Patents by Inventor Tomoko Ohyama

Tomoko Ohyama has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11060081
    Abstract: Disclosed is a specimen pretreatment apparatus comprising: a specimen container holder configured to hold a specimen container for containing a plasma specimen; a reagent container holder configured to hold a first reagent container for containing a first reagent including magnetic particles on which a nucleic acid in the plasma specimen is adsorbed; a reaction unit in which a plurality of reaction containers are disposed, the reaction unit being configured to accelerate, in each reaction container, reaction of the plasma specimen and the first reagent; a washing unit in which a washing container is disposed, the washing unit including a magnetic force applying portion configured to apply magnetic force to the washing container; a dispensing unit; and a controller programmed to control the dispensing unit to: dispense the plasma specimen contained in the specimen container and the first reagent into the plurality of reaction containers in the reaction unit; dispense a mix liquid of the plasma specimen and the
    Type: Grant
    Filed: February 27, 2017
    Date of Patent: July 13, 2021
    Assignee: SYSMEX CORPORATION
    Inventors: Yasuhiro Sakai, Hiroaki Tobimatsu, Takeo Saitou, Tomoko Ohyama, Takanori Maekawa
  • Publication number: 20200043595
    Abstract: A computer-implemented method according to one or more aspects may include: analyzing action-related information on an action of a user to prepare an analysis result; and generating advice information concerning improvement of a daily habit of the user based on: the analysis result; and a piece of management policy information corresponding to a type of advice requested by the user among pieces of management policy information.
    Type: Application
    Filed: July 29, 2019
    Publication date: February 6, 2020
    Applicant: SYSMEX CORPORATION
    Inventors: Tomoko OHYAMA, Hiromi YOSHINARI, Yuuki WATANABE, Koji IKEDA, Kenichiro SUZUKI
  • Publication number: 20170247682
    Abstract: Disclosed is a specimen pretreatment apparatus comprising: a specimen container holder configured to hold a specimen container for containing a plasma specimen; a reagent container holder configured to hold a first reagent container for containing a first reagent including magnetic particles on which a nucleic acid in the plasma specimen is adsorbed; a reaction unit in which a plurality of reaction containers are disposed, the reaction unit being configured to accelerate, in each reaction container, reaction of the plasma specimen and the first reagent; a washing unit in which a washing container is disposed, the washing unit including a magnetic force applying portion configured to apply magnetic force to the washing container; a dispensing unit; and a controller programmed to control the dispensing unit to: dispense the plasma specimen contained in the specimen container and the first reagent into the plurality of reaction containers in the reaction unit; dispense a mix liquid of the plasma specimen and the
    Type: Application
    Filed: February 27, 2017
    Publication date: August 31, 2017
    Inventors: Yasuhiro SAKAI, Hiroaki TOBIMATSU, Takeo SAITOU, Tomoko OHYAMA, Takanori MAEKAWA
  • Publication number: 20120278000
    Abstract: A method for assessing an efficacy of combination chemotherapy, comprising: a first obtaining process for obtaining a specific activity value of Cyclin Dependent Kinase (CDK) 1 and a specific activity value of CDK2 in a biological sample including a carcinoma cell collected from a cancer patient; a second obtaining process for obtaining a GST? expression level in the biological sample; and an assessment process for assessing the efficacy of the combination chemotherapy on the cancer patient based on the specific activity values of CDK1 and CDK2 obtained in the first obtaining process and the GST? expression level obtained in the second obtaining process.
    Type: Application
    Filed: April 26, 2012
    Publication date: November 1, 2012
    Applicant: SYSMEX CORPORATION
    Inventors: Chihiro SUMINAKA, Amame HARADA, Tomoko OHYAMA, Yasuhiro TORIKOSHI
  • Publication number: 20110244497
    Abstract: The present invention provides a method for judging susceptibility of cancer cells contained in a biological sample to an anthracycline anticancer agent comprising steps of: measuring expression levels of GST-? of cancer cells contained in a biological sample; and judging the susceptibility of cancer cells contained in a biological sample to an anthracycline anticancer agent as high when the expression level of GST-? obtained by the measuring process is high, and a computer program which makes a computer execute the method.
    Type: Application
    Filed: March 30, 2011
    Publication date: October 6, 2011
    Applicant: SYSMEX CORPORATION
    Inventors: Tomoko Ohyama, Masaki Shibayama, Hideki Ishihara, Tomokazu Yoshida, Keigo Gohda
  • Publication number: 20100250483
    Abstract: An effect predicting apparatus for predicting an effect of anthracycline anticancer drugs, comprising: a display, a processor, and a memory, under control of said processor, including software instructions adapted to enable the processor to perform operations, comprising: acquiring a CDK parameter based on a first CDK parameter and a second CDK parameter; acquiring an expression level of glutathione; comparing the CDK parameter with a CDK threshold value, and the expression level of glutathione with a glutathione threshold value; predicting an effect of anthracycline anticancer drugs based on the result of the comparison; and displaying the result of the prediction. A computer program product and a method for predicting an effect are also disclosed.
    Type: Application
    Filed: September 29, 2009
    Publication date: September 30, 2010
    Applicant: SYSMEX CORPORATION
    Inventors: Tomoko Ohyama, Masaki Shibayama, Hideki Ishihara, Tomokazu Yoshida, Keigo Gohda
  • Publication number: 20080090254
    Abstract: A method for assessing the proliferation inhibiting effect of a receptor tyrosine kinase inhibitor is described. In the method, a cytoplasm is separated from a tumor cell to prepare a sample containing various receptor tyrosine kinases. The prepared sample is treated with the inhibitor. The receptor tyrosine kinases in the treated sample, and a substrate for at least two kinds of receptor tyrosine kinases are contacted. The phosphorylated substrate is detected, and the activity value of the receptor tyrosine kinases is measured based on the detection result. The proliferation inhibiting effect is assessed based on the resulting activity value.
    Type: Application
    Filed: September 27, 2007
    Publication date: April 17, 2008
    Applicant: SYSMEX CORPORATION
    Inventors: Michitaka Notoya, Jun Sato, Tomoko Ohyama, Tomokazu Yoshida, Hideki Ishihara
  • Publication number: 20080003630
    Abstract: A tyrosine kinase substrate is described. The tyrosine kinase substrate comprises a fusion protein which comprises a protein for labeling and a specific peptide fused with the protein for labeling. The specific peptide has an amino acid sequence including a glutamic acid residue and a tyrosine residue. The tyrosine kinase substrate is capable of being phosphorylated by a plurality of kinds of tyrosine kinases.
    Type: Application
    Filed: June 26, 2007
    Publication date: January 3, 2008
    Applicant: SYSMEX CORPORATION
    Inventors: Michitaka Notoya, Tomoko Ohyama, Tomokazu Yoshida, Hideki Ishihara
  • Publication number: 20070238141
    Abstract: A method for measuring the activity of a receptor kinase present in a cell membrane of a cell is described. The method comprises steps of preparing a sample containing the receptor kinase by separating a cytoplasm from the cell, contacting the receptor kinase in the sample with a substrate to phosphorylate the substrate with the activity of the receptor kinase, binding a labeling substance to the phosphorylated substrate, and measuring the activity of the receptor kinase based on a result of detection of the labeling substance bound to the phosphorylated substrate.
    Type: Application
    Filed: March 30, 2007
    Publication date: October 11, 2007
    Applicant: SYSMEX CORPORATION
    Inventors: Michitaka Notoya, Tomoko Ohyama, Shigeyuki Tamura, Tomokazu Yoshida, Hideki Ishihara
  • Patent number: 5751373
    Abstract: A method and apparatus by which function as of a television receiver can be selected simply. A main menu displays the highest level of a hierarchical menu which includes items corresponding to functions of a television receiver is displayed on a left side portion of a screen of the television receiver. When a cursor is moved to the first item of the main menu, while the main menu remains displayed on the screen, a sub menu corresponding to the first item is displayed on a right side portion of the screen. When the cursor is subsequently moved to one of the items forming the sub menu and then a predetermined operation is performed.
    Type: Grant
    Filed: March 28, 1996
    Date of Patent: May 12, 1998
    Assignee: Sony Corporation
    Inventors: Tomoko Ohyama, Yukiko Ohkura, Masaharu Fukumoto, Shigeyuki Sano, Yasuko Rokukawa, Shiro Endo, Kyosuke Oda, Yumiko Minakawa, Chifumi Matsuura