Abstract: The disclosure is directed to methods, treatment regimens, uses, kits and therapies for treating Generalized Pustular Psoriasis (GPP). These methods, treatment regimens, uses, kits and therapies utilize, inter alia, administration of an IL-17 antagonist, e.g., an IL-17 antibody, such as secukinumab. Additionally disclosed are improved methods for treating plaque-type psoriasis that utilize up-titration and down-titration of the IL-17 antagonist, e.g., an IL-17 antibody, such as secukinumab, as well as modification of dose frequency. Further disclosed are methods of treating palmoplantar pustular psoriasis using the disclosed IL-17 antagonists, e.g., IL-17 antibodies, such as secukinumab.

Abstract: A resin shaping mold includes a hot runner, a cavity, a cold runner, and a valve pin. The cold runner is connected to the hot runner and the cavity. The cold runner has a lower temperature than the hot runner. The valve pin configured to move forward and backward from the hot runner toward the cold runner and close a channel of molten resin from the hot runner to the cavity at a predetermined position. The valve pin includes a runner lock portion configured to hold resin solidified at a position further on the cavity side with respect to the predetermined position in the cold runner.

Abstract: A system for assisting sharing of information includes circuitry to: input a plurality of sentences each representing a statement made by one of a plurality of users, the sentence being generated by speaking or writing during a meeting or by extracting from at least one of meeting data, email data, electronic file data, and chat data at any time; determine a statement type of the statement represented by each one of the plurality of sentences, the statement type being one of a plurality of statement types previously determined; select, from among the plurality of sentences being input, one or more sentences each representing a statement of a specific statement type of the plurality of types; and output a list of the selected one or more sentences as key statements of the plurality of sentences.

Abstract: A filler-containing resin molded product with a surface which includes irregularities which are transferred from a mold cavity to the surface and have an arithmetic mean roughness of 0.8 ?m or greater and 10 ?m or less and a peak arithmetic mean curvature of 400 [1/mm] or greater and 900 [1/mm] or less.

Abstract: A conference support system is for supporting a conference. The conference support system includes one or more information processing apparatuses for implementing various functions of the conference support system. The conference support system includes an inputter configured to input a statement content that is a content of a statement stated by a participant of the conference; a determiner configured to determine a statement type of the statement content, based on the statement content input by the inputter; and an outputter configured to output at least one of the statement content, an evaluation of the conference, and an evaluation of the participant, based on a determination result obtained by the determiner.

Abstract: The disclosure is directed to methods, treatment regimens, uses, kits and therapies for treating Generalized Pustular Psoriasis (GPP). These methods, treatment regimens, uses, kits and therapies utilize, inter alia, administration of an IL-17 antagonist, e.g., an IL-17 antibody, such as secukinumab. Additionally disclosed are improved methods for treating plaque-type psoriasis that utilize up-titration and down-titration of the IL-17 antagonist, e.g., an IL-17 antibody, such as secukinumab, as well as modification of dose frequency. Further disclosed are methods of treating palmoplantar pustular psoriasis using the disclosed IL-17 antagonists, e.g., IL-17 antibodies, such as secukinumab.

Abstract: A data transfer apparatus includes a virtual channel unit configured to time share a serial bus for a first virtual channel and a second virtual channel and include a buffering control unit configured to receive data via the first virtual channel and the second virtual channel, first and second receive buffers being configured to store the data received via the first virtual channel and the second virtual channel, respectively; and a switching unit configured to control storing the data received via the first virtual channel in the second receive buffer when the buffering control unit receives the data from another data transfer apparatus which is configured to use only the first virtual channel and the capacity of the first receive buffer is smaller than that of the second receive buffer.

Abstract: A data transfer device includes a serial interface including plural transmission paths and carrying out a data transfer operation with plural operating frequencies, transfer requesting units issuing a data transfer request to the serial interface, a request monitoring unit, a condition setting unit setting a set transmission path condition including at least one of a number of the transmission paths and an operating frequency used when the data transfer requests are issued to switch statuses of the data transfer requests to statuses of switching data transfer requests, a use transmission path condition determining unit determining the set transmission path condition corresponding to the status of the switching data transfer request as a use transmission path condition when the status of switching data transfer request corresponds to the status of data transfer request by comparing the statuses, and a switching unit switching to the use transmission path condition.

Abstract: A data transfer apparatus includes a virtual channel unit configured to time share a serial bus for a first virtual channel and a second virtual channel and include a buffering control unit configured to receive data via the first virtual channel and the second virtual channel, first and second receive buffers being configured to store the data received via the first virtual channel and the second virtual channel, respectively; and a switching unit configured to control storing the data received via the first virtual channel in the second receive buffer when the buffering control unit receives the data from another data transfer apparatus which is configured to use only the first virtual channel and the capacity of the first receive buffer is smaller than that of the second receive buffer.

Abstract: A data transfer device includes a serial interface including plural transmission paths and carrying out a data transfer operation with plural operating frequencies, transfer requesting units issuing a data transfer request to the serial interface, a request monitoring unit, a condition setting unit setting a set transmission path condition including at least one of a number of the transmission paths and an operating frequency used when the data transfer requests are issued to switch statuses of the data transfer requests to statuses of switching data transfer requests, a use transmission path condition determining unit determining the set transmission path condition corresponding to the status of the switching data transfer request as a use transmission path condition when the status of switching data transfer request corresponds to the status of data transfer request by comparing the statuses, and a switching unit switching to the use transmission path condition.

Abstract: An ASIC includes a receiving unit, a transmission interface, a reception interface, a buffer, and a control unit. When the receiving unit receives a second write request while the transmission interface is in process of transmitting to a transmission line a first write request and write data, the control unit causes the receiving unit to store the second write request in the buffer. When the receiving unit receives a read request while the second write request is present in the buffer, the control unit causes the receiving unit to send the read request to the transmission interface prior to the second write request.

Abstract: An ASIC includes a receiving unit, a transmission interface, a reception interface, a buffer, and a control unit. When the receiving unit receives a second write request while the transmission interface is in process of transmitting to a transmission line a first write request and write data, the control unit causes the receiving unit to store the second write request in the buffer. When the receiving unit receives a read request while the second write request is present in the buffer, the control unit causes the receiving unit to send the read request to the transmission interface prior to the second write request.