Abstract: A topsheet for body fluids absorbent article is made of thermoplastic synthetic fibers mechanically entangled so as to extend substantially in a desired one direction and formed with liquid-permeable openings. The openings comprise a first group of openings each having a substantially oval shape defined by its major axis extending substantially in parallel to the direction in which the fibers extend and its minor axis extending orthogonally to the major axis and a second group of openings each having a substantially oval shape defined by its minor axis extending substantially in parallel to the direction in which the fibers 11 extend and its major axis extending orthogonally to the minor axis.

Abstract: A liquid-permeable topsheet used in a disposable body fluids absorbent garment has planar portions substantially extending in a horizontal plane, a plurality of ribs rising from the planar portions and extending parallel one to another, each presenting a cross-section in an inverted v-shape, and liquid-passages extending downward from the planar portions and thereby eliminate any appreciation that eruption and/or stuffiness might be caused by contact of the topsheet with the skin of a wearer.

Abstract: A topsheet for body exudates absorbent article includes a hydrophilic nonwoven fibrous sheet and a plurality of thermoplastic synthetic resin filaments extending in one direction parallel to one another and continuously bonded to an upper surface of the nonwoven fibrous sheet so that a composite sheet of these sheet and filaments have crests and troughs alternately repeating longitudinally of the filaments and respectively extend transversely of the filaments. An apparatus and a method for manufcturing the topsheet are also disclosed, wherein a pair of mutually engageable embossing rolls are used for forming the crests and the troughs onto the coposite sheet.

Abstract: A body fluids absorbent article has a liquid-permeable topsheet formed by a nonwoven fabric of thermoplastic synthetic fibers. The topsheet is formed with a plurality of openings each having a diameter of 0.5.about.3 mm. These openings queue up so as to form plural columns of openings extending in parallel one to another. One half or more of a total number of the openings are reinforced by strands of thermoplastic synthetic resin each having a diameter of 0.1.about.0.5 mm and extending circumferentially of the respective openings.

Abstract: A topsheet used in a disposable body fluids absorbent garment comprises a plurality of first ribs extending in parallel one to another in one direction and a plurality of second ribs extending in parallel one to another so as to intersect the first ribs. Each pair of adjacent first ribs intersect each pair of adjacent second ribs to define an air- and moisture-permeably opened region around which at least one of the respective pairs of adjacent first ribs and adjacent second ribs have their crests configured so that, between each pair of adjacent intersections of the first and second ribs each of the crests underlies an imaginary straight line connecting this pair of adjacent intersections.

Abstract: Nerve growth factor production accelerating agents containing oxazopyrroloquinolines, pyrroquinolinequinones and/or their esters as active ingredient are provided. As the oxazopyrroloquinolines and their esters exhibit such production accelerating activity, they are suitably utilized for preventing and treating functional disorders of central nervous system, particularly, Alzheimer's dementia, cerebral ischemia and spinal trauma, as well as for functional disorders of peripheral nervous system, particularly, peripheral nervous system trauma and diabetic neurosis. As the pyrroquinolinequinones and their esters exhibit strong nerve growth factor production accelerating activity, they are suitably utilized for preventing and treating functional disorders of peripheral nervous system, particularly, peripheral nervous system trauma, diabetic neurosis, etc.

Abstract: A physiologically active polypeptide, BUF-3, having the ability to differentiate and maturate human leukemia cells into normal cells and of accelerating the formation of erythroblasts is disclosed. The polypeptide has a molecular weight of 16.+-.1 Kd as determined by SDS-electrophoresis in the presence of 1% mercaptoethanol, or 25.+-.1 Kd, as determined by SDS-electrophoresis in the absence of mercaptoethanol.

Abstract: The liquid-permeable composite nonwoven fabric for use in the body fluids absorptive articles such as sanitary napkins comprises a liquid-permeable nonwoven fabric made from thermoplastic synthetic fibres and a plurality of continuous filaments made from thermoplastic synthetic resin being arranged parallel to one another and bonded to an upper surface of the nonwoven fabric at bonding zones arranged intermittently along and longitudinally of the respective filaments so that each filament may form bulges describing circular arcs above the nonwoven fabric.

Abstract: A disposable absorbent article 1 comprising a liquid-absorbent core at least an upper surface of which is covered with a topsheet provided with a plurality of liquid guide passages, a body fluid diffusing sheet made of hydrophilic fibers being disposed between a lower surface of the topsheet and the upper surface of the liquid-absorbent core, the sheet being formed on its upper surface with a plurality of parallel extending stripe-zones of a hydrophobic synthetic resin.

Abstract: Nerve growth factor production accelerating agents containing oxazopyrroloquinolines, pyrroquinolinequinones and/or their esters as active ingredient are provided. As the oxazopyrroloquinolines and their esters exhibit such production accelerating activity, they are suitably utilized for preventing and treating functional disorders of central nervous system, particularly, Alzheimer's dementia, cerebral ischemia and spinal trauma, as well as for functional disorders of Peripheral nervous system, particularly, peripheral nervous system trauma and diabetic neurosis. As the pyrroquinolineguinones and their esters exhibit strong nerve growth factor production accelerating activity, they are suitably utilized for preventing and treating functional disorders of peripheral nervous system, particularly, peripheral nervous system trauma, diabetic neuropathy, etc.