Patents by Inventor Tomohiro Ookubo
Tomohiro Ookubo has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 9739477Abstract: There is provided a drain recovery system with which power for driving a feedwater pump can be reduced and the feedwater pump can be driven at low costs. The drain recovery system includes: a buffer tank; an assist tank disposed below the buffer tank; a first drain supply line that connects a load device and the buffer tank; a second drain supply line that connects the buffer tank and the assist tank; a drain supply valve; a communication line that establishes communication between the assist tank and the buffer tank; a communication valve; a steam supply line that supplies steam from a boiler to the assist tank; a steam supply valve; a feedwater line that supplies drain from the assist tank to the boiler; and a feedwater pump.Type: GrantFiled: April 27, 2012Date of Patent: August 22, 2017Assignee: MIURA CO., LTD.Inventors: Sohei Akinaga, Hiroyuki Hatanaka, Koji Nagai, Tomohiro Ookubo, Tetsuji Namato
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Patent number: 9540338Abstract: A cinnamic acid amide derivative having an excellent analgesic action is disclosed herein. The cinnamic acid amide derivative shows excellent analgesic actions to not only a nociceptive pain model animal, but also a neuropathic pain model animal, which is very useful as an agent for treating various pain diseases showing acute or chronic pains or neuropathic pains. The cinnamic acid amide derivative may be a compound represented by formula (I).Type: GrantFiled: December 27, 2013Date of Patent: January 10, 2017Assignee: NIPPON ZOKI PHARMACEUTICAL CO., LTD.Inventors: Tomohiro Ookubo, Ko Nakamura, Yoshitaka Nakazawa, Hiroyoshi Nanba, Hiroyuki Yoshida
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Patent number: 9500360Abstract: To achieve a downsized drain tank without reducing an effective drain recovery rate. A closed drain recovery system includes: a steam boiler (2); a closed-type drain tank (4); an air-open-type makeup water tank (7); a steam introduction line (10) for introducing a first flush steam within the drain tank (4) to the makeup water tank (7); a surplus drain introduction line (8) for introducing surplus drain to the makeup water tank (7) from the drain tank (4); and condensing units (33) and (39) provided for the makeup water tank (7), and configured to condense one or both of the first flush steam and a second flush steam by bringing the one or both of the first flush steam and the second flush steam into contact with the makeup water within the makeup water tank (7), the second flush steam being generated from the surplus drain.Type: GrantFiled: April 27, 2012Date of Patent: November 22, 2016Assignee: MIURA CO., LTD.Inventors: Sohei Akinaga, Tomohiro Ookubo, Tatsuki Kobayashi, Hiroyuki Hatanaka
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Publication number: 20150322024Abstract: The present invention provides a cinnamic acid amide derivative having an excellent analgesic action. The cinnamic acid amide derivative of the present invention is a compound showing excellent analgesic actions to not only a nociceptive pain model animal but also a neuropathic pain model animal, which is very useful as an agent for treating various pain diseases showing acute or chronic pains or neuropathic pains.Type: ApplicationFiled: December 27, 2013Publication date: November 12, 2015Applicant: NIPPON ZOKI PHARMACEUTICAL CO., LTD.Inventors: Tomohiro OOKUBO, Ko NAKAMURA, Yoshitaka NAKAZAWA, Hiroyoshi NANBA, Hiroyuki YOSHIDA
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Patent number: 9150510Abstract: The amino acid derivative of the present invention provides a novel compound that shows excellent analgesic action. The amino acid derivative of the present invention is a novel compound that shows excellent analgesic action to not only a model animal for nociceptive pains but also a model animal for neuropathic pains, so that the amino acid derivative is very useful as a drug for treating various pain diseases.Type: GrantFiled: September 17, 2009Date of Patent: October 6, 2015Assignee: NIPPON ZOKI PHARMACEUTICAL CO., LTD.Inventors: Tomohiro Ookubo, Ko Nakamura, Hiroyoshi Nanba, Hiroyuki Yoshida, Yoshitaka Nakazawa
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Publication number: 20150027384Abstract: To achieve a downsized drain tank without reducing an effective drain recovery rate. A closed drain recovery system includes: a steam boiler (2); a closed-type drain tank (4); an air-open-type makeup water tank (7); a steam introduction line (10) for introducing a first flush steam within the drain tank (4) to the makeup water tank (7); a surplus drain introduction line (8) for introducing surplus drain to the makeup water tank (7) from the drain tank (4); and condensing units (33) and (39) provided for the makeup water tank (7), and configured to condense one or both of the first flush steam and a second flush steam by bringing the one or both of the first flush steam and the second flush steam into contact with the makeup water within the makeup water tank (7), the second flush steam being generated from the surplus drain.Type: ApplicationFiled: April 27, 2012Publication date: January 29, 2015Inventors: Sohei Akinaga, Tomohiro Ookubo, Tatsuki Kobayashi, Hiroyuki Hatanaka
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Publication number: 20140338615Abstract: There is provided a drain recovery system with which power for driving a feedwater pump can be reduced and the feedwater pump can be driven at low costs. The drain recovery system includes: a buffer tank; an assist tank disposed below the buffer tank; a first drain supply line that connects a load device and the buffer tank; a second drain supply line that connects the buffer tank and the assist tank; a drain supply valve; a communication line that establishes communication between the assist tank and the buffer tank; a communication valve; a steam supply line that supplies steam from a boiler to the assist tank; a steam supply valve; a feedwater line that supplies drain from the assist tank to the boiler; and a feedwater pump.Type: ApplicationFiled: April 27, 2012Publication date: November 20, 2014Applicant: MIURA CO., LTD.Inventors: Sohei Akinaga, Hiroyuki Hatanaka, Koji Nagai, Tomohiro Ookubo, Tetsuji Namato
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Patent number: 8757102Abstract: A boiler according to the present invention includes: a plurality of heat transfer tubes arranged to form a cylindrical shape between an upper header and a lower header to constitute a heat transfer tube row; a boiler body cover of a cylindrical shape provided between the upper header and the lower header so as to surround the heat transfer tube row; and a heat insulating material provided to a predetermined region of a space between the heat transfer tube row and the boiler body cover.Type: GrantFiled: April 11, 2008Date of Patent: June 24, 2014Assignee: Miura Co., Ltd.Inventors: Tomohiro Ookubo, Kyousuke Ookubo, Soji Sumi
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Patent number: 8677947Abstract: A boiler system has a boiler and a combustion amount control unit. The boiler includes a boiler body, a discharge unit, a discharge passage, a feedwater preheater and a feedwater temperature measuring unit. The feedwater preheater includes a heat exchanger. The feedwater temperature measuring unit measures a feedwater temperature that is the temperature of the feedwater flowing in the heat exchanger. The combustion amount control unit controls combustion amount in the boiler, and has a feedwater temperature threshold as a threshold relating to the feedwater temperature. The combustion amount control unit minimizes the combustion amount in the boiler in a case where the feedwater temperature measured by the feedwater temperature measuring unit is the feedwater temperature threshold or lower.Type: GrantFiled: March 30, 2011Date of Patent: March 25, 2014Assignee: Miura Co., Ltd.Inventors: Tomohiro Ookubo, Takashi Morimatsu, Shigeyoshi Matsugi, Eiki Suzuki
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Patent number: 8324261Abstract: The present invention is to provide a novel compound which is useful as a pharmaceutical agent such as an analgesic. The present invention is to provide the novel histidine derivative having an excellent analgesic action and the like. The compound of the present invention has a very high intermigration into the blood upon oral administration and is very useful as a pharmaceutical agent, especially an analgesic for the treatment of acute or chronic pain diseases and of neuropathic pain diseases.Type: GrantFiled: July 18, 2008Date of Patent: December 4, 2012Assignee: Nippon Zoki Pharmaceutical Co., Ltd.Inventors: Yoshitaka Nakazawa, Kenji Mitsuda, Tomohiro Ookubo, Teppei Seguchi, Hiroyoshi Nanba
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Publication number: 20110303163Abstract: A boiler system has a boiler and a combustion amount control unit. The boiler includes a boiler body, a discharge unit, a discharge passage, a feedwater preheater and a feedwater temperature measuring unit. The feedwater preheater includes a heat exchanger. The feedwater temperature measuring unit measures a feedwater temperature that is the temperature of the feedwater flowing in the heat exchanger. The combustion amount control unit controls combustion amount in the boiler, and has a feedwater temperature threshold as a threshold relating to the feedwater temperature. The combustion amount control unit minimizes the combustion amount in the boiler in a case where the feedwater temperature measured by the feedwater temperature measuring unit is the feedwater temperature threshold or lower.Type: ApplicationFiled: March 30, 2011Publication date: December 15, 2011Applicant: MIURA CO., LTD.Inventors: Tomohiro OOKUBO, Takashi MORIMATSU, Shigeyoshi MATSUGI, Eiki SUZUKI
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Publication number: 20110172442Abstract: The amino acid derivative of the present invention provides a novel compound that shows excellent analgesic action. The amino acid derivative of the present invention is a novel compound that shows excellent analgesic action to not only a model animal for nociceptive pains but also a model animal for neuropathic pains, so that the amino acid derivative is very useful as a drug for treating various pain diseases.Type: ApplicationFiled: September 17, 2009Publication date: July 14, 2011Applicant: NIPPON ZOKI PHARMACEUTICAL CO., LTD.Inventors: Tomohiro Ookubo, Ko Nakamura, Hiroyoshi Nanba, Hiroyuki Yoshida, Yoshitaka Nakazawa
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Publication number: 20100212603Abstract: An amount of scale adhering onto inner surfaces of water tubes in any one of various boilers including a steam boiler, a hot water boiler, a waste heat boiler, and an exhaust gas boiler is accurately known by providing a temperature sensor at an appropriate position of the boiler. A plurality of water tubes (5, 6) connecting between an upper header (3) and a lower header (4) constitute an inner water tube row (7) and an outer water tube row (8). Inner longitudinal fins (9) close gaps between the adjacent inner water tubes (5, 5) except at a lower end of the inner water tube row (7). Outer longitudinal fins (11) close gaps between the adjacent outer water tubes (6, 6) except at an upper end of the outer water tube row (8).Type: ApplicationFiled: April 14, 2008Publication date: August 26, 2010Applicant: MIURA CO., LTD.Inventors: Tomohiro Ookubo, Kyosuke Ookubo
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Publication number: 20100152459Abstract: The present invention is to provide a novel compound which is useful as a pharmaceutical agent such as an analgesic. The present invention is to provide the novel histidine derivative having an excellent analgesic action and the like. The compound of the present invention has a very high intermigration into the blood upon oral administration and is very useful as a pharmaceutical agent, especially an analgesic for the treatment of acute or chronic pain diseases and of neuropathic pain diseases.Type: ApplicationFiled: July 18, 2008Publication date: June 17, 2010Applicant: NIPPON ZOKI PHARMACEUTICAL CO., LTD.Inventors: Yoshitaka Nakazawa, Kenji Mitsuda, Tomohiro Ookubo, Teppei Seguchi, Hiroyoshi Nanba
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Publication number: 20100004459Abstract: The present invention is to provide the compounds useful as a treating or preventing agent for gout and hyperuricemia which are 2-phenylnicotinic acid derivatives having a uric acid lowering action due to an excellent xanthine oxidase inhibitory action. Since the 2-phenylnicotinic acid derivatives of the present invention exhibit a uric acid lowering action due to an excellent xanthine oxidase inhibitory action and also hypolipemic action, their utility is very high as a treating or preventive agent for gout and hyperuricemia which are often accompanied by hyperlipemia as a complication.Type: ApplicationFiled: December 12, 2007Publication date: January 7, 2010Applicant: NIPPON ZOKI PHARMACEUTICAL CO., LTD.Inventors: Nobuo Menjo, Tomohiro Ookubo, Taisuke Hasegawa, Kazuhito Furukawa, Akihiro Fujita
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Publication number: 20090025659Abstract: Provided is a boiler including: a plurality of heat transfer tubes arranged to form a cylindrical shape between an upper header and a lower header to constitute a heat transfer tube row; and a plurality of longitudinal fins provided to close gaps between the heat transfer tubes without connecting the adjacent heat transfer tubes, the plurality of longitudinal fins being provided to a portion other than one of one end in a vertical direction of the heat transfer tube row and a part in a peripheral direction thereof.Type: ApplicationFiled: April 11, 2008Publication date: January 29, 2009Inventors: Tomohiro Ookubo, Kyousuke Ookubo, Keiichi Hiraoka, Soji Sumi
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Publication number: 20080257283Abstract: A boiler according to the present invention includes: a plurality of heat transfer tubes arranged to form a cylindrical shape between an upper header and a lower header to constitute a heat transfer tube row; a boiler body cover of a cylindrical shape provided between the upper header and the lower header so as to surround the heat transfer tube row; and a heat insulating material provided to a predetermined region of a space between the heat transfer tube row and the boiler body cover.Type: ApplicationFiled: April 11, 2008Publication date: October 23, 2008Inventors: Tomohiro Ookubo, Kyousuke Ookubo, Soji Sumi
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Patent number: 6269782Abstract: Boiler efficiency is further improved and the whole boiler body is slimmed down by totally improving heat transfer surfaces confronting gas flow passages, i.e., by forming the heat transfer surface structure into three stages, and moreover by making effective use of the whole heat transfer surfaces of water tubes equipped with fully circumferentially finned water tubes.Type: GrantFiled: August 1, 2000Date of Patent: August 7, 2001Assignees: Miura Co., Ltd., Miura Institute of Research & Development Co., Ltd.Inventors: Toshihiro Kayahara, Akinori Kawakami, Takashi Morimatsu, Koichi Wakae, Kanta Kondou, Tomohiro Ookubo, Osamu Tanaka