Abstract: A peptide Met-Lys-Pro, which is obtained by chemical synthesis ot hydrolysis of casein, is used as the active ingredient of angiotensin converting enzyme inhibitors or hypotensive drugs.

Abstract: A peptide Met-Lys-Pro, which is obtained by chemical synthesis ot hydrolysis of casein, is used as the active ingredient of angiotensin converting enzyme inhibitors or hypotensive drugs.

Abstract: The lay out method of a semiconductor integrated circuit according to the present invention which performs wiring between circuit blocks using the arrangement of a plurality of circuit blocks constituting a semiconductor integrated circuit and a wiring consisting of a plurality of wiring layers has an arrangement step for arranging circuit blocks, a wiring barrier region setting step which makes a wiring barrier region to be wiring enabled for a specific wiring layer out of a plurality of wiring layers by setting to surround at least one circuit block in a ring form out of a plurality of circuit blocks, a wiring step for generating a wiring which connects the terminal of a circuit block with the terminal of another circuit block, and an antenna ratio decision step in which whether or not the antenna ratio, defined by the quotient obtained by dividing the side-face area of a wiring for each layer connected to a terminal by the gate area of transistors constituting a circuit block connected to the terminal, is