Patents by Inventor Tomofumi Setsuta

Tomofumi Setsuta has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • TRIAZINE COMPOUND SALT, CRYSTAL FORM THEREOF, AND PRODUCTION METHOD THEREFOR
    Publication number: 20230365513
    Abstract: The present invention provides a salt of a triazine compound which has an inhibitory action against aldosterone synthase and is useful as a drug, and especially as a drug for preventing or treating primary aldosteronism and the like, a crystal thereof, and a method for producing the same. Specifically, the present invention provides a pharmaceutically acceptable salt of 3-[4-[[trans-4-(acetamino)cyclohexyl]carbamoylmethyl]piperazin-1-yl]-5-(p-tolyl)-1,2,4-triazine, wherein the salt is hydrobromide, sulfate, succinate, or tosilate, and the like.
    Type: Application
    Filed: September 15, 2021
    Publication date: November 16, 2023
    Applicant: MITSUBISHI TANABE PHARMA CORPORATION
    Inventors: Takafumi YAMAGAMI, Tomofumi SETSUTA, Yoshihiro SUGIURA, Naoko UEDA
  • Method for producing triazine compound
    Patent number: 11339135
    Abstract: The present invention provides an industrially advantageous method for producing a 3,5-disubstituted triazine compound that is useful as an active pharmaceutical ingredient. More specifically, the present invention provides a production method, whereby it becomes possible to efficiently produce a 3-oxo-5-substituted triazine in water without the need to isolate an intermediate that may have mutagenicity, and it also becomes possible to perform the production without the need to isolate a product in each of multiple steps. Namely, the present invention provides a method for producing a compound represented by formula I or a salt thereof, the method including a step of reacting a compound represented by the following formula IV or a salt thereof with a base in water, and optionally including a step of forming a salt thereof.
    Type: Grant
    Filed: November 29, 2017
    Date of Patent: May 24, 2022
    Assignee: MITSUBISHI TANABE PHARMA CORPORATION
    Inventors: Takafumi Yamagami, Souta Yamasaki, Tomofumi Setsuta, Ryo Sakakibara, Yosuke Matsumura
  • METHOD FOR PRODUCING TRIAZINE COMPOUND
    Publication number: 20210380541
    Abstract: The present invention provides an industrially advantageous method for producing a 3,5-disubstituted triazine compound that is useful as an active pharmaceutical ingredient. More specifically, the present invention provides a production method, whereby it becomes possible to efficiently produce a 3-oxo-5-substituted triazine in water without the need to isolate an intermediate that may have mutagenicity, and it also becomes possible to perform the production without the need to isolate a product in each of multiple steps. Namely, the present invention provides a method for producing a compound represented by formula I or a salt thereof, the method including a step of reacting a compound represented by the following formula IV or a salt thereof with a base in water, and optionally including a step of forming a salt thereof.
    Type: Application
    Filed: November 29, 2017
    Publication date: December 9, 2021
    Applicant: MITSUBISHI TANABE PHARMA CORPORATION
    Inventors: Takafumi YAMAGAMI, Souta YAMASAKI, Tomofumi SETSUTA, Ryo SAKAKIBARA, Yosuke MATSUMURA
  • Homocysteine synthase inhibitor
    Patent number: 8513235
    Abstract: The invention provides a homocysteine synthase inhibitor useful for the prophylaxis or treatment of diseases involving homocysteine synthase. The homocysteine synthase inhibitor is a compound of the formula (I) wherein each symbol is as defined herein, or a pharmacologically acceptable salt thereof, or a solvate thereof.
    Type: Grant
    Filed: April 10, 2009
    Date of Patent: August 20, 2013
    Assignee: Mitsubishi Tanabe Pharma Corporation
    Inventors: Akira Nakao, Hiroko Suzuki, Ryo Tatsumi, Maki Seki, Minoru Tanaka, Tomofumi Setsuta, Hiroshi Iwasaki
  • THERAPEUTIC AGENT FOR CEREBRAL INFARCTION
    Publication number: 20120196824
    Abstract: The invention provides a therapeutic drug for ischemic stroke. The therapeutic drug has the formula (I) wherein each symbol is as defined herein, or a pharmacologically acceptable salt thereof, or a solvate thereof, as an active ingredient.
    Type: Application
    Filed: October 8, 2010
    Publication date: August 2, 2012
    Applicant: MITSUBISHI TANABE PHARMA CORPORATION
    Inventors: Akira Nakao, Hiroko Suzuki, Ryo Tatsumi, Tomofumi Setsuta, Maki Seki, Hiroshi Iwasaki, Minoru Tanaka
  • HOMOCYSTEINE SYNTHASE INHIBITOR
    Publication number: 20110034440
    Abstract: The invention provides a homocysteine synthase inhibitor useful for the prophylaxis or treatment of diseases involving homocysteine synthase. The homocysteine synthase inhibitor is a compound of the formula (I) wherein each symbol is as defined herein, or a pharmacologically acceptable salt thereof, or a solvate thereof.
    Type: Application
    Filed: April 10, 2009
    Publication date: February 10, 2011
    Applicant: MITSUBISHI TANABE PHARMA CORPORATION
    Inventors: Akira Nakao, Hiroko Suzuki, Ryo Tatsumi, Maki Seki, Minoru Tanaka, Tomofumi Setsuta, Hiroshi Iwasaki