Abstract: The present invention relates to a transdermal absorption preparation that can maintain a blood concentration sufficient to exert the efficacy of tandospirone, and also shows good storage stability against heat, humidity, and light. According to the present invention, a transdermal absorption preparation containing tandospirone or a pharmaceutically acceptable salt thereof, and levulinic acid, which is superior in the skin permeability of tandospirone or a pharmaceutically acceptable salt thereof in the preparation, and shows good preservation stability against heat and light can be provided.

Abstract: Provided is a transdermal absorption preparation having superior drug skin permeability, which can uniformly disperse the drug in the preparation and maintain the uniform dispersion state of the drug. A transdermal absorption preparation having a plaster layer containing a drug, a polymer and a pH adjuster, in which the aforementioned polymer contains a polymer having a particular glass transition temperature of 30° C.-200° C., and the surface of the plaster layer has a pH of 6.7-10.0.

Abstract: Provided is a transdermal absorption preparation that shows superior skin permeability of a drug and that does not easily cause cold flow. A transdermal absorption preparation having a drug-containing layer containing a drug and a polymer, wherein 50-100 wt % of the polymer in the drug-containing layer is a polymer having a glass transition temperature of 30° C.-200° C., and the drug in the drug-containing layer is in an amorphous state.

Abstract: Provided are a production method of a pregabalin-containing composition, which suppresses crystallization of pregabalin, and a pregabalin-containing composition that shows suppressed crystallization of Pregabalin. The production method of the pregabalin-containing composition of the present invention contains steps of: (1) dissolving pregabalin in an aqueous solution of an acid to prepare an aqueous solution of a salt of pregabalin; (2) mixing the aqueous solution of pregabalin salt and a hydrophilic resin to prepare a mixture thereof; and (3) concentrating the mixture; wherein the acid has an acid dissociation constant lower than that of pregabalin.

Abstract: A transdermal absorption preparation precursor 50 containing a release liner 10 containing one first valley fold part 1, one or two first mountain fold parts 2, and a first base line L1 and a second base line L2 on one side and the other side apart from the first valley fold part 1 as a line of demarcation and at an approximately equal distance from the first valley fold part 1, wherein at least one of the first base line L1 and the second base line L2 is a fold line of the first mountain fold part 2, and a drug-containing layer 3 having a center line laid on the first base line L1 and an adhesive layer 4 having a center line laid on the second base line L2 on the release liner 10.

Abstract: Provided are a production method of a pregabalin-containing composition, which suppresses crystallization of pregabalin, and a pregabalin-containing composition that shows suppressed crystallization of Pregabalin. The production method of the pregabalin-containing composition of the present invention contains steps of: (1) dissolving pregabalin in an aqueous solution of an acid to prepare an aqueous solution of a salt of pregabalin; (2) mixing the aqueous solution of pregabalin salt and a hydrophilic resin to prepare a mixture thereof; and (3) concentrating the mixture; wherein the acid has an acid dissociation constant lower than that of pregabalin.

Abstract: Provided is a transdermal absorption preparation having superior drug skin permeability, which can uniformly disperse the drug in the preparation and maintain the uniform dispersion state of the drug. A transdermal absorption preparation having a plaster layer containing a drug, a polymer and a pH adjuster, in which the aforementioned polymer contains a polymer having a particular glass transition temperature of 30° C.-200° C., and the surface of the plaster layer has a pH of 6.7-10.0.

Abstract: A transdermal absorption preparation precursor 50 containing a release liner 10 containing one first valley fold part 1, one or two first mountain fold parts 2, and a first base line L1 and a second base line L2 on one side and the other side apart from the first valley fold part 1 as a line of demarcation and at an approximately equal distance from the first valley fold part 1, wherein at least one of the first base line L1 and the second base line L2 is a fold line of the first mountain fold part 2, and a drug-containing layer 3 having a center line laid on the first base line L1 and an adhesive layer 4 having a center line laid on the second base line L2 on the release liner 10.

Abstract: Provided is a transdermal absorption preparation that shows superior skin permeability of a drug and that does not easily cause cold flow. A transdermal absorption preparation having a drug-containing layer containing a drug and a polymer, wherein 50-100 wt % of the polymer in the drug-containing layer is a polymer having a glass transition temperature of 30° C.-200° C., and the drug in the drug-containing layer is in an amorphous state.

Abstract: The present invention provides a patch preparation that has an extremely low moisture permeability, has a sufficient ODT effect, is excellent in drug releasability, and has a preferred handleability. The patch preparation of the present invention includes a support; and a pressure-sensitive adhesive layer containing an adherent polymer and a drug on one surface of the support, wherein: the support has a polyester base layer, an inorganic oxide layer, and a polyester nonwoven fabric layer in the stated order; the polyester base layer has a thickness of 1.0 ?m to 16 ?m; and the pressure-sensitive adhesive layer is laminated on the polyester base layer.

Abstract: There is provided a light diffusing element made of a thin film capable of realizing low back scattering and a high haze. A light diffusing element according to an embodiment of the invention includes: a first region having a first refractive index n1; a refractive index modulation region having a substantially spherical shell shape and surrounding the first region; and a second region having a second refractive index n2, the second region being positioned on a side of the refractive index modulation region opposite to the first region. The light diffusing element satisfies the following expressions (1) and (2): 0.0006??n/L??(1) 10?(?n)2×A×B?100??(2).

Abstract: Disclosed is a material roll that includes a roll of an optical film having defect information markings printed thereon and is resistant to the formation of a defect by the transfer of a bump/dent deformation at the marking site. The material roll includes a long sheet of an optical film with polarizer wound into roll shape; and marking(s) formed at or in a vicinity of at least one defect site. The marking has an optical density of 1.5 or more, and a thickness of a center part of the marking is 1.5 ?m or less. The marking preferably has an optical density per unit thickness of 2.5 ?m?1 or more.

Abstract: Disclosed is a material roll that includes a roll of an optical film having defect information markings printed thereon and is resistant to the formation of a defect by the transfer of a bump/dent deformation at the marking site. The material roll includes a long sheet of an optical film with polarizer wound into roll shape; and marking(s) formed at or in a vicinity of at least one defect site. The marking has an optical density of 1.5 or more, and a thickness of a center part of the marking is 1.5 ?m or less. The marking preferably has an optical density per unit thickness of 2.5 ?m?1 or more.

Abstract: The present invention provides a patch preparation that has an extremely low moisture permeability, has a sufficient ODT effect, is excellent in drug releasability and in anchoring property of its drug-containing pressure-sensitive adhesive layer, and has a preferred patch feeling. The patch preparation of the present invention includes a support; and a pressure-sensitive adhesive layer containing an adherent polymer and a drug on one surface of the support, wherein: the support has a polyester base layer, an inorganic oxide layer, and a polyester nonwoven fabric layer in the stated order; the polyester base layer has a thickness of 1.0 ?m to 16 ?m; and the pressure-sensitive adhesive layer is laminated on the polyester nonwoven fabric layer.

Abstract: The present invention provides a patch preparation that has an extremely low moisture permeability, has a sufficient ODT effect, is excellent in drug releasability, and has a preferred handleability. The patch preparation of the present invention includes a support; and a pressure-sensitive adhesive layer containing an adherent polymer and a drug on one surface of the support, wherein: the support has a polyester base layer, an inorganic oxide layer, and a polyester nonwoven fabric layer in the stated order; the polyester base layer has a thickness of 1.0 ?m to 16 ?m; and the pressure-sensitive adhesive layer is laminated on the polyester base layer.

Abstract: A light diffusing element having less unevenness in external appearance while having excellent light diffusibility.

Abstract: There is provided a light diffusing element made of a thin film capable of realizing low back scattering and a high haze. A light diffusing element according to an embodiment of the invention includes: a first region having a first refractive index n1; a refractive index modulation region having a substantially spherical shell shape and surrounding the first region; and a second region having a second refractive index n2, the second region being positioned on a side of the refractive index modulation region opposite to the first region.

Abstract: A video image appreciation system 10 of the present invention comprises: a self-luminous display 30; and a circularly-polarized light source 11, wherein the self-luminous display 30 comprises in order: (a) a first wavelength plate 13 having functions to convert circularly-polarized light into linearly-polarized light and vice versa; (b) a polarizing film 15; (c) a linearly-polarized separation film 20; (d) a second wavelength plate 18 having functions to convert circularly-polarized light into linearly-polarized light and vice versa; and (e) a self-luminous panel 16.

Abstract: A video viewing facility is provided. A circularly polarized light source is provided outside a self-luminous display. The self-luminous display includes a first wave plate having a function of converting circularly polarized light into linearly polarized light; a polarizing film; a second wave plate having a function of converting circularly polarized light into linearly polarized light; a circularly polarized light separating film; and a self-luminous panel, in this order from a visible side of the self-luminous display.

Abstract: The present invention provides a patch preparation that has an extremely low moisture permeability, has a sufficient ODT effect, is excellent in drug releasability and in anchoring property of its drug-containing pressure-sensitive adhesive layer, and has a preferred patch feeling. The patch preparation of the present invention includes a support; and a pressure-sensitive adhesive layer containing an adherent polymer and a drug on one surface of the support, wherein: the support has a polyester base layer, an inorganic oxide layer, and a polyester nonwoven fabric layer in the stated order; the polyester base layer has a thickness of 1.0 ?m to 16 ?m; and the pressure-sensitive adhesive layer is laminated on the polyester nonwoven fabric layer.