Patents by Inventor Tomoko Komiyama

Tomoko Komiyama has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Eglin c based drugs for treatment of disease
    Patent number: 7001884
    Abstract: The present invention relates to eglin c variants which inhibit proteases, and in particular to eglin c mutants at adventitious contact sites. The present invention also relates to eglin c variants which comprise mutations in both adventitious contact sites and at reactive loop sites. The present invention further relates to methods of preparing the eglin c variants, and methods of using the eglin c variants for treatment of diseases including acute bacterial, viral, and fungal infections.
    Type: Grant
    Filed: June 17, 2002
    Date of Patent: February 21, 2006
    Assignee: Regents of the University of Michigan
    Inventors: Tomoko Komiyama, Robert S. Fuller
  • EGLIN C BASED DRUGS FOR TREATMENT OF DISEASE
    Publication number: 20050203007
    Abstract: The present invention relates to eglin c variants which inhibit proteases, and in particular to eglin c mutants at adventitious contact sites. The present invention also relates to eglin c variants which comprise mutations in both adventitious contact sites and at reactive loop sites. The present invention further relates to methods of preparing the eglin c variants, and methods of using the eglin c variants for treatment of diseases including acute bacterial, viral, and fungal infections.
    Type: Application
    Filed: June 17, 2002
    Publication date: September 15, 2005
    Inventors: Tomoko Komiyama, Robert Fuller
  • Novel protein, process for producing the same and use therof
    Publication number: 20030125253
    Abstract: The present invention relates to a novel SSD(sterol-sensing domain)-containing protein derived from human liver, human testis and human brain, or a salt thereof, and a DNA encoding the same. Studies on the tissue-specificity of the protein expression, the expression change depending the intracellular cholesterol level, production of the transformant, and the site-specific expression in brain regions of a patient with Alzheimer's disease are disclosed.
    Type: Application
    Filed: September 19, 2002
    Publication date: July 3, 2003
    Inventors: Yoshio Taniyama, Shunbun Kita, Tomoko Satomi nee Tomoko Komiyama