Patents by Inventor Tomoko Kobayashi
Tomoko Kobayashi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
-
Patent number: 11966550Abstract: A sensor module includes a sensor that includes a first sensor layer of a capacitance type including a plurality of first detection units arranged two-dimensionally and a second sensor layer of a capacitance type including a plurality of second detection units arranged two-dimensionally, the first sensor layer being provided on the second sensor layer, and a control unit that scans the plurality of first detection units and the plurality of second detection units.Type: GrantFiled: January 29, 2021Date of Patent: April 23, 2024Assignee: Sony Group CorporationInventors: Tetsuro Goto, Ken Kobayashi, Kei Tsukamoto, Tomoko Katsuhara
-
Publication number: 20240094099Abstract: The methods for sample preparation disclosed herein utilize an air phase to reduce aqueous phase associated with magnetic particles bound to nucleic acids to decrease carryover of one or more contaminants, such as, cell debris, chaotropic agents, non-specifically attached molecules, and the like. This air-transfer step is improved by using a combination of a first population of magnetic particles and a second population of magnetic particles, where the first population of magnetic particles is capable of associating with nucleic acids, and the magnetic particles in the second population are at least two-times larger in size than the size of the magnetic particles in the first population. As discussed herein, the use of this second population of magnetic particles improves the transfer of the first population of magnetic particles by reducing loss of the first magnetic particles during the transfer. The sample preparation methods may be semi-automated or completely automated.Type: ApplicationFiled: January 28, 2022Publication date: March 21, 2024Inventors: Austin M. Derfus, Karthikeyan Kumaravadivelu, Kai Yang, Adrian P. Crute, Darren S. Gray, Armando R. Tovar, Tomoko Kobayashi, Tomotaka Komori, Yoshiko Wada, Masato Orikasa, Toru Yoshimura
-
Patent number: 10809511Abstract: The total internal reflection microscope has an illumination optical system that relays light from a light source with a relay optical system, forms an image of the light source on the incident pupil plane of the objective lens and irradiates a sample with the illumination light via an objective lens, has an angle adjustment mirror for changing the position of the image of the light source in a direction orthogonal to the optical axis, an optical detector for detecting the intensity of the returning illumination light reflected by the sample and collected by the objective lens, and a controller for determining the operation amount of the angle adjustment mirror, wherein the controller determines the operation amount of the angle adjustment mirror so that the illumination light is totally reflected at the sample based on the change in intensity of the returning light when the angle adjustment mirror is changed.Type: GrantFiled: February 21, 2019Date of Patent: October 20, 2020Assignee: NIKON CORPORATIONInventors: Takayuki Morita, Akitoshi Suzuki, Tomoko Kobayashi, Keita Masuda
-
Patent number: 10654605Abstract: A packing apparatus includes a sealing mechanism, a timing sensing section, and a control section. The sealing mechanism affixes tape continuously on portions of a cardboard box transported with major flaps thereof folded. The sealing mechanism includes an affixing roller to press the tape against a first side surface and the major flaps. The timing sensing section senses the timing at which the affixing of the tape on the first side surface is initiated. The control section controls pressing force exerted by the affixing roller, based on a result of the sensing performed by the timing sensing section, in such a way that the pressing force is reduced after the affixing of the tape on the first side surface is initiated.Type: GrantFiled: October 14, 2015Date of Patent: May 19, 2020Assignee: ISHIDA CO., LTD.Inventors: Atsushi Takahashi, Yuji Yokota, Yoshinobu Shimomae, Tomoko Kobayashi
-
Publication number: 20190187449Abstract: The total internal reflection microscope has an illumination optical system that relays light from a light source with a relay optical system, forms an image of the light source on the incident pupil plane of the objective lens and irradiates a sample with the illumination light via an objective lens, has an angle adjustment mirror for changing the position of the image of the light source in a direction orthogonal to the optical axis, an optical detector for detecting the intensity of the returning illumination light reflected by the sample and collected by the objective lens, and a controller for determining the operation amount of the angle adjustment mirror, wherein the controller determines the operation amount of the angle adjustment mirror so that the illumination light is totally reflected at the sample based on the change in intensity of the returning light when the angle adjustment mirror is changed.Type: ApplicationFiled: February 21, 2019Publication date: June 20, 2019Applicant: NIKON CORPORATIONInventors: Takayuki MORITA, Akitoshi SUZUKI, Tomoko KOBAYASHI, Keita MASUDA
-
Patent number: 10241312Abstract: The total internal reflection microscope has an illumination optical system that relays light from a light source with a relay optical system, forms an image of the light source on the incident pupil plane of the objective lens and irradiates a sample with the illumination light via an objective lens, has an angle adjustment mirror for changing the position of the image of the light source in a direction orthogonal to the optical axis, an optical detector for detecting the intensity of the returning illumination light reflected by the sample and collected by the objective lens, and a controller for determining the operation amount of the angle adjustment mirror, wherein the controller determines the operation amount of the angle adjustment mirror so that the illumination light is totally reflected at the sample based on the change in intensity of the returning light when the angle adjustment mirror is changed.Type: GrantFiled: April 29, 2016Date of Patent: March 26, 2019Assignee: NIKON CORPORATIONInventors: Takayuki Morita, Akitoshi Suzuki, Tomoko Kobayashi, Keita Masuda
-
Publication number: 20180022492Abstract: A packing apparatus includes a sealing mechanism, a timing sensing section, and a control section. The sealing mechanism affixes tape continuously on portions of a cardboard box transported with major flaps thereof folded. The sealing mechanism includes an affixing roller to press the tape against a first side surface and the major flaps. The timing sensing section senses the timing at which the affixing of the tape on the first side surface is initiated. The control section controls pressing force exerted by the affixing roller, based on a result of the sensing performed by the timing sensing section, in such a way that the pressing force is reduced after the affixing of the tape on the first side surface is initiated.Type: ApplicationFiled: October 14, 2015Publication date: January 25, 2018Inventors: Atsushi TAKAHASHI, Yuji YOKOTA, Yoshinobu SHIMOMAE, Tomoko KOBAYASHI
-
Patent number: 9516209Abstract: An imaging apparatus includes an imaging unit for capturing a subject and generating image data of the subject, an operation input unit for receiving inputs of operation signals containing a release signal for instructing the imaging unit to shoot, an acceleration detector for detecting an acceleration of the imaging apparatus, a state detector for separately detecting a case in which the imaging apparatus is overland, a case in which the imaging apparatus is underwater and a photographer shoots while swimming, and a case in which the imaging apparatus is underwater and the photographer shoots while changing a water depth, and a control unit for performing operation control depending on an input into the operation input unit and/or into the acceleration detector according to a state detection result by the state detector.Type: GrantFiled: February 3, 2014Date of Patent: December 6, 2016Assignee: Olympus CorporationInventors: Yuko Watanabe, Yoko Saito, Tomoko Kobayashi, Koichi Shintani
-
Publication number: 20160246043Abstract: The total internal reflection microscope has an illumination optical system that relays light from a light source with a relay optical system, forms an image of the light source on the incident pupil plane of the objective lens and irradiates a sample with the illumination light via an objective lens, has an angle adjustment mirror for changing the position of the image of the light source in a direction orthogonal to the optical axis, an optical detector for detecting the intensity of the returning illumination light reflected by the sample and collected by the objective lens, and a controller for determining the operation amount of the angle adjustment mirror, wherein the controller determines the operation amount of the angle adjustment mirror so that the illumination light is totally reflected at the sample based on the change in intensity of the returning light when the angle adjustment mirror is changed.Type: ApplicationFiled: April 29, 2016Publication date: August 25, 2016Applicant: NIKON CORPORATIONInventors: Takayuki MORITA, Akitoshi SUZUKI, Tomoko KOBAYASHI, Keita MASUDA
-
Publication number: 20140210985Abstract: An imaging apparatus includes an imaging unit for capturing a subject and generating image data of the subject, an operation input unit for receiving inputs of operation signals containing a release signal for instructing the imaging unit to shoot, an acceleration detector for detecting an acceleration of the imaging apparatus, a state detector for separately detecting a case in which the imaging apparatus is overland, a case in which the imaging apparatus is underwater and a photographer shoots while swimming, and a case in which the imaging apparatus is underwater and the photographer shoots while changing a water depth, and a control unit for performing operation control depending on an input into the operation input unit and/or into the acceleration detector according to a state detection result by the state detector.Type: ApplicationFiled: February 3, 2014Publication date: July 31, 2014Applicant: Olympus Imaging Corp.Inventors: Yuko WATANABE, Yoko SAITO, Tomoko KOBAYASHI, Koichi SHINTANI
-
Patent number: 8643713Abstract: An imaging apparatus includes an imaging unit for capturing a subject and generating image data of the subject, an operation input unit for receiving inputs of operation signals containing a release signal for instructing the imaging unit to shoot, an acceleration detector for detecting an acceleration of the imaging apparatus, a state detector for separately detecting a case in which the imaging apparatus is overland, a case in which the imaging apparatus is underwater and a photographer shoots while swimming, and a case in which the imaging apparatus is underwater and the photographer shoots while changing a water depth, and a control unit for performing operation control depending on an input into the operation input unit and/or into the acceleration detector according to a state detection result by the state detector.Type: GrantFiled: August 9, 2013Date of Patent: February 4, 2014Assignee: Olympus Imaging Corp.Inventors: Yuko Watanabe, Yoko Saito, Tomoko Kobayashi, Koichi Shintani
-
Publication number: 20130321611Abstract: An imaging apparatus includes an imaging unit for capturing a subject and generating image data of the subject, an operation input unit for receiving inputs of operation signals containing a release signal for instructing the imaging unit to shoot, an acceleration detector for detecting an acceleration of the imaging apparatus, a state detector for separately detecting a case in which the imaging apparatus is overland, a case in which the imaging apparatus is underwater and a photographer shoots while swimming, and a case in which the imaging apparatus is underwater and the photographer shoots while changing a water depth, and a control unit for performing operation control depending on an input into the operation input unit and/or into the acceleration detector according to a state detection result by the state detector.Type: ApplicationFiled: August 9, 2013Publication date: December 5, 2013Applicant: Olympus Imaging Corp.Inventors: Yuko WATANABE, Yoko SAITO, Tomoko KOBAYASHI, Koichi SHINTANI
-
Patent number: 8531515Abstract: An imaging apparatus includes an imaging unit for capturing a subject and generating image data of the subject, an operation input unit for receiving inputs of operation signals containing a release signal for instructing the imaging unit to shoot, an acceleration detector for detecting an acceleration of the imaging apparatus, a state detector for separately detecting a case in which the imaging apparatus is overland, a case in which the imaging apparatus is underwater and a photographer shoots while swimming, and a case in which the imaging apparatus is underwater and the photographer shoots while changing a water depth, and a control unit for performing operation control depending on an input into the operation input unit and/or into the acceleration detector according to a state detection result by the state detector.Type: GrantFiled: September 27, 2010Date of Patent: September 10, 2013Assignee: Olympus Imaging Corp.Inventors: Yuko Watanabe, Yoko Saito, Tomoko Kobayashi, Koichi Shintani
-
Publication number: 20110074945Abstract: An imaging apparatus includes an imaging unit for capturing a subject and generating image data of the subject, an operation input unit for receiving inputs of operation signals containing a release signal for instructing the imaging unit to shoot, an acceleration detector for detecting an acceleration of the imaging apparatus, a state detector for separately detecting a case in which the imaging apparatus is overland, a case in which the imaging apparatus is underwater and a photographer shoots while swimming, and a case in which the imaging apparatus is underwater and the photographer shoots while changing a water depth, and a control unit for performing operation control depending on an input into the operation input unit and/or into the acceleration detector according to a state detection result by the state detector.Type: ApplicationFiled: September 27, 2010Publication date: March 31, 2011Inventors: Yuko Watanabe, Yoko Saito, Tomoko Kobayashi, Koichi Shintani
-
Patent number: 5800982Abstract: The present invention relates to an NS4-related antigenic peptide capable of reacting specifically with antibodies directed against Group I of hepatitis C virus (HCV); to an NS4-related antigenic peptide capable of reacting specifically with antibodies directed against Group II of HCV; to a kit for identifying HCV Groups I or II which comprises said peptides in separate sections; and to methods for grouping HCV. The peptides of the present invention can be used to detect HCV Groups I or II specifically as well as the detection of patients having the mixed infection, by which HCV Group II-infected patients can receive early interferon treatment effectively. The peptides are also useful for diagnosis of HCV infection.Type: GrantFiled: July 24, 1996Date of Patent: September 1, 1998Assignee: Tonen CorporationInventors: Akira Hasegawa, Noboru Maki, Shintaro Yagi, Tomiko Kashiwakuma, Kenjiro Yamaguchi, Naoko Ikeguchi, Tomoko Kobayashi, Chiaki Senoo
-
Patent number: 5762929Abstract: The present invention relates to an novel anti-motoneuron-disease agent, comprising superoxide dismutase conjugated with lecithin through chemical crosslinking represented in the following generic formula (PC-SOD) as an effective ingredient:SOD--?C(O)--(CH.sub.2).sub.n --C(O)--X!.sub.mwherein SOD represents superoxide dismutase and X represents a residue of lysolecithin having a hydroxy group at position 2 of glycerol whose hydrogen atom of the hydroxyl group at position 2 is removed.A pharmaceutical agent of the present invention may improve symptoms of motoneuron diseases such as amyotrophic lateral sclerosis etc. by oral or parenteral administration. The present invention also relates to a novel treatment method for motoneuron disease by administrating PC-SOD and novel use of PC-SOD as a medical composition for preparing an agent for treating motoneuron disease.Type: GrantFiled: July 31, 1995Date of Patent: June 9, 1998Assignee: SAM Research CorporationInventors: Masao Kinoshita, Yasuo Iwasaki, Ken Ikeda, Toshiya Shiojima, Nozomu Tagaya, Tomoko Kobayashi