Patents by Inventor Tomoko Kamei

Tomoko Kamei has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Reagent for measuring creatine kinase activity and measuring method thereof
    Patent number: 5968756
    Abstract: The present invention provides such a measuring method of the CK isoform and a reagent therefor. Accordingly, the present invention provides a reagent for measuring creatine kinase (CK) activity comprising an antibody, wherein said antibody inhibits CK-M.sub.T subunit, but does not inhibit CK-M.sub.S subunit.The present invention also provides a method for measuring CK activity comprising determining an inhibition of CK of body fluids using a reagent for measuring CK activity, wherein said reagent comprises an antibody which inhibits CK-M.sub.T subunit, but does not inhibit CK-M.sub.S subunit.
    Type: Grant
    Filed: August 22, 1997
    Date of Patent: October 19, 1999
    Assignees: Unitika Ltd., Iatron Laboratories, Inc.
    Inventors: Tadao Suzuki, Tomoko Kamei, Mihoko Era, Hiroyuki Tsubota
  • Reagent for measuring creatine kinase activity and measuring method thereof
    Patent number: 5804394
    Abstract: The present invention provides such a measuring method of the CK isoform and a reagent therefor. Accordingly, the present invention provides a reagent for measuring creatine kinase (CK) activity comprising an antibody, wherein said antibody inhibits CK-M.sub.T subunit, but does not inhibit CK-M.sub.S subunit.The present invention also provides a method for measuring CK activity comprising determining an inhibition of CK of body fluids using a reagent for measuring CK activity, wherein said reagent comprises an antibody which inhibits CK-M.sub.T subunit, but does not inhibit CK-M.sub.S subunit.
    Type: Grant
    Filed: October 20, 1993
    Date of Patent: September 8, 1998
    Assignees: Unitika Ltd., Iatron Laboratories, Inc.
    Inventors: Tadao Suzuki, Tomoko Kamei, Mihoko Era, Hiroyuki Tsubota
  • Reagent for determining triglycerides comprising a thermostable lipoprotein lipase from streptomyces
    Patent number: 5244798
    Abstract: A reagent composition for determining blood triglycerides comprising a color former and a thermostable lipoprotein lipase obtained from Streptomyces 7825 (FERM P-9983, FERM BP-2489) is presented.
    Type: Grant
    Filed: August 17, 1992
    Date of Patent: September 14, 1993
    Assignee: Unitika Ltd.
    Inventors: Akira Takeda, Tomoko Kamei, Masao Kageyama, Kenzo Motosugi
  • Method for producing a thermostable lipoprotein lipase from streptomyces
    Patent number: 5232846
    Abstract: The present invention is directed toward a thermostable lipoprotein lipase capable of hydrolyzing triglycerides in lipoproteins to glycerol and fatty acids, a process for producing the thermostable lipoprotein lipase, and a blood triglyceride determining reagent containing the thermostable lipoprotein lipase. The thermostable lipoprotein lipase exhibits about 100% retention of the hydrolyzing activity when treated in a buffer having a pH of from bout 4 to 7 at about 60.degree. C. for about 15 minutes and a glycerol forming activity/fatty acid forming activity ratio of at least about 15%. The process comprises cultivating a thermophilic actinomycetes, particularly Streptomyces 7825 (FERM P-9983, FERM BP-2489 is cultivated to produce a thermostable lipoprotein lipase.
    Type: Grant
    Filed: September 3, 1992
    Date of Patent: August 3, 1993
    Assignee: Unitika Ltd.
    Inventors: Akira Takeda, Tomoko Kamei, Masao Kageyama, Kenzo Motosugi
  • Thermostable lipoprotein lipase, process for producing the same, and triglyceride determining reagent using the same
    Patent number: 5173417
    Abstract: The present invention is directed toward a thermostable lipoprotein lipase capable of hydrolyzing triglycerides in lipoproteins to glycerol and fatty acids, a process for producing the thermostable lipoprotein lipase, and a blood triglyceride determining reagent containing the thermostable lipoprotein lipase. The thermostable lipoprotein lipase exhibits about 100% retention of the hydrolyzing activity when treated in a buffer having a pH of from about 4 to 7 at about 60.degree. C. for about 15 minutes and a glycerol forming activity/fatty acid forming activity ratio of at least about 15%. The process comprises cultivating a thermophilic actinomycetes, particularly Streptomyces 7825 (FERM P-9983, FERM BP-2489 and recovering lipoprotein lipase from the culture.
    Type: Grant
    Filed: August 9, 1989
    Date of Patent: December 22, 1992
    Assignee: Unitika Ltd.
    Inventors: Akira Takeda, Tomoko Kamei, Masao Kageyama, Kenzo Motosugi
  • Acyl-CoA synthetase
    Patent number: 4794084
    Abstract: An acyl-CoA synthetase is disclosed having the following characteristics:(a) Reaction:Capable of acting on saturated or unsaturated lower to higher fatty acids to produce a CoA derivative thereof (Acyl-CoA), adenosine monophosphate and pyrophosporic acid, in the presence of adenosine triphosphate and coenzyme A;(b) Stability:Having a residual activity of not less than about 50% after being incubated in a buffer (pH about 7.5 for about 15 minutes at a temperature of about 55.degree. C.; and(c) Optimum reaction temperature:Having an optimum reaction temperature in the range of from 50.degree. to 60.degree. C.Also disclosed is Psuedomonas UKSW-3733 strain which is capable of producing the acyl-CoA synthetase, which has an optimum temperature for growth in the range of from 45.degree. to 55.degree. C. and is incapable of assimilating carbonates.
    Type: Grant
    Filed: February 5, 1987
    Date of Patent: December 27, 1988
    Assignee: Unitika Ltd.
    Inventors: Mitsuo Watanabe, Hiromi Sato, Tomoko Kamei, Masao Kageyama