Abstract: A cold storage heat exchanger includes a plurality of tubes, a coolant flowing in the tubes, a cold storage material container joined to the tubes, the cold storage material container defining a room that houses a cold storage material, and a distribution tank unit that distributes the coolant to the tubes. A coolant passage is formed in the tubes and the distribution tank unit. The distribution tank unit includes an aperture plate that reduces a passage cross-sectional area of the coolant passage. Among the plurality of tubes, the cold storage material container is joined to at least a tube disposed upstream in a coolant flow direction from the aperture plate in the coolant passage. Accordingly, cold storage performance may be improved.

Abstract: A biological information acquisition method for acquiring information on a living body on a basis of a quantified value of a physiologically active substance originated from the living body, includes a step of collecting the physiologically active substance from a body surface of the living body.

Abstract: A low temperature liquid tank includes: a storage tank having a bottom portion obtained by joining a plurality of bottom plates; and a support portion supporting the bottom portion. The support portion includes: an outer support portion supporting a margin of the storage tank; and an inner support portion disposed inside the outer support portion and having a heat insulation in which creep occurs when a load is applied. An initial height of an upper surface of the inner support portion is set so that, during a service life of the low temperature liquid tank, maximum bending stress applied to the bottom plates due to a difference between a height of the upper surface of the inner support portion and a height of an upper surface of the outer support portion remains equal to or smaller than an allowable bending stress of the bottom plates.

Abstract: A biological information acquisition method for acquiring information on a living body on a basis of a quantified value of a physiologically active substance originated from the living body, includes a step of collecting the physiologically active substance from a body surface of the living body.

Abstract: There is provided a base sequence analysis method including a nucleic acid amplification procedure of obtaining an amplification product by a nucleic acid amplification reaction, a turbidity measurement procedure of measuring turbidity of a reaction solution of the nucleic acid amplification reaction, and a melting curve analysis procedure of performing melting curve analysis of a probe nucleic acid chain and the amplification product at a reaction site of the nucleic acid amplification reaction.

Abstract: A biological information acquisition method for acquiring information on a living body on a basis of a quantified value of a physiologically active substance originated from the living body, includes a step of collecting the physiologically active substance from a body surface of the living body.

Abstract: There is provided a base sequence analysis method including a nucleic acid amplification procedure of obtaining an amplification product by a nucleic acid amplification reaction, a turbidity measurement procedure of measuring turbidity of a reaction solution of the nucleic acid amplification reaction, and a melting curve analysis procedure of performing melting curve analysis of a probe nucleic acid chain and the amplification product at a reaction site of the nucleic acid amplification reaction.

Abstract: There is provided a method for preparing a sample for a nucleic acid amplification reaction, the method including a heating step of applying heat to a nucleic acid-containing sample, and an electrodialysis step of bringing an electrical conductivity of the sample to 2,000 ?S/cm or less.

Abstract: Multiple cooling-storage containers are arranged in respective spaces formed between neighboring refrigerant tubes. The cooling-storage container is made of a pair of outer envelope portions, each forming a side wall. Multiple convex portions and concave portions are formed in the side walls so that air passages are formed between refrigerant tubes and the concave portions. A sectional area of the air passage formed in a lower portion of the cooling-storage container below a predetermined height is made larger than that of the air passage formed in an upper portion of the cooling-storage container above the predetermined height.

Abstract: In an evaporator unit, a first evaporator is coupled to an ejector to evaporate refrigerant flowing out of the ejector, a second evaporator is coupled to a refrigerant suction port of the ejector to evaporate the refrigerant to be drawn into the refrigerant suction port, a flow amount distributor is located to adjust a flow amount of the refrigerant distributed to the nozzle portion and a flow amount of the refrigerant distributed to the second evaporator, and a throttle mechanism is provided between the flow amount distributor and the second evaporator to decompress the refrigerant flowing into the second evaporator. The flow amount distributor is adapted as a gas-liquid separation portion and as a refrigerant distribution portion for distributing separated refrigerant into the nozzle portion and the second evaporator. Furthermore, the flow amount distributor and the ejector are arranged in line in a longitudinal direction of the ejector.

Abstract: Provided is a method of preparing a sample for nucleic acid amplification reaction, including: a procedure of dissolving a solid phase reagent at least containing DNA polymerase, cyclodextrin, and a binder, in a liquid containing a nucleic acid.

Abstract: An apparatus for preparing nucleic acids is provided which includes an anode, a cathode, and a space formed between the anode and the cathode. In addition, in the apparatus described above, the space includes a first porous film provided at an anode side, a second porous film provided at a cathode side, an inlet port which is proved in a region sandwiched between the first porous film and the second porous film and which introduces a specimen containing proteins and nucleic acids into the region, and a gel filter provided between the inlet port and the first porous film.

Abstract: A refrigerating cycle unit includes an ejector and a heat exchanger defined by layering a plurality of plates. Each of the plates has a refrigerant passage, and the refrigerant passages are connected by a header tank in a layering direction of the plates. At least two of the plates are fix plates having a fix portion to fix the ejector, and a communication portion through which the ejector and the header tank communicate with each other. The ejector is arranged between the fix portions of the fix plates in the layering direction, so as to be integrated with the heat exchanger.

Abstract: [Object] To provide a method of purifying nucleic acids where the operation is simple and the nucleic acids can be extracted in a short time with high efficiency. [Solving Means] A method of purifying nucleic acids including the step of adsorbing substances in a sample containing nucleic acids with an ion exchange resin 10 including a positive ion exchange resin and a negative ion exchange resin. As the positive ion exchange resin, a first positive ion exchange resin and a second positive ion exchange resin having an exclusion limit molecular weight lower than that of the first positive ion exchange resin may be used.

Abstract: There is provided a sample liquid injection tool including a reservoir section configured to store a sample liquid, a channel having one end protruding from an outer surface and configured to discharge the sample liquid therein from a protrusion end to an outside, and a heating unit and a filter installed between the reservoir section and the channel to enable passage of the liquid.

Abstract: There is provided a base sequence analysis method including a nucleic acid amplification procedure of obtaining an amplification product by a nucleic acid amplification reaction, a turbidity measurement procedure of measuring turbidity of a reaction solution of the nucleic acid amplification reaction, and a melting curve analysis procedure of performing melting curve analysis of a probe nucleic acid chain and the amplification product at a reaction site of the nucleic acid amplification reaction.

Abstract: A heat exchanger includes a heat exchanging section for performing heat exchange between a refrigerant and a cooling medium and a passage section. The passage section includes a first passage and a second passage for supplying the refrigerant to the heat exchanging section and a supply passage for supplying the refrigerant to the first passage and the second passage. The first passage and the second passage define a first opening portion and a second opening portion opening at an end of the supply passage. A minimum distance between an opening edge of the first opening portion and an inner surface of the supply passage is equal to a minimum distance between an opening edge of the second opening portion and the inner surface of the supply passage.

Abstract: There is provided a microchip for a nucleic acid amplification reaction including a reagent accommodation region including a solid-phase reagent and a particle, the solid-phase reagent containing a substance necessary for a nucleic acid amplification reaction.

Abstract: [Object] To provide a method for electrophoresing nucleic acids, which enables highly efficiently concentrating and purifying nucleic acids quickly by simple operation. [Solving Means] A method of electrophoresis includes electrophoresing a nucleic acid in which an intercalator having an anionic functional group has been inserted. The method includes mixing a sample containing a nucleic acid, a compound having a functional group which undergoes dehydration condensation reaction with carboxyl groups included in substances contained in the sample and a condensing agent of dehydration condensation reaction; and electrophoresing the nucleic acid. The method of concentrating and recovering nucleic acids, by increasing the negative charge of the nucleic acid bound with the intercalator, can increase electrophoretic velocity of nucleic acids.

Abstract: A nucleic acid quantification method that uses a microchip for nucleic acid amplification reaction, the microchip including an inlet through which a liquid is introduced from outside, a plurality of reaction regions provided as reaction sites of a nucleic acid amplification reaction, and a channel through which the liquid introduced through the inlet is supplied into each of the reaction regions, wherein the likelihood of the nucleic acid amplification reaction varies between the reaction regions, includes: flowing a detection target nucleic acid chain-containing solution through the channel and introducing the solution into each of the reaction regions to perform a nucleic acid amplification reaction; and detecting an amplification product in each of the reaction regions to specify the reaction regions in which the nucleic acid amplification reaction occurred.