Patents by Inventor Tomokazu Takase

Tomokazu Takase has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20110229980
    Abstract: The present teaching provides a fluorescent oligonucleotide probe having a high degree of design flexibility and wide applicability, as well as the use thereof. This is an oligonucleotide probe capable of forming a stem and loop, comprising at least one fluorophore located between adjacent nucleotides in the stem and is linked to a unit represented by Formula (1) and at least one quencher located at a site capable of pairing up with the at least one fluorophore located between the adjacent nucleotides in the stem and is linked to a unit represented by Formula (2). (In the formulae, X represents the fluorophore, Y represents the quencher, R1 represents an optionally substituted C2 or C3 alkylene chain, R2 represents an optionally substituted C0-2 alkylene chain, and Z represents a direct bond or linker.
    Type: Application
    Filed: December 31, 2010
    Publication date: September 22, 2011
    Applicants: National University Corporation Nagoya University, NGK Insulators, Ltd.
    Inventors: Hiroyuki ASANUMA, Xingguo Liang, Hiromu Kashida, Yasuko Yoshida, Tomokazu Takase, Kousuke Niwa
  • Publication number: 20110046015
    Abstract: Disclosed is a peptide immobilization technique which can achieve the immobilization of a satisfactory quantity of a peptide on a solid support. In the immobilization of a peptide on a solid support, a surfactant is allowed to coexist on the solid support together with the peptide. In this manner, the quantity of the peptide immobilized on the solid support can be increased.
    Type: Application
    Filed: January 29, 2009
    Publication date: February 24, 2011
    Inventors: Hiroyuki Honda, Tsutomu Kawabe, Mina Okochi, Miyoko Matsushima, Naoki Matsumoto, Mitsuo Kawase, Yasuko Yoshida, Tomokazu Takase
  • Publication number: 20090042734
    Abstract: An object of the present invention is to provide a probe array having partitioned array regions with uniform surface chemical properties. The probe array of the present invention includes a substrate having a plurality of partitioned array regions where many probes are immobilized and a separator attached to the substrate and including partitions partitioning the array regions. The above object can be achieved by attaching the separator including the partitions capable of partitioning instead of forming hydrophobic regions on a surface of the substrate by printing or chemical treatment.
    Type: Application
    Filed: March 27, 2006
    Publication date: February 12, 2009
    Applicant: NGK INSULATORS, LTD.
    Inventors: Yasuko Yoshida, Kazunari Yamada, Tomokazu Takase, Akinobu Oribe
  • Publication number: 20070238870
    Abstract: The hybridization device of the invention aims to attain a hybridization reaction of high reproducibility. A hybridization device 2 for a hybridization reaction of nucleic acid has a cover member 10 that defines a cavity 12, which includes a nucleic acid fixation area 6 of a substrate 4 for fixation of a nucleic acid probe and has capacity for storage of a liquid for the hybridization reaction therein. At least part of an area exposed to inside of the cavity 12 forms a hydrophobic region 18. Adequate control of the surface characteristic of the area exposed to the cavity for implementing the hybridization reaction desirably enhances the signal intensity and reduces a variation in signal intensity, thus attaining the hybridization reaction of high reproducibility.
    Type: Application
    Filed: July 29, 2005
    Publication date: October 11, 2007
    Applicant: NGK Insulators, Ltd.
    Inventors: Mitsuo Kawase, Yasuko Yoshida, Kazunari Yamada, Tomokazu Takase