Abstract: A network management system includes a plurality of server units. A first management server included in a first server unit transmits a disconnection setting request for disconnecting an abnormal flow to each of a communication node connected to a self-region covered by the first management server, and one or more second server units covering one or more primary adjacent regions adjacent to the self-region. Disconnection setting is executed in response to the disconnection setting request. Each of a plurality of regions includes two or more areas each of which is covered by corresponding one of two or more base stations connected to an identical communication node.

Abstract: A network management system includes a plurality of server units. A first management server included in a first server unit transmits a disconnection setting request for disconnecting an abnormal flow to each of a communication node connected to a self-region covered by the first management server, and one or more second server units covering one or more primary adjacent regions adjacent to the self-region. Disconnection setting is executed in response to the disconnection setting request. Each of a plurality of regions includes two or more areas each of which is covered by corresponding one of two or more base stations connected to an identical communication node.

Abstract: An object of the present invention is to provide an activated blood coagulation factor X (FXa) inhibitor that reduces the risk of bleeding caused by the treatment of thromboembolism. The present invention provides an oral anticoagulant agent comprising a compound represented by the following formula (1): or a pharmacologically acceptable salt thereof, or a hydrate thereof, as an active ingredient, wherein (A) a factor involved in the risk of bleeding caused by the anticoagulant agent is selected as a dose determinant; (B) a reference value of the dose determinant is set; (C) the dose determinant of a patient in need of administration is measured; and (D) the dose of the anticoagulant agent is selected with the reference value as an index.