Patents by Inventor Tomohide Tsukahara

Tomohide Tsukahara has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • CANCER-STEM-CELL-SPECIFIC ANTIBODY
    Publication number: 20220033513
    Abstract: The present invention pertains to: an antibody that specifically recognizes cancer stem cells; a pharmaceutical composition containing the antibody, in particular a pharmaceutical composition for treating cancer; the utilization of these; a method for treating cancer, the method targeting cancer stem cells; etc. The above problem was solved by providing an antibody that recognizes a complex of a cancer stem cell antigen peptide and an MHC, and a pharmaceutical composition containing the antibody as an active component.
    Type: Application
    Filed: October 4, 2019
    Publication date: February 3, 2022
    Applicant: Sapporo Medical University
    Inventors: Tomohide Tsukahara, Toshihiko Torigoe
  • Tumor antigen peptide and use thereof
    Patent number: 9260499
    Abstract: Disclosed is a peptide consisting of the identical amino acid sequence or a substantially identical amino acid sequence to the amino acid sequence depicted in SEQ ID NO:4, wherein the peptide binds to an HLA antigen and is recognized by cytotoxic T cells. The peptide of the present invention can be used in vivo or in vitro as an agent for inducing CTL, that is, cancer vaccine, and exerts therapeutic or ameliorating effects on tumors such as osteosarcoma, renal cancer, and others. The peptide of the present invention is also useful as a tumor marker directed to tumors such as sarcoma, renal cancer, and others.
    Type: Grant
    Filed: October 19, 2009
    Date of Patent: February 16, 2016
    Assignees: SAPPORO MEDICAL UNIVERSITY, SUMITOMO DAINTPPON PHARMA CO., LTD.
    Inventors: Noriyuki Sato, Tomohide Tsukahara, Satoshi Kawaguchi, Takuro Wada
  • TUMOR ANTIGEN PEPTIDE AND USE THEREOF
    Publication number: 20110200629
    Abstract: Disclosed is a peptide consisting of the identical amino acid sequence or a substantially identical amino acid sequence to the amino acid sequence depicted in SEQ ID NO:4, wherein the peptide binds to an HLA antigen and is recognized by cytotoxic T cells. The peptide of the present invention can be used in vivo or in vitro as an agent for inducing CTL, that is, cancer vaccine, and exerts therapeutic or ameliorating effects on tumors such as osteosarcoma, renal cancer, and others. The peptide of the present invention is also useful as a tumor marker directed to tumors such as sarcoma, renal cancer, and others.
    Type: Application
    Filed: October 19, 2009
    Publication date: August 18, 2011
    Applicants: DAINIPPON SUMITOMO PHARMA CO., LTD.
    Inventors: Noriyuki Sato, Tomohide Tsukahara, Satoshi Kawaguchi, Takuro Wada
  • TUMOR ANTIGEN PROTEIN AND USE THEREOF
    Publication number: 20100255579
    Abstract: An inducer of cytotoxic T cells comprising as an active ingredient a protein which comprises the same or substantially the same amino acid sequence as that shown in SEQ ID NO: 2, or a peptide derived from the protein above is provided.
    Type: Application
    Filed: February 8, 2010
    Publication date: October 7, 2010
    Applicants: Dainippon Sumitomo Pharma Co., Ltd., Noriyuki SATO
    Inventors: Noriyuki SATO, Tomohide Tsukahara, Yuki Nabeta, Satoshi Kawaguchi, Hideyuki Ikeda, Takuro Wada, Toshihiko Yamashita
  • Tumor antigen protein and use thereof
    Patent number: 7700108
    Abstract: An inducer of cytotoxic T cells comprising as an active ingredient a protein which comprises the same or substantially the same amino acid sequence as that shown in SEQ ID NO: 2, or a peptide derived from the protein above is provided.
    Type: Grant
    Filed: September 19, 2003
    Date of Patent: April 20, 2010
    Assignees: Dainippon Sumitomo Pharma Co., Ltd.
    Inventors: Noriyuki Sato, Tomohide Tsukahara, Yuki Nabeta, Satoshi Kawaguchi, Hideyuki Ikeda, Takuro Wada, Toshihiko Yamashita
  • Tumor Antigen Protein and Use Thereof
    Publication number: 20080014636
    Abstract: An inducer of cytotoxic T cells comprising as an active ingredient a protein which comprises the same or substantially the same amino acid sequence as that shown in SEQ ID NO: 2, or a peptide derived from the protein above is provided.
    Type: Application
    Filed: September 19, 2003
    Publication date: January 17, 2008
    Inventors: Noriyuki Sato, Tomohide Tsukahara, Yuki Nabeta, Satoshi Kawaguchi, Hideyuki Ikeda, Takuro Wada, Toshihiko Yamashita