Patents by Inventor Tomohiko Akahoshi

Tomohiko Akahoshi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11484258
    Abstract: A method for obtaining an index for non-invasively identifying NASH is provided. A NASH determination method comprising a method for acquiring free radical consumption speed information by non-invasively detecting a redox reaction in a liver of a test animal in real time, comprises a step (1) of obtaining free radical concentration data by applying a magnetic resonance method to the liver as a measurement target after administering a probe into a body; a step (2) of obtaining imaging information by processing the obtained free radical concentration data; and a step (3) of obtaining a free radical consumption speed by kinetically measuring the imaging information over time, and comprises a step of determining whether or not the test animal has NASH, based on the free radical consumption speed information obtained through application to the test animal.
    Type: Grant
    Filed: June 9, 2017
    Date of Patent: November 1, 2022
    Assignee: KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION
    Inventors: Masaharu Murata, Fuminori Hyodo, Makoto Hashizume, Ryosuke Nakata, Tomohiko Akahoshi
  • Publication number: 20190133517
    Abstract: A method for obtaining an index for non-invasively identifying NASH is provided. A NASH determination method comprising a method for acquiring free radical consumption speed information by non-invasively detecting a redox reaction in a liver of a test animal in real time, comprises a step (1) of obtaining free radical concentration data by applying a magnetic resonance method to the liver as a measurement target after administering a probe into a body; a step (2) of obtaining imaging information by processing the obtained free radical concentration data; and a step (3) of obtaining a free radical consumption speed by kinetically measuring the imaging information over time, and comprises a step of determining whether or not the test animal has NASH, based on the free radical consumption speed information obtained through application to the test animal.
    Type: Application
    Filed: June 9, 2017
    Publication date: May 9, 2019
    Applicant: KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION
    Inventors: Masaharu Murata, Fuminori Hyodo, Makoto Hashizume, Ryosuke Nakata, Tomohiko Akahoshi
  • Patent number: 10004532
    Abstract: A puncture assistance system provides information on a collapse state of a blood vessel to be punctured, caused by pressing action of an ultrasonic probe, when ultrasonic images of the blood vessel are acquired. A puncture assistance system 10 includes: vascular diameter detecting means 18 for detecting a vascular diameter during acquisition of the ultrasonic images from an ultrasonic diagnostic device 11; puncture assistance information generating means 12 for generating puncture assistance information for determination of whether or not puncture is allowed to be performed based on a collapse state of a blood vessel B caused by pressing action of an ultrasonic probe 15 against skin S by comparing a current vascular diameter detected by the vascular diameter detecting means 18 with a standard vascular diameter stored in advance; and a monitor 19 that presents the puncture assistance information.
    Type: Grant
    Filed: January 4, 2016
    Date of Patent: June 26, 2018
    Assignees: WASEDA UNIVERSITY, KIKUCHI SEISAKUSHO CO., LTD., KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION
    Inventors: Masakatsu Fujie, Yo Kobayashi, Mariko Tsukune, Ken Ichiryu, Nobuhiro Ogasawara, Bo Zhang, Makoto Hashizume, Tetsuo Ikeda, Tomohiko Akahoshi, Ryu Nakadate
  • Publication number: 20180000511
    Abstract: A puncture assistance system provides information on a collapse state of a blood vessel to be punctured, caused by pressing action of an ultrasonic probe, when ultrasonic images of the blood vessel are acquired. A puncture assistance system 10 includes: vascular diameter detecting means 18 for detecting a vascular diameter during acquisition of the ultrasonic images from an ultrasonic diagnostic device 11; puncture assistance information generating means 12 for generating puncture assistance information for determination of whether or not puncture is allowed to be performed based on a collapse state of a blood vessel B caused by pressing action of an ultrasonic probe 15 against skin S by comparing a current vascular diameter detected by the vascular diameter detecting means 18 with a standard vascular diameter stored in advance; and a monitor 19 that presents the puncture assistance information.
    Type: Application
    Filed: January 4, 2016
    Publication date: January 4, 2018
    Applicants: WASEDA UNIVERSITY, KIKUCHI SEISAKUSHO CO., LTD., KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION
    Inventors: Masakatsu Fujie, Yo Kobayashi, Mariko Tsukune, Ken Ichiryu, Nobuhiro Ogasawara, Bo Zhang, Makoto Hashizume, Tetsuo Ikeda, Tomohiko Akahoshi, Ryu Nakadate
  • Publication number: 20140010424
    Abstract: A diagnostic system comprises: a spectral imaging means that captures a spectral image within a predetermined wavelength range in a body cavity and obtains spectral image data; an image processing means that receives the spectral image data, determines an index value indicating a region that is highly likely to be a lesion from the spectral image data, and generates and outputs an extracted lesion image based on the index value; and a monitor on which the extracted lesion image is displayed. The image processing means performs multiple regression analysis for each pixel of the spectral image with the spectral image data as a dependent variable and respective light absorption properties of oxyhemoglobin and deoxyhemoglobin as independent variables, and determines the index value based on respective concentrations of the oxyhemoglobin and the deoxyhemoglobin.
    Type: Application
    Filed: February 10, 2012
    Publication date: January 9, 2014
    Applicants: KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION, HOYA CORPORATION
    Inventors: Toru Chiba, Makoto Hashizume, Takayuki Matsumoto, Kozo Konishi, Morimasa Tomikawa, Masaharu Murata, Tomohiko Akahoshi