Patents by Inventor Tomoko Kobayashi

Tomoko Kobayashi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11966550
    Abstract: A sensor module includes a sensor that includes a first sensor layer of a capacitance type including a plurality of first detection units arranged two-dimensionally and a second sensor layer of a capacitance type including a plurality of second detection units arranged two-dimensionally, the first sensor layer being provided on the second sensor layer, and a control unit that scans the plurality of first detection units and the plurality of second detection units.
    Type: Grant
    Filed: January 29, 2021
    Date of Patent: April 23, 2024
    Assignee: Sony Group Corporation
    Inventors: Tetsuro Goto, Ken Kobayashi, Kei Tsukamoto, Tomoko Katsuhara
  • Publication number: 20240094099
    Abstract: The methods for sample preparation disclosed herein utilize an air phase to reduce aqueous phase associated with magnetic particles bound to nucleic acids to decrease carryover of one or more contaminants, such as, cell debris, chaotropic agents, non-specifically attached molecules, and the like. This air-transfer step is improved by using a combination of a first population of magnetic particles and a second population of magnetic particles, where the first population of magnetic particles is capable of associating with nucleic acids, and the magnetic particles in the second population are at least two-times larger in size than the size of the magnetic particles in the first population. As discussed herein, the use of this second population of magnetic particles improves the transfer of the first population of magnetic particles by reducing loss of the first magnetic particles during the transfer. The sample preparation methods may be semi-automated or completely automated.
    Type: Application
    Filed: January 28, 2022
    Publication date: March 21, 2024
    Inventors: Austin M. Derfus, Karthikeyan Kumaravadivelu, Kai Yang, Adrian P. Crute, Darren S. Gray, Armando R. Tovar, Tomoko Kobayashi, Tomotaka Komori, Yoshiko Wada, Masato Orikasa, Toru Yoshimura
  • Patent number: 10809511
    Abstract: The total internal reflection microscope has an illumination optical system that relays light from a light source with a relay optical system, forms an image of the light source on the incident pupil plane of the objective lens and irradiates a sample with the illumination light via an objective lens, has an angle adjustment mirror for changing the position of the image of the light source in a direction orthogonal to the optical axis, an optical detector for detecting the intensity of the returning illumination light reflected by the sample and collected by the objective lens, and a controller for determining the operation amount of the angle adjustment mirror, wherein the controller determines the operation amount of the angle adjustment mirror so that the illumination light is totally reflected at the sample based on the change in intensity of the returning light when the angle adjustment mirror is changed.
    Type: Grant
    Filed: February 21, 2019
    Date of Patent: October 20, 2020
    Assignee: NIKON CORPORATION
    Inventors: Takayuki Morita, Akitoshi Suzuki, Tomoko Kobayashi, Keita Masuda
  • Patent number: 10654605
    Abstract: A packing apparatus includes a sealing mechanism, a timing sensing section, and a control section. The sealing mechanism affixes tape continuously on portions of a cardboard box transported with major flaps thereof folded. The sealing mechanism includes an affixing roller to press the tape against a first side surface and the major flaps. The timing sensing section senses the timing at which the affixing of the tape on the first side surface is initiated. The control section controls pressing force exerted by the affixing roller, based on a result of the sensing performed by the timing sensing section, in such a way that the pressing force is reduced after the affixing of the tape on the first side surface is initiated.
    Type: Grant
    Filed: October 14, 2015
    Date of Patent: May 19, 2020
    Assignee: ISHIDA CO., LTD.
    Inventors: Atsushi Takahashi, Yuji Yokota, Yoshinobu Shimomae, Tomoko Kobayashi
  • Publication number: 20190187449
    Abstract: The total internal reflection microscope has an illumination optical system that relays light from a light source with a relay optical system, forms an image of the light source on the incident pupil plane of the objective lens and irradiates a sample with the illumination light via an objective lens, has an angle adjustment mirror for changing the position of the image of the light source in a direction orthogonal to the optical axis, an optical detector for detecting the intensity of the returning illumination light reflected by the sample and collected by the objective lens, and a controller for determining the operation amount of the angle adjustment mirror, wherein the controller determines the operation amount of the angle adjustment mirror so that the illumination light is totally reflected at the sample based on the change in intensity of the returning light when the angle adjustment mirror is changed.
    Type: Application
    Filed: February 21, 2019
    Publication date: June 20, 2019
    Applicant: NIKON CORPORATION
    Inventors: Takayuki MORITA, Akitoshi SUZUKI, Tomoko KOBAYASHI, Keita MASUDA
  • Patent number: 10241312
    Abstract: The total internal reflection microscope has an illumination optical system that relays light from a light source with a relay optical system, forms an image of the light source on the incident pupil plane of the objective lens and irradiates a sample with the illumination light via an objective lens, has an angle adjustment mirror for changing the position of the image of the light source in a direction orthogonal to the optical axis, an optical detector for detecting the intensity of the returning illumination light reflected by the sample and collected by the objective lens, and a controller for determining the operation amount of the angle adjustment mirror, wherein the controller determines the operation amount of the angle adjustment mirror so that the illumination light is totally reflected at the sample based on the change in intensity of the returning light when the angle adjustment mirror is changed.
    Type: Grant
    Filed: April 29, 2016
    Date of Patent: March 26, 2019
    Assignee: NIKON CORPORATION
    Inventors: Takayuki Morita, Akitoshi Suzuki, Tomoko Kobayashi, Keita Masuda
  • Publication number: 20180022492
    Abstract: A packing apparatus includes a sealing mechanism, a timing sensing section, and a control section. The sealing mechanism affixes tape continuously on portions of a cardboard box transported with major flaps thereof folded. The sealing mechanism includes an affixing roller to press the tape against a first side surface and the major flaps. The timing sensing section senses the timing at which the affixing of the tape on the first side surface is initiated. The control section controls pressing force exerted by the affixing roller, based on a result of the sensing performed by the timing sensing section, in such a way that the pressing force is reduced after the affixing of the tape on the first side surface is initiated.
    Type: Application
    Filed: October 14, 2015
    Publication date: January 25, 2018
    Inventors: Atsushi TAKAHASHI, Yuji YOKOTA, Yoshinobu SHIMOMAE, Tomoko KOBAYASHI
  • Patent number: 9516209
    Abstract: An imaging apparatus includes an imaging unit for capturing a subject and generating image data of the subject, an operation input unit for receiving inputs of operation signals containing a release signal for instructing the imaging unit to shoot, an acceleration detector for detecting an acceleration of the imaging apparatus, a state detector for separately detecting a case in which the imaging apparatus is overland, a case in which the imaging apparatus is underwater and a photographer shoots while swimming, and a case in which the imaging apparatus is underwater and the photographer shoots while changing a water depth, and a control unit for performing operation control depending on an input into the operation input unit and/or into the acceleration detector according to a state detection result by the state detector.
    Type: Grant
    Filed: February 3, 2014
    Date of Patent: December 6, 2016
    Assignee: Olympus Corporation
    Inventors: Yuko Watanabe, Yoko Saito, Tomoko Kobayashi, Koichi Shintani
  • Publication number: 20160246043
    Abstract: The total internal reflection microscope has an illumination optical system that relays light from a light source with a relay optical system, forms an image of the light source on the incident pupil plane of the objective lens and irradiates a sample with the illumination light via an objective lens, has an angle adjustment mirror for changing the position of the image of the light source in a direction orthogonal to the optical axis, an optical detector for detecting the intensity of the returning illumination light reflected by the sample and collected by the objective lens, and a controller for determining the operation amount of the angle adjustment mirror, wherein the controller determines the operation amount of the angle adjustment mirror so that the illumination light is totally reflected at the sample based on the change in intensity of the returning light when the angle adjustment mirror is changed.
    Type: Application
    Filed: April 29, 2016
    Publication date: August 25, 2016
    Applicant: NIKON CORPORATION
    Inventors: Takayuki MORITA, Akitoshi SUZUKI, Tomoko KOBAYASHI, Keita MASUDA
  • Publication number: 20140210985
    Abstract: An imaging apparatus includes an imaging unit for capturing a subject and generating image data of the subject, an operation input unit for receiving inputs of operation signals containing a release signal for instructing the imaging unit to shoot, an acceleration detector for detecting an acceleration of the imaging apparatus, a state detector for separately detecting a case in which the imaging apparatus is overland, a case in which the imaging apparatus is underwater and a photographer shoots while swimming, and a case in which the imaging apparatus is underwater and the photographer shoots while changing a water depth, and a control unit for performing operation control depending on an input into the operation input unit and/or into the acceleration detector according to a state detection result by the state detector.
    Type: Application
    Filed: February 3, 2014
    Publication date: July 31, 2014
    Applicant: Olympus Imaging Corp.
    Inventors: Yuko WATANABE, Yoko SAITO, Tomoko KOBAYASHI, Koichi SHINTANI
  • Patent number: 8643713
    Abstract: An imaging apparatus includes an imaging unit for capturing a subject and generating image data of the subject, an operation input unit for receiving inputs of operation signals containing a release signal for instructing the imaging unit to shoot, an acceleration detector for detecting an acceleration of the imaging apparatus, a state detector for separately detecting a case in which the imaging apparatus is overland, a case in which the imaging apparatus is underwater and a photographer shoots while swimming, and a case in which the imaging apparatus is underwater and the photographer shoots while changing a water depth, and a control unit for performing operation control depending on an input into the operation input unit and/or into the acceleration detector according to a state detection result by the state detector.
    Type: Grant
    Filed: August 9, 2013
    Date of Patent: February 4, 2014
    Assignee: Olympus Imaging Corp.
    Inventors: Yuko Watanabe, Yoko Saito, Tomoko Kobayashi, Koichi Shintani
  • Publication number: 20130321611
    Abstract: An imaging apparatus includes an imaging unit for capturing a subject and generating image data of the subject, an operation input unit for receiving inputs of operation signals containing a release signal for instructing the imaging unit to shoot, an acceleration detector for detecting an acceleration of the imaging apparatus, a state detector for separately detecting a case in which the imaging apparatus is overland, a case in which the imaging apparatus is underwater and a photographer shoots while swimming, and a case in which the imaging apparatus is underwater and the photographer shoots while changing a water depth, and a control unit for performing operation control depending on an input into the operation input unit and/or into the acceleration detector according to a state detection result by the state detector.
    Type: Application
    Filed: August 9, 2013
    Publication date: December 5, 2013
    Applicant: Olympus Imaging Corp.
    Inventors: Yuko WATANABE, Yoko SAITO, Tomoko KOBAYASHI, Koichi SHINTANI
  • Patent number: 8531515
    Abstract: An imaging apparatus includes an imaging unit for capturing a subject and generating image data of the subject, an operation input unit for receiving inputs of operation signals containing a release signal for instructing the imaging unit to shoot, an acceleration detector for detecting an acceleration of the imaging apparatus, a state detector for separately detecting a case in which the imaging apparatus is overland, a case in which the imaging apparatus is underwater and a photographer shoots while swimming, and a case in which the imaging apparatus is underwater and the photographer shoots while changing a water depth, and a control unit for performing operation control depending on an input into the operation input unit and/or into the acceleration detector according to a state detection result by the state detector.
    Type: Grant
    Filed: September 27, 2010
    Date of Patent: September 10, 2013
    Assignee: Olympus Imaging Corp.
    Inventors: Yuko Watanabe, Yoko Saito, Tomoko Kobayashi, Koichi Shintani
  • Publication number: 20110074945
    Abstract: An imaging apparatus includes an imaging unit for capturing a subject and generating image data of the subject, an operation input unit for receiving inputs of operation signals containing a release signal for instructing the imaging unit to shoot, an acceleration detector for detecting an acceleration of the imaging apparatus, a state detector for separately detecting a case in which the imaging apparatus is overland, a case in which the imaging apparatus is underwater and a photographer shoots while swimming, and a case in which the imaging apparatus is underwater and the photographer shoots while changing a water depth, and a control unit for performing operation control depending on an input into the operation input unit and/or into the acceleration detector according to a state detection result by the state detector.
    Type: Application
    Filed: September 27, 2010
    Publication date: March 31, 2011
    Inventors: Yuko Watanabe, Yoko Saito, Tomoko Kobayashi, Koichi Shintani
  • Patent number: 5800982
    Abstract: The present invention relates to an NS4-related antigenic peptide capable of reacting specifically with antibodies directed against Group I of hepatitis C virus (HCV); to an NS4-related antigenic peptide capable of reacting specifically with antibodies directed against Group II of HCV; to a kit for identifying HCV Groups I or II which comprises said peptides in separate sections; and to methods for grouping HCV. The peptides of the present invention can be used to detect HCV Groups I or II specifically as well as the detection of patients having the mixed infection, by which HCV Group II-infected patients can receive early interferon treatment effectively. The peptides are also useful for diagnosis of HCV infection.
    Type: Grant
    Filed: July 24, 1996
    Date of Patent: September 1, 1998
    Assignee: Tonen Corporation
    Inventors: Akira Hasegawa, Noboru Maki, Shintaro Yagi, Tomiko Kashiwakuma, Kenjiro Yamaguchi, Naoko Ikeguchi, Tomoko Kobayashi, Chiaki Senoo
  • Patent number: 5762929
    Abstract: The present invention relates to an novel anti-motoneuron-disease agent, comprising superoxide dismutase conjugated with lecithin through chemical crosslinking represented in the following generic formula (PC-SOD) as an effective ingredient:SOD--?C(O)--(CH.sub.2).sub.n --C(O)--X!.sub.mwherein SOD represents superoxide dismutase and X represents a residue of lysolecithin having a hydroxy group at position 2 of glycerol whose hydrogen atom of the hydroxyl group at position 2 is removed.A pharmaceutical agent of the present invention may improve symptoms of motoneuron diseases such as amyotrophic lateral sclerosis etc. by oral or parenteral administration. The present invention also relates to a novel treatment method for motoneuron disease by administrating PC-SOD and novel use of PC-SOD as a medical composition for preparing an agent for treating motoneuron disease.
    Type: Grant
    Filed: July 31, 1995
    Date of Patent: June 9, 1998
    Assignee: SAM Research Corporation
    Inventors: Masao Kinoshita, Yasuo Iwasaki, Ken Ikeda, Toshiya Shiojima, Nozomu Tagaya, Tomoko Kobayashi