Patents by Inventor Tomokazu Hino
Tomokazu Hino has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 10391076Abstract: The present invention relates to an anticancer agent having a high safety and a superior anticancer activity, and anticancer agent containing, as an active ingredient, an aminoacetonitrile compound represented by the formula (I) wherein R1 is a hydrogen atom, an alkyl group and the like, R2, R3, and R4 are the same or different and each is a hydrogen atom, an alkyl group and the like, R5 and R6 are the same or different and each is a hydrogen atom, a halogen atom and the like, m is 0 or 1, R is a halogen atom, a cyano group, a nitro group, a phenyl group optionally substituted by an alkyl group and the like, an alkyl group and the like, Ar1 is a phenyl group, a naphthyl group, a pyridyl group, a pyrazolyl group, or the like, each of which is optionally substituted by a halogen atom, a cyano group, a nitro group, alkyl group and the like, and W is —O—, —S—, —SO2—, or —N(R7)— wherein R7 is a hydrogen atom, a (C1-C6)alkyl group and the like, or a pharmacologically acceptable salt thereof.Type: GrantFiled: February 24, 2016Date of Patent: August 27, 2019Assignee: Pitney Pharmaceuticals Pty Ltd.Inventors: Nobuharu Andoh, Osamu Sanpei, Tetsuo Toga, David Lawson Morris, Roger Aston, Koji Tanaka, Tomokazu Hino
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Patent number: 10292960Abstract: The present invention relates to an anticancer agent having a high safety and a superior anticancer activity, and an anticancer agent containing, as an active ingredient, an aminoacetonitrile compound represented by the formula (I) wherein R1 is a hydrogen atom, an alkyl group and the like, R2, R3, and R4 are the same or different and each is a hydrogen atom, an alkyl group and the like, R5 and R6 are the same or different and each is a hydrogen atom, a halogen atom and the like, m is 0 or 1, R is a halogen atom, a cyano group, a nitro group, a phenyl group optionally substituted by an alkyl group and the like, an alkyl group and the like, Ar1 is a phenyl group, a naphthyl group, a pyridyl group, a pyrazolyl group, or the like, each of which is optionally substituted by a halogen atom, a cyano group, a nitro group, alkyl group and the like, and W is —O—, —S—, —SO2—, or —N(R7)— wherein R7 is a hydrogen atom, a (C1-C6) alkyl group and the like, or a pharmacologically acceptable salt thereof.Type: GrantFiled: January 23, 2018Date of Patent: May 21, 2019Assignee: PITNEY PHARMACEUTICALS PTY LIMITEDInventors: Nobuharu Andoh, Osamu Sanpei, Tetsuo Toga, David Morris, Roger Aston, Koji Tanaka, Tomokazu Hino
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Publication number: 20180243255Abstract: The present invention relates to an anticancer agent having a high safety and a superior anticancer activity, and anticancer agent containing, as an active ingredient, an aminoacetonitrile compound represented by the formula (I) wherein R1 is a hydrogen atom, an alkyl group and the like, R2, R3, and R4 are the same or different and each is a hydrogen atom, an alkyl group and the like, R5 and R6 are the same or different and each is a hydrogen atom, a halogen atom and the like, m is 0 or 1, R is a halogen atom, a cyano group, a nitro group, a phenyl group optionally substituted by an alkyl group and the like, an alkyl group and the like, Ar1 is a phenyl group, a naphthyl group, a pyridyl group, a pyrazolyl group, or the like, each of which is optionally substituted by a halogen atom, a cyano group, a nitro group, alkyl group and the like, and W is —O—, —S—, —SO2—, or —N(R7)— wherein R7 is a hydrogen atom, a (C1-C6)alkyl group and the like, or a pharmacologically acceptable salt thereof.Type: ApplicationFiled: February 24, 2016Publication date: August 30, 2018Applicant: Pitney Pharmaceuticals Pty LimitedInventors: Nobuharu ANDOH, Osamu SANPEI, Tetsuo TOGA, David Lawson MORRIS, Roger ASTON, Koji TANAKA, Tomokazu HINO
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Publication number: 20180207124Abstract: The present invention relates to an anticancer agent having a high safety and a superior anticancer activity, and an anticancer agent containing, as an active ingredient, an aminoacetonitrile compound represented by the formula (I) wherein R1 is a hydrogen atom, an alkyl group and the like, R2, R3, and R4 are the same or different and each is a hydrogen atom, an alkyl group and the like, R5 and R6 are the same or different and each is a hydrogen atom, a halogen atom and the like, m is 0 or 1, R is a halogen atom, a cyano group, a nitro group, a phenyl group optionally substituted by an alkyl group and the like, an alkyl group and the like, Ar1 is a phenyl group, a naphthyl group, a pyridyl group, a pyrazolyl group, or the like, each of which is optionally substituted by a halogen atom, a cyano group, a nitro group, alkyl group and the like, and W is —O—, —S—, —SO2—, or —N(R7)—wherein R7 is a hydrogen atom, a (C1-C6) alkyl group and the like, or a pharmacologically acceptable salt thereof.Type: ApplicationFiled: January 23, 2018Publication date: July 26, 2018Applicant: PITNEY PHARMACEUTICALS PTY LIMITEDInventors: Nobuharu ANDOH, Osamu SANPEI, Tetsuo TOGA, David MORRIS, Roger ASTON, Koji TANAKA, Tomokazu HINO
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Patent number: 9907778Abstract: The present invention relates to an anticancer agent having a high safety and a superior anticancer activity, and an anticancer agent containing, as an active ingredient, an aminoacetonitrile compound represented by the formula (I) wherein R1 is a hydrogen atom, an alkyl group and the like, R2, R3, and R4 are the same or different and each is a hydrogen atom, an alkyl group and the like, R5 and R6 are the same or different and each is a hydrogen atom, a halogen atom and the like, m is 0 or 1, R is a halogen atom, a cyano group, a nitro group, a phenyl group optionally substituted by an alkyl group and the like, an alkyl group and the like, Ar1 is a phenyl group, a naphthyl group, a pyridyl group, a pyrazolyl group, or the like, each of which is optionally substituted by a halogen atom, a cyano group, a nitro group, alkyl group and the like, and W is —O—, —S—, —SO2—, or —N(R7)— wherein R7 is a hydrogen atom, a (C1-C6)alkyl group and the like, or a pharmacologically acceptable salt thereof.Type: GrantFiled: September 12, 2014Date of Patent: March 6, 2018Assignee: Pitney Pharmaceuticals Pty LimitedInventors: Nobuharu Andoh, Osamu Sanpei, Tetsuo Toga, David Lawson Morris, Roger Aston, Koji Tanaka, Tomokazu Hino
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Publication number: 20160213640Abstract: The present invention relates to an anticancer agent having a high safety and a superior anticancer activity, and an anticancer agent containing, as an active ingredient, an aminoacetonitrile compound represented by the formula (I) wherein R1 is a hydrogen atom, an alkyl group and the like, R2, R3, and R4 are the same or different and each is a hydrogen atom, an alkyl group and the like, R5 and R6 are the same or different and each is a hydrogen atom, a halogen atom and the like, m is 0 or 1, R is a halogen atom, a cyano group, a nitro group, a phenyl group optionally substituted by an alkyl group and the like, an alkyl group and the like, Ar1 is a phenyl group, a naphthyl group, a pyridyl group, a pyrazolyl group, or the like, each of which is optionally substituted by a halogen atom, a cyano group, a nitro group, alkyl group and the like, and W is —O—, —S—, —SO2—, or —N(R7)— wherein R7 is a hydrogen atom, a (C1-C6)alkyl group and the like, or a pharmacologically acceptable salt thereof.Type: ApplicationFiled: September 12, 2014Publication date: July 28, 2016Applicants: NIHON NOHYAKU CO., LTD., PITNEY PHARMACEUTICALS PTY LIMITEDInventors: Nobuharu ANDOH, Osamu SANPEI, Tetsuo TOGA, David Lawson MORRIS, Roger ASTON, Koji TANAKA, Tomokazu HINO
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Patent number: 8444282Abstract: A display device capable of expressing a particularly superior red color, for example, a red color of the sRGB standard, is provided. A display device 1 is composed of a red fluorescent body in which the red chromaticity point (xR, yR) satisfies xR?20.640 and yR?0.330, and a green fluorescent body.Type: GrantFiled: November 7, 2007Date of Patent: May 21, 2013Assignee: Sony CorporationInventors: Takahiro Igarashi, Tsuneo Kusunoki, Takashi Tamura, Tomokazu Hino
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Patent number: 8137584Abstract: Disclosed is a luminescent composition containing a fluorescent body having Eu2+ as a luminescent center. The luminescent composition is obtained by a process including the steps of mixing a raw material of the fluorescent body with an organic compound having elements other than oxygen, and sintering the mixture to form the fluorescent body from the raw material.Type: GrantFiled: October 29, 2007Date of Patent: March 20, 2012Assignee: Sony CorporationInventors: Takashi Tamura, Tomokazu Hino, Tsuneo Kusunoki, Takahiro Igarashi
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Patent number: 8048825Abstract: A haloalkylsulfonanilide derivative represented by general formula (I) or a salt thereof wherein R1 represents a halo(C1-C8)alkyl group, R2, R3, R4, R5, R6, R7, R8, R9 and R10 represent hydrogen atoms, etc., n represents 1 or 2, A represents an oxygen atom, W represents an oxygen atom, X represents a halogen atom and m represents an integer of 0 to 4, are compounds useful as herbicides having both of remarkable herbicidal effect and characteristics such as excellent crop-weed selectivity.Type: GrantFiled: November 16, 2007Date of Patent: November 1, 2011Assignee: Nihon Nohyaku Co., Ltd.Inventors: Tomokazu Hino, Yasuko Yamada, Toshihiko Shigenari, Koki Mametsuka
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Publication number: 20100308711Abstract: The present invention is to provide a luminescent composition, a light source device, and a display device each having a phosphor for which both avoidance of the shift of the luminescence wavelength band toward the shorter wavelength side and suppression of color unevenness are achieved. A configuration is provided in which a luminescent composition having a phosphor with the same crystal structure as that of CaAlSiN3 contains carbon at a ratio of at least 0.05 weight % or higher.Type: ApplicationFiled: July 30, 2007Publication date: December 9, 2010Applicant: SONY CORPORATIONInventors: Takashi Tamura, Tomokazu Hino, Tsuneo Kusunoki, Takahiro Igarashi
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Publication number: 20100016164Abstract: A haloalkylsulfonanilide derivative represented by general formula (I) or a salt thereof wherein R1 represents a halo(C1-C8)alkyl group, R2, R3, R4, R5, R6, R7, R8, R9 and R10 represent hydrogen atoms, etc., n represents 1 or 2, A represents an oxygen atom, W represents an oxygen atom, X represents a halogen atom and m represents an integer of 0 to 4, are compounds useful as herbicides having both of remarkable herbicidal effect and characteristics such as excellent crop-weed selectivity.Type: ApplicationFiled: November 16, 2007Publication date: January 21, 2010Inventors: Tomokazu Hino, Yasuko Yamada, Toshihiko Shigenari, Koki Mametsuka
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Publication number: 20100002413Abstract: A display device capable of expressing a particularly superior red color, for example, a red color of the sRGB standard, is provided. A display device 1 is composed of a red fluorescent body in which the red chromaticity point (xR, yR) satisfies xR?20.640 and yR?0.330, and a green fluorescent body.Type: ApplicationFiled: November 7, 2007Publication date: January 7, 2010Applicant: Sony CorporationInventors: Takahiro Igarashi, Tsuneo Kusunoki, Takashi Tamura, Tomokazu Hino
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Publication number: 20080274892Abstract: A haloalkylsulfonanilide derivative represented by the formula (I): {wherein R1 represents haloalkyl; R2 represents H, alkylcarbonyl, optionally substituted phenylcarbonyl, alkoxycarbonyl, optionally substituted phenoxycarbonyl, optionally substituted phenylsulfonyl, etc.; R3 and R4 each represents H, alkyl, cycloalkyl, halogeno, CN, etc.; R5, R6, R7, and R8 each represents H, halogeno, alkyl, cycloalkyl, optionally substituted phenyl(C1-6 alkyl), an optionally substituted heterocycle, etc.; A and W each represents O or S; and X represents one to four substituents selected among H, halogeno, alkyl, alkenyl, optionally substituted phenyl, optionally substituted phenylalkylaminocarbonyl, OH, CN, etc.} and a salt thereof; and a herbicide containing any of these compounds as an active ingredient. The herbicide is excellent in wide applicability, persistency, and selectivity for crops and effectiveness against weeds. It is excellent especially as a herbicide for rice fields.Type: ApplicationFiled: February 23, 2006Publication date: November 6, 2008Inventors: Tomokazu Hino, Toshihiko Shigenari, Takahiro Kiyokawa, Koki Mametsuka, Yasuko Yamada
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Publication number: 20080258112Abstract: Disclosed is a luminescent composition containing a fluorescent body having Eu2+as a luminescent center. The luminescent composition is obtained by a process including the steps of mixing a raw material of the fluorescent body with an organic compound having elements other than oxygen, and sintering the mixture to form the fluorescent body from the raw material.Type: ApplicationFiled: October 29, 2007Publication date: October 23, 2008Applicant: SONY CORPORATIONInventors: Takashi Tamura, Tomokazu Hino, Tsuneo Kusunoki, Takahiro Igarashi
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Patent number: 7057067Abstract: The present invention provides a process for producing 2-halobenzoic acids of the general formula (I), characterized by reacting a benzoic acid of formula (II) with a halogenating agent in the presence of Pd catalyst: (wherein A is —OH, —OM (M is alkali metal), —N(R6)R7 (R6 and R7 are each H, C1–C6 alkyl, optionally substituted phenyl, or the like); R is H, C1–C6 alkyl, C1–C6 alkylcarbonyl, carboxyl, C1–C12 alkoxycarbonyl, optionally substituted phenylcarbonyl, or the like; n is 0 to 4; X is Cl, Br or I, or alternatively (R)n may be present on benzene-constituting carbon atoms adjacent to each other and form a C3–C4 alkylene- or C3–C4 alkenylene-fused ring).Type: GrantFiled: April 27, 2001Date of Patent: June 6, 2006Assignee: Nihon Nohyaku Co., Ltd.Inventors: Hiroki Kodama, Takeshi Katsuhira, Tateki Nishida, Tomokazu Hino, Kenji Tsubata
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Publication number: 20030181759Abstract: The present invention provides a process for producing 2-halobenzoic acids of the general formula (I), characterized by reacting a benzoic acid of formula (II) with a halogenating agent in the presence of Pd catalyst: 1Type: ApplicationFiled: May 29, 2003Publication date: September 25, 2003Inventors: Hiroki Kodama, Takeshi Katsuhira, Tateki Nishida, Tomokazu Hino, Kenji Tsubata
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Patent number: 5358965Abstract: The present invention relates to a hydrazone derivative represented by the general formula (I) shown below: ##STR1## wherein the substituents are as defined in the specification, processes for preparing the derivative, and uses of the derivative as an insecticide.The hydrazone derivative has a marked insecticidal effect on insect pests, especially against LEPIDOPTERA and COLEOPTERA.Type: GrantFiled: May 28, 1993Date of Patent: October 25, 1994Assignee: Nihon Nohyaku Co., Ltd.Inventors: Tomokazu Hino, Nobuharu Andoh, Hiroshi Hamaguchi, Atsushi Kanaoka
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Patent number: 5304573Abstract: The present invention relates to a hydrazone derivative represented by the general formula (I) shown below: ##STR1## wherein the substituents are as defined in the specification, processes for preparing the derivative, and uses of the derivative as an insecticide.The hydrazone derivative has a marked insecticidal effect on insect pests, especially against LEPIDOPTERA and COLEOPTERA.Type: GrantFiled: November 13, 1991Date of Patent: April 19, 1994Assignee: Nihon Nohyaku Co., Ltd.Inventors: Tomokazu Hino, Nobuharu Andoh, Hiroshi Hamaguchi, Atsushi Kanaoka