Patents by Inventor Tomoko Fujishima

Tomoko Fujishima has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 7148011
    Abstract: The differential display method was used to search for a gene whose expression level in eosinophils collected from patients with atopic dermatitis differs in the exacerbation stage and in the remission stage. As a result, gene “2090-05” showing a significant increase in expression in eosinophils of patients in the remission stage was isolated. This gene is usable in testing for an allergic disease and screening for a candidate compound for a therapeutic agent therefor an allergic disease.
    Type: Grant
    Filed: September 21, 2001
    Date of Patent: December 12, 2006
    Assignees: Japan as represented by General Director of Agency of National Center for Child Health and Development, Eisai Co., Ltd., Genox Research, Inc.
    Inventors: Yuji Sugita, Ryoichi Hashida, Kaoru Ogawa, Tomoko Fujishima, Takeshi Nagasu, Gozoh Tsujimoto, Eiki Takahashi
  • Patent number: 6986990
    Abstract: T cells from multiple subjects who showed different cedar pollen specific IgE titers were prepared before and after cedar pollen dispersal, and differential display analysis was performed to screen for pollen antigen responsive genes. As a result, a novel gene was successfully isolated whose expression is significantly higher in subjects with high cedar pollen specific IgE titer. The inventors have found that it is possible to use this gene to test for an allergic disease and to screen for candidate compounds for therapeutic drugs for an allergic disease.
    Type: Grant
    Filed: April 26, 2000
    Date of Patent: January 17, 2006
    Assignee: Genox Research, Inc.
    Inventors: Takeshi Nagasu, Yuji Sugita, Tomoko Fujishima, Tadahiro Oshida, Masaya Obayashi, Shigemichi Gunji, Izumi Obayashi, Yukiho Imai, Nei Yoshida, Kaoru Ogawa, Keiko Matsui
  • Publication number: 20040038252
    Abstract: The differential display method was used to search for a gene whose expression level in eosinophils collected from patients with atopic dermatitis differs in the exacerbation stage and in the remission stage. As a result, gene “2090-05” showing a significant increase in expression in eosinophils of patients in the remission stage was isolated. This gene is usable in testing for an allergic disease and screening for a candidate compound for a therapeutic agent therefor an allergic disease.
    Type: Application
    Filed: July 31, 2003
    Publication date: February 26, 2004
    Inventors: Yuji Sugita, Ryoichi Hashida, Kaoru Ogawa, Tomoko Fujishima, Takeshi Nagasu, Gozoh Tsujimoto, Eiki Takahashi
  • Publication number: 20040023263
    Abstract: The differential display method was used to search for a gene whose expression level in eosinophils collected from patients with atopic dermatitis differs in the exacerbation stage and in the remission stage. As a result, genes “2259-01”, “2298-09”, “2255-02”, “2292-04”, and “2182-02” showing a significant increase in expression in eosinophils of patients in the remission stage was isolated. These genes are usable in testing for an allergic disease and screening for a candidate compound for a therapeutic agent therefor an allergic disease.
    Type: Application
    Filed: August 6, 2003
    Publication date: February 5, 2004
    Inventors: Yuji Sugita, Ryoichi Hashida, Kaoru Ogawa, Tomoko Fujishima, Takeshi Nagasu, Hirohisa Saito