Patents by Inventor Tomoko Hashimoto
Tomoko Hashimoto has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20250009848Abstract: The purpose of the present invention is to provide an agent for improving intrauterine bacterial flora, and a method for determining whether intrauterine bacterial flora has been improved or normalized. An aspect of the present invention is an agent for improving intrauterine bacterial flora that contains lactoferrin or a salt thereof as an active ingredient. Additionally provided are: an agent or composition for improving intrauterine flora or treating or preventing diseases caused by the imbalance of intrauterine bacterial flora, the agent or composition containing lactoferrin or a salt thereof; a method for treating or preventing diseases caused by imbalance of intrauterine bacterial flora, the method comprising administrating the agent or composition; and a method for determining whether intrauterine bacterial flora has been improved or normalized.Type: ApplicationFiled: September 25, 2024Publication date: January 9, 2025Applicant: NRL Pharma, Inc.Inventors: Tatsuo Hoshino, Yoshiyuki Sakuraba, Yoko Nagai, Koichi Kyono, Tomoko Hashimoto
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Publication number: 20220040270Abstract: The purpose of the present invention is to provide an agent for improving intrauterine bacterial flora, and a method for determining whether intrauterine bacterial flora has been improved or normalized. An aspect of the present invention is an agent for improving intrauterine bacterial flora that contains lactoferrin or a salt thereof as an active ingredient. Additionally provided are: an agent or composition for improving intrauterine flora or treating or preventing diseases caused by the imbalance of intrauterine bacterial flora, the agent or composition containing lactoferrin or a salt thereof; a method for treating or preventing diseases caused by imbalance of intrauterine bacterial flora, the method comprising administrating the agent or composition; and a method for determining whether intrauterine bacterial flora has been improved or normalized.Type: ApplicationFiled: September 11, 2019Publication date: February 10, 2022Applicants: NRL Pharma, Inc., Varinos, INC.Inventors: Tatsuo Hoshino, Yoshiyuki Sakuraba, Yoko Nagai, Koichi Kyono, Tomoko Hashimoto
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Patent number: 9668658Abstract: A first calculation unit receives phase characteristics Pa(f) and Pb(f) outputted from frequency transform units, calculates a propagation time difference based on a phase difference between the two phase characteristics in a high-frequency component thereof, and calculates a pulse wave velocity by dividing a difference in the distances of vascular pathways from the heart to respective measurement areas. Meanwhile, a second calculation unit calculates a pulse wave velocity by dividing the stated difference in the distances by a appearance time difference at a predetermined position in respective pulse waveforms obtained by rendering the measurement signals Pa(t) and Pb(t) on a time axis. A comparison unit compares the pulse wave velocities, and in the case where the ratio thereof is outside a predetermined range, an evaluation result indicating that it is possible that a predetermined pathologic change is present in the vascular pathway is outputted to a display processing unit.Type: GrantFiled: December 18, 2012Date of Patent: June 6, 2017Assignee: OMRON HEALTHCARE CO., LTD.Inventors: Hironori Sato, Naoki Mori, Tomoko Hashimoto, Toshihiko Ogura, Shozo Takamatsu, Hideo Utsuno, Kimihiko Kichikawa, Hirofumi Ito
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Patent number: 8596976Abstract: The amount of cooling air (cooling medium) can be reduced, and low-temperature cooling air is prevented from being blown out through film cooling holes. Part of a cooling medium impingement-cooling an inner circumferential surface of a blade main body located on a ventral side further impingement-cools the inner circumferential surface of the blade main body located on a dorsal side and is blown out through film cooling holes in the blade main body that are located on the dorsal side.Type: GrantFiled: November 7, 2008Date of Patent: December 3, 2013Assignee: Mitsubishi Heavy Industries, Ltd.Inventors: Satoshi Hada, Tomoko Hashimoto, Masanori Yuri, Masamitsu Kuwabara
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Patent number: 8366391Abstract: Provided is a turbine blade structure that is capable of suppressing quality variations of cast products during the manufacturing of turbine blades. A turbine blade structure wherein the space inside an air foil is divided into a plurality of cavities, partitioned by rib members provided substantially perpendicular to the center line connecting a leading edge and a trailing edge, is provided with partition members that partition the inside of the cavities located in the central portion of the blade, excluding the blade leading-edge side and the blade trailing-edge side, into blade pressure side cavities and blade suction side cavities substantially along the center line, wherein blade leading-edge end portions and blade trailing-edge end portions of the partition members are inserted from one shroud surface side to the other shroud surface side along engagement grooves formed on the rib members.Type: GrantFiled: April 23, 2009Date of Patent: February 5, 2013Assignee: Mitsubishi Heavy Industries, Ltd.Inventors: Keizo Tsukagoshi, Tomoko Hashimoto, Satoshi Hada
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Patent number: 8079815Abstract: In a turbine blade in which a tabular rib partitioning the blade into a pressure side and a suction side is provided in substantially the midsection of the blade along a center line connecting a leading edge and a trailing edge, and at least two cavities of which a cavity at the suction side and a cavity at the pressure side do not communicate with each other are provided, a pressure adjustment member for cooling air flowing into and out of the cavity at the suction side reduces the amount of cooling air flowing into the suction side, relative to the pressure side.Type: GrantFiled: December 9, 2009Date of Patent: December 20, 2011Assignee: Mitsubishi Heavy Industries, Ltd.Inventors: Satoshi Hada, Tomoko Hashimoto, Masanori Yuri, Keizo Tsukagoshi
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Publication number: 20110142597Abstract: Provided is a turbine blade structure that is capable of suppressing quality variations of cast products during the manufacturing of turbine blades. A turbine blade structure wherein the space inside an air foil is divided into a plurality of cavities, partitioned by rib members provided substantially perpendicular to the center line connecting a leading edge and a trailing edge, is provided with partition members that partition the inside of the cavities located in the central portion of the blade, excluding the blade leading-edge side and the blade trailing-edge side, into blade pressure side cavities and blade suction side cavities substantially along the center line, wherein blade leading-edge end portions and blade trailing-edge end portions of the partition members are inserted from one shroud surface side to the other shroud surface side along engagement grooves formed on the rib members.Type: ApplicationFiled: April 23, 2009Publication date: June 16, 2011Applicant: MITSUBISHI HEAVY INDUSTRIES, LTD.Inventors: Keizo Tsukagoshi, Tomoko Hashimoto, Satoshi Hada
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Publication number: 20110103971Abstract: The amount of cooling air (cooling medium) can be reduced, and low-temperature cooling air is prevented from being blown out through film cooling holes. Part of a cooling medium impingement-cooling an inner circumferential surface of a blade main body located on a ventral side further impingement-cools the inner circumferential surface of the blade main body located on a dorsal side and is blown out through film cooling holes in the blade main body that are located on the dorsal side.Type: ApplicationFiled: November 7, 2008Publication date: May 5, 2011Applicant: MITSUBISHI HEAVY INDUSTRIES, LTD.Inventors: Satoshi Hada, Tomoko Hashimoto, Masanori Yuri, Masamitsu Kuwabara
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Publication number: 20100150734Abstract: In a turbine blade in which a tabular rib partitioning the blade into a pressure side and a suction side is provided in substantially the midsection of the blade along a center line connecting a leading edge and a trailing edge, and at least two cavities of which a cavity at the suction side and a cavity at the pressure side do not communicate with each other are provided, a pressure adjustment member for cooling air flowing into and out of the cavity at the suction side reduces the amount of cooling air flowing into the suction side, relative to the pressure side.Type: ApplicationFiled: December 9, 2009Publication date: June 17, 2010Applicant: MITSUBISHI HEAVY INDUSTRIES, LTD.Inventors: Satoshi Hada, Tomoko Hashimoto, Masanori Yuri, Keizo Tsukagoshi