Patents by Inventor Tomokazu Hino

Tomokazu Hino has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10391076
    Abstract: The present invention relates to an anticancer agent having a high safety and a superior anticancer activity, and anticancer agent containing, as an active ingredient, an aminoacetonitrile compound represented by the formula (I) wherein R1 is a hydrogen atom, an alkyl group and the like, R2, R3, and R4 are the same or different and each is a hydrogen atom, an alkyl group and the like, R5 and R6 are the same or different and each is a hydrogen atom, a halogen atom and the like, m is 0 or 1, R is a halogen atom, a cyano group, a nitro group, a phenyl group optionally substituted by an alkyl group and the like, an alkyl group and the like, Ar1 is a phenyl group, a naphthyl group, a pyridyl group, a pyrazolyl group, or the like, each of which is optionally substituted by a halogen atom, a cyano group, a nitro group, alkyl group and the like, and W is —O—, —S—, —SO2—, or —N(R7)— wherein R7 is a hydrogen atom, a (C1-C6)alkyl group and the like, or a pharmacologically acceptable salt thereof.
    Type: Grant
    Filed: February 24, 2016
    Date of Patent: August 27, 2019
    Assignee: Pitney Pharmaceuticals Pty Ltd.
    Inventors: Nobuharu Andoh, Osamu Sanpei, Tetsuo Toga, David Lawson Morris, Roger Aston, Koji Tanaka, Tomokazu Hino
  • Patent number: 10292960
    Abstract: The present invention relates to an anticancer agent having a high safety and a superior anticancer activity, and an anticancer agent containing, as an active ingredient, an aminoacetonitrile compound represented by the formula (I) wherein R1 is a hydrogen atom, an alkyl group and the like, R2, R3, and R4 are the same or different and each is a hydrogen atom, an alkyl group and the like, R5 and R6 are the same or different and each is a hydrogen atom, a halogen atom and the like, m is 0 or 1, R is a halogen atom, a cyano group, a nitro group, a phenyl group optionally substituted by an alkyl group and the like, an alkyl group and the like, Ar1 is a phenyl group, a naphthyl group, a pyridyl group, a pyrazolyl group, or the like, each of which is optionally substituted by a halogen atom, a cyano group, a nitro group, alkyl group and the like, and W is —O—, —S—, —SO2—, or —N(R7)— wherein R7 is a hydrogen atom, a (C1-C6) alkyl group and the like, or a pharmacologically acceptable salt thereof.
    Type: Grant
    Filed: January 23, 2018
    Date of Patent: May 21, 2019
    Assignee: PITNEY PHARMACEUTICALS PTY LIMITED
    Inventors: Nobuharu Andoh, Osamu Sanpei, Tetsuo Toga, David Morris, Roger Aston, Koji Tanaka, Tomokazu Hino
  • Publication number: 20180243255
    Abstract: The present invention relates to an anticancer agent having a high safety and a superior anticancer activity, and anticancer agent containing, as an active ingredient, an aminoacetonitrile compound represented by the formula (I) wherein R1 is a hydrogen atom, an alkyl group and the like, R2, R3, and R4 are the same or different and each is a hydrogen atom, an alkyl group and the like, R5 and R6 are the same or different and each is a hydrogen atom, a halogen atom and the like, m is 0 or 1, R is a halogen atom, a cyano group, a nitro group, a phenyl group optionally substituted by an alkyl group and the like, an alkyl group and the like, Ar1 is a phenyl group, a naphthyl group, a pyridyl group, a pyrazolyl group, or the like, each of which is optionally substituted by a halogen atom, a cyano group, a nitro group, alkyl group and the like, and W is —O—, —S—, —SO2—, or —N(R7)— wherein R7 is a hydrogen atom, a (C1-C6)alkyl group and the like, or a pharmacologically acceptable salt thereof.
    Type: Application
    Filed: February 24, 2016
    Publication date: August 30, 2018
    Applicant: Pitney Pharmaceuticals Pty Limited
    Inventors: Nobuharu ANDOH, Osamu SANPEI, Tetsuo TOGA, David Lawson MORRIS, Roger ASTON, Koji TANAKA, Tomokazu HINO
  • Publication number: 20180207124
    Abstract: The present invention relates to an anticancer agent having a high safety and a superior anticancer activity, and an anticancer agent containing, as an active ingredient, an aminoacetonitrile compound represented by the formula (I) wherein R1 is a hydrogen atom, an alkyl group and the like, R2, R3, and R4 are the same or different and each is a hydrogen atom, an alkyl group and the like, R5 and R6 are the same or different and each is a hydrogen atom, a halogen atom and the like, m is 0 or 1, R is a halogen atom, a cyano group, a nitro group, a phenyl group optionally substituted by an alkyl group and the like, an alkyl group and the like, Ar1 is a phenyl group, a naphthyl group, a pyridyl group, a pyrazolyl group, or the like, each of which is optionally substituted by a halogen atom, a cyano group, a nitro group, alkyl group and the like, and W is —O—, —S—, —SO2—, or —N(R7)—wherein R7 is a hydrogen atom, a (C1-C6) alkyl group and the like, or a pharmacologically acceptable salt thereof.
    Type: Application
    Filed: January 23, 2018
    Publication date: July 26, 2018
    Applicant: PITNEY PHARMACEUTICALS PTY LIMITED
    Inventors: Nobuharu ANDOH, Osamu SANPEI, Tetsuo TOGA, David MORRIS, Roger ASTON, Koji TANAKA, Tomokazu HINO
  • Patent number: 9907778
    Abstract: The present invention relates to an anticancer agent having a high safety and a superior anticancer activity, and an anticancer agent containing, as an active ingredient, an aminoacetonitrile compound represented by the formula (I) wherein R1 is a hydrogen atom, an alkyl group and the like, R2, R3, and R4 are the same or different and each is a hydrogen atom, an alkyl group and the like, R5 and R6 are the same or different and each is a hydrogen atom, a halogen atom and the like, m is 0 or 1, R is a halogen atom, a cyano group, a nitro group, a phenyl group optionally substituted by an alkyl group and the like, an alkyl group and the like, Ar1 is a phenyl group, a naphthyl group, a pyridyl group, a pyrazolyl group, or the like, each of which is optionally substituted by a halogen atom, a cyano group, a nitro group, alkyl group and the like, and W is —O—, —S—, —SO2—, or —N(R7)— wherein R7 is a hydrogen atom, a (C1-C6)alkyl group and the like, or a pharmacologically acceptable salt thereof.
    Type: Grant
    Filed: September 12, 2014
    Date of Patent: March 6, 2018
    Assignee: Pitney Pharmaceuticals Pty Limited
    Inventors: Nobuharu Andoh, Osamu Sanpei, Tetsuo Toga, David Lawson Morris, Roger Aston, Koji Tanaka, Tomokazu Hino
  • Publication number: 20160213640
    Abstract: The present invention relates to an anticancer agent having a high safety and a superior anticancer activity, and an anticancer agent containing, as an active ingredient, an aminoacetonitrile compound represented by the formula (I) wherein R1 is a hydrogen atom, an alkyl group and the like, R2, R3, and R4 are the same or different and each is a hydrogen atom, an alkyl group and the like, R5 and R6 are the same or different and each is a hydrogen atom, a halogen atom and the like, m is 0 or 1, R is a halogen atom, a cyano group, a nitro group, a phenyl group optionally substituted by an alkyl group and the like, an alkyl group and the like, Ar1 is a phenyl group, a naphthyl group, a pyridyl group, a pyrazolyl group, or the like, each of which is optionally substituted by a halogen atom, a cyano group, a nitro group, alkyl group and the like, and W is —O—, —S—, —SO2—, or —N(R7)— wherein R7 is a hydrogen atom, a (C1-C6)alkyl group and the like, or a pharmacologically acceptable salt thereof.
    Type: Application
    Filed: September 12, 2014
    Publication date: July 28, 2016
    Applicants: NIHON NOHYAKU CO., LTD., PITNEY PHARMACEUTICALS PTY LIMITED
    Inventors: Nobuharu ANDOH, Osamu SANPEI, Tetsuo TOGA, David Lawson MORRIS, Roger ASTON, Koji TANAKA, Tomokazu HINO
  • Patent number: 8444282
    Abstract: A display device capable of expressing a particularly superior red color, for example, a red color of the sRGB standard, is provided. A display device 1 is composed of a red fluorescent body in which the red chromaticity point (xR, yR) satisfies xR?20.640 and yR?0.330, and a green fluorescent body.
    Type: Grant
    Filed: November 7, 2007
    Date of Patent: May 21, 2013
    Assignee: Sony Corporation
    Inventors: Takahiro Igarashi, Tsuneo Kusunoki, Takashi Tamura, Tomokazu Hino
  • Patent number: 8137584
    Abstract: Disclosed is a luminescent composition containing a fluorescent body having Eu2+ as a luminescent center. The luminescent composition is obtained by a process including the steps of mixing a raw material of the fluorescent body with an organic compound having elements other than oxygen, and sintering the mixture to form the fluorescent body from the raw material.
    Type: Grant
    Filed: October 29, 2007
    Date of Patent: March 20, 2012
    Assignee: Sony Corporation
    Inventors: Takashi Tamura, Tomokazu Hino, Tsuneo Kusunoki, Takahiro Igarashi
  • Patent number: 8048825
    Abstract: A haloalkylsulfonanilide derivative represented by general formula (I) or a salt thereof wherein R1 represents a halo(C1-C8)alkyl group, R2, R3, R4, R5, R6, R7, R8, R9 and R10 represent hydrogen atoms, etc., n represents 1 or 2, A represents an oxygen atom, W represents an oxygen atom, X represents a halogen atom and m represents an integer of 0 to 4, are compounds useful as herbicides having both of remarkable herbicidal effect and characteristics such as excellent crop-weed selectivity.
    Type: Grant
    Filed: November 16, 2007
    Date of Patent: November 1, 2011
    Assignee: Nihon Nohyaku Co., Ltd.
    Inventors: Tomokazu Hino, Yasuko Yamada, Toshihiko Shigenari, Koki Mametsuka
  • Publication number: 20100308711
    Abstract: The present invention is to provide a luminescent composition, a light source device, and a display device each having a phosphor for which both avoidance of the shift of the luminescence wavelength band toward the shorter wavelength side and suppression of color unevenness are achieved. A configuration is provided in which a luminescent composition having a phosphor with the same crystal structure as that of CaAlSiN3 contains carbon at a ratio of at least 0.05 weight % or higher.
    Type: Application
    Filed: July 30, 2007
    Publication date: December 9, 2010
    Applicant: SONY CORPORATION
    Inventors: Takashi Tamura, Tomokazu Hino, Tsuneo Kusunoki, Takahiro Igarashi
  • Publication number: 20100016164
    Abstract: A haloalkylsulfonanilide derivative represented by general formula (I) or a salt thereof wherein R1 represents a halo(C1-C8)alkyl group, R2, R3, R4, R5, R6, R7, R8, R9 and R10 represent hydrogen atoms, etc., n represents 1 or 2, A represents an oxygen atom, W represents an oxygen atom, X represents a halogen atom and m represents an integer of 0 to 4, are compounds useful as herbicides having both of remarkable herbicidal effect and characteristics such as excellent crop-weed selectivity.
    Type: Application
    Filed: November 16, 2007
    Publication date: January 21, 2010
    Inventors: Tomokazu Hino, Yasuko Yamada, Toshihiko Shigenari, Koki Mametsuka
  • Publication number: 20100002413
    Abstract: A display device capable of expressing a particularly superior red color, for example, a red color of the sRGB standard, is provided. A display device 1 is composed of a red fluorescent body in which the red chromaticity point (xR, yR) satisfies xR?20.640 and yR?0.330, and a green fluorescent body.
    Type: Application
    Filed: November 7, 2007
    Publication date: January 7, 2010
    Applicant: Sony Corporation
    Inventors: Takahiro Igarashi, Tsuneo Kusunoki, Takashi Tamura, Tomokazu Hino
  • Publication number: 20080274892
    Abstract: A haloalkylsulfonanilide derivative represented by the formula (I): {wherein R1 represents haloalkyl; R2 represents H, alkylcarbonyl, optionally substituted phenylcarbonyl, alkoxycarbonyl, optionally substituted phenoxycarbonyl, optionally substituted phenylsulfonyl, etc.; R3 and R4 each represents H, alkyl, cycloalkyl, halogeno, CN, etc.; R5, R6, R7, and R8 each represents H, halogeno, alkyl, cycloalkyl, optionally substituted phenyl(C1-6 alkyl), an optionally substituted heterocycle, etc.; A and W each represents O or S; and X represents one to four substituents selected among H, halogeno, alkyl, alkenyl, optionally substituted phenyl, optionally substituted phenylalkylaminocarbonyl, OH, CN, etc.} and a salt thereof; and a herbicide containing any of these compounds as an active ingredient. The herbicide is excellent in wide applicability, persistency, and selectivity for crops and effectiveness against weeds. It is excellent especially as a herbicide for rice fields.
    Type: Application
    Filed: February 23, 2006
    Publication date: November 6, 2008
    Inventors: Tomokazu Hino, Toshihiko Shigenari, Takahiro Kiyokawa, Koki Mametsuka, Yasuko Yamada
  • Publication number: 20080258112
    Abstract: Disclosed is a luminescent composition containing a fluorescent body having Eu2+as a luminescent center. The luminescent composition is obtained by a process including the steps of mixing a raw material of the fluorescent body with an organic compound having elements other than oxygen, and sintering the mixture to form the fluorescent body from the raw material.
    Type: Application
    Filed: October 29, 2007
    Publication date: October 23, 2008
    Applicant: SONY CORPORATION
    Inventors: Takashi Tamura, Tomokazu Hino, Tsuneo Kusunoki, Takahiro Igarashi
  • Patent number: 7057067
    Abstract: The present invention provides a process for producing 2-halobenzoic acids of the general formula (I), characterized by reacting a benzoic acid of formula (II) with a halogenating agent in the presence of Pd catalyst: (wherein A is —OH, —OM (M is alkali metal), —N(R6)R7 (R6 and R7 are each H, C1–C6 alkyl, optionally substituted phenyl, or the like); R is H, C1–C6 alkyl, C1–C6 alkylcarbonyl, carboxyl, C1–C12 alkoxycarbonyl, optionally substituted phenylcarbonyl, or the like; n is 0 to 4; X is Cl, Br or I, or alternatively (R)n may be present on benzene-constituting carbon atoms adjacent to each other and form a C3–C4 alkylene- or C3–C4 alkenylene-fused ring).
    Type: Grant
    Filed: April 27, 2001
    Date of Patent: June 6, 2006
    Assignee: Nihon Nohyaku Co., Ltd.
    Inventors: Hiroki Kodama, Takeshi Katsuhira, Tateki Nishida, Tomokazu Hino, Kenji Tsubata
  • Publication number: 20030181759
    Abstract: The present invention provides a process for producing 2-halobenzoic acids of the general formula (I), characterized by reacting a benzoic acid of formula (II) with a halogenating agent in the presence of Pd catalyst: 1
    Type: Application
    Filed: May 29, 2003
    Publication date: September 25, 2003
    Inventors: Hiroki Kodama, Takeshi Katsuhira, Tateki Nishida, Tomokazu Hino, Kenji Tsubata
  • Patent number: 5358965
    Abstract: The present invention relates to a hydrazone derivative represented by the general formula (I) shown below: ##STR1## wherein the substituents are as defined in the specification, processes for preparing the derivative, and uses of the derivative as an insecticide.The hydrazone derivative has a marked insecticidal effect on insect pests, especially against LEPIDOPTERA and COLEOPTERA.
    Type: Grant
    Filed: May 28, 1993
    Date of Patent: October 25, 1994
    Assignee: Nihon Nohyaku Co., Ltd.
    Inventors: Tomokazu Hino, Nobuharu Andoh, Hiroshi Hamaguchi, Atsushi Kanaoka
  • Patent number: 5304573
    Abstract: The present invention relates to a hydrazone derivative represented by the general formula (I) shown below: ##STR1## wherein the substituents are as defined in the specification, processes for preparing the derivative, and uses of the derivative as an insecticide.The hydrazone derivative has a marked insecticidal effect on insect pests, especially against LEPIDOPTERA and COLEOPTERA.
    Type: Grant
    Filed: November 13, 1991
    Date of Patent: April 19, 1994
    Assignee: Nihon Nohyaku Co., Ltd.
    Inventors: Tomokazu Hino, Nobuharu Andoh, Hiroshi Hamaguchi, Atsushi Kanaoka