0 part by mass to 15 parts by mass of water, and from 0.5 parts by mass to 10 parts by mass of water absorbing resin as a water retaining agent, or from 0.5 parts by mass to 20 parts by mass of inorganic water retaining agent as a water retaining agent, per 100 parts by mass of diene polymer that can be sulfur-vulcanized.

Abstract: Head-up display includes: display element for displaying an image, and a projection optical system for projecting the image, which is displayed on display element, onto viewing region of viewer. The projection optical system includes combiner that is disposed at a position in an optical path from display element to viewing region of viewer. Combiner has a surface at which light incident from display element enters; the surface has a curved surface shape. Combiner has an effective region corresponding to viewing region of viewer. In the effective region, combiner has a horizontal cross-sectional shape that changes in thickness along from the center toward an end.

Abstract: A rubber composition of the present technology contains: 100 parts by mass of diene polymer that can be vulcanized by sulfur, from 0.5 parts by mass to 5 parts by mass of sulfur, and from 0.8 parts by mass to 17 parts by mass of hydroxy group-containing compound having a molecular weight of 200 or less.

Abstract: A rubber composition of the present technology comprises: from 0.5 parts by mass to 1.5 parts by mass of sulfur, from 0.2 parts by mass to 0.6 parts by mass of a thiuram vulcanization accelerator, from 0.2 parts by mass to 0.6 parts by mass of a guanidine vulcanization accelerator, from 0.15 parts by mass to 0.8 parts by mass of a sulfenamide vulcanization accelerator, and from 0.1 parts by mass to 1.5 parts by mass of a thiourea vulcanization accelerator per 100 parts by mass of a diene polymer containing a chloroprene rubber.

Abstract: This disclosure relates to new assay methods for analysis of circulating tumor cells (CTCs) in blood samples for detection, e.g., early detection, and/or monitoring of disease, e.g., cancer. The methods provide ultra-high sensitivity and specificity, and include the use of microfluidic isolation of CTCs and digital detection of RNA derived from the CTCs.

Abstract: A rubber composition of the present technology comprises: from 0.5 parts by mass to 1.5 parts by mass of sulfur, from 0.2 parts by mass to 0.6 parts by mass of a thiuram vulcanization accelerator, from 0.2 parts by mass to 0.6 parts by mass of a guanidine vulcanization accelerator, from 0.15 parts by mass to 0.8 parts by mass of a sulfenamide vulcanization accelerator, and from 0.1 parts by mass to 1.5 parts by mass of a thiourea vulcanization accelerator per 100 parts by mass of a diene polymer containing a chloroprene rubber.

Abstract: A rubber composition of the present technology comprises: from 0.5 parts by mass to 1.5 parts by mass of sulfur, from 0.2 parts by mass to 0.6 parts by mass of a thiuram vulcanization accelerator, from 0.2 parts by mass to 0.6 parts by mass of a guanidine vulcanization accelerator, from 0.15 parts by mass to 0.8 parts by mass of a sulfenamide vulcanization accelerator, and from 0.1 parts by mass to 1.5 parts by mass of a thiourea vulcanization accelerator per 100 parts by mass of a diene polymer containing a chloroprene rubber.

Abstract: An antibody against mutant ?-actinin-4 having an amino acid sequence with at least one amino acid residue substitution in the region between position 245 and 263 in the amino acid sequence of ?-actinin-4, wherein the antibody recognizes all or a part of the substituted amino acid residue(s) in the region.

Abstract: An ocular optical system comprising at least five lens elements, and including, in order from a display surface side to an exit side, a first lens unit having negative optical power, a second lens unit having positive optical power, and a third lens unit having positive optical power, wherein the second lens unit moves along an optical axis for adjustment of diopter scale, and a finder optical system comprising a display device having a display surface on which an image is displayed, and the above-mentioned ocular optical system.

Abstract: A rubber composition of the present technology comprises: from 0.5 parts by mass to 1.5 parts by mass of sulfur, from 0.2 parts by mass to 0.6 parts by mass of a thiuram vulcanization accelerator, from 0.2 parts by mass to 0.6 parts by mass of a guanidine vulcanization accelerator, from 0.15 parts by mass to 0.8 parts by mass of a sulfenamide vulcanization accelerator, and from 0.1 parts by mass to 1.5 parts by mass of a thiourea vulcanization accelerator per 100 parts by mass of a diene polymer containing a chloroprene rubber.

Abstract: The present technology provides a rubber composition comprising: from 1.0 part by mass to 15 parts by mass of water, and from 0.5 parts by mass to 10 parts by mass of water absorbing resin as a water retaining agent, or from 0.5 parts by mass to 20 parts by mass of inorganic water retaining agent as a water retaining agent, per 100 parts by mass of diene polymer that can be sulfur-vulcanized.

Abstract: An ocular optical system comprising at least five lens elements, and including, in order from a display surface side to an exit side, a first lens unit having negative optical power, a second lens unit having positive optical power, and a third lens unit having positive optical power, wherein the second lens unit moves along an optical axis for adjustment of diopter scale, and a finder optical system comprising a display device having a display surface on which an image is displayed, and the above-mentioned ocular optical system.

Abstract: To provide a rubber composition having excellent durability against external environment, and a vulcanization rubber product and a hose using the same. The rubber composition of the present technology is a rubber composition comprising: a rubber component (A), a water repellent (B), and hydrotalcite (C). In the rubber composition, the rubber component (A) comprises CR, SBR, or both CR and SBR; and the water repellent (B) comprises one or more types of ultra high molecular weight polyethylene powders or fatty acid amide compounds. The total content of the components of the water repellent (B) is from 2 parts by mass to 30 parts by mass per 100 parts by mass of the rubber component (A); and the content of the hydrotalcite (C) is from 2 parts by mass to 20 parts by mass per 100 parts by mass of the rubber component (A).