Patents by Inventor Tomokazu Ozaki

Tomokazu Ozaki has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compounds exhibiting thrombopoietin-like activities
    Patent number: 6887890
    Abstract: The compounds of the invention are compounds represented by the following general formula (1): wherein E represents one selected from the group consisting of a methylidyne group and a nitrilo group, R1 represents one selected from the group consisting of optionally substituted aryl groups and optionally substituted heteroaryl groups, R2 represents one selected from the group consisting of a hydrogen atom and alkyl groups, W1 represents an amino acid residue, A represents one selected from the group consisting of a carbonyl group and a sulfonyl group, X1 represents one selected from the group consisting of optionally substituted alkylene groups and optionally substituted alkenylene groups, and p represents 0 or 1; and their pharmacologically acceptable salts, which exhibit thrombopoietin-like activity.
    Type: Grant
    Filed: May 30, 2001
    Date of Patent: May 3, 2005
    Assignee: Chugai Seiyaku Kabushiki Kaisha
    Inventors: Shinya Fujiwara, Tomokazu Ozaki, Toshiro Kozono, Kunihiro Hattori, Toru Esaki
  • Compounds exhibiting thrombopoietin-like activities
    Publication number: 20030162724
    Abstract: The compounds of the invention are compounds represented by the following general formula (1): 1
    Type: Application
    Filed: November 27, 2002
    Publication date: August 28, 2003
    Inventors: Shinya Fujiwara, Tomokazu Ozaki, Toshiro Kozono, Kunihiro Hattori, Toru Esaki
  • Crystalline fumarate of 2-phenyl-1, 3-thiazolidine-4-on derivative
    Patent number: 6191281
    Abstract: Disclosed are crystals of a compound represented by the formula: and processes for preparing them.
    Type: Grant
    Filed: July 27, 1999
    Date of Patent: February 20, 2001
    Assignee: Chugai Seiyaku Kabushiki Kaisha
    Inventors: Kazuya Nakagomi, Tatsuya Kato, Tomokazu Ozaki, Yoshikazu Kumagai
  • Benzene derivatives, compositions and methods for treating ischemic diseases
    Patent number: 5998452
    Abstract: The present invention is directed to a compound represented by formula (I): wherein, for example, R.sub.1, R.sub.2, R.sub.3, and R.sub.4 each represents a hydrogen atom; R.sub.6 and R.sub.7 each represent a substituted or unsubstituted lower alkyl group; A represents a group represented by formula (II): ##STR1## wherein R.sub.5 represents, for example, a hydrogen atom; and n represents an integer of 2 to 6, or a stereoisomer or optical isomer thereof and a pharmaceutically acceptable salt thereof and compositions and methods for treating ischemic diseases. The compounds represented by formula (I) have an inhibitory action on calcium overload in addition to a vasorelaxing activity (calcium antagonism) and an inhibitory action on lipid peroxidation and are useful as a preventive or treating agent for ischemic diseases and hypertension.
    Type: Grant
    Filed: October 7, 1997
    Date of Patent: December 7, 1999
    Assignee: Chugai Seiyaku Kabushiki Kaisha
    Inventors: Nobuhiro Ohi, Tatsuya Kato, Tomokazu Ozaki, Kazuhiko Tamura, Yoshiyuki Suzuki, Michitaka Akima