Patents by Inventor Tomomasa Shimanuki

Tomomasa Shimanuki has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method of identifying abnormal cells by expression levels of ETFB
    Patent number: 9562912
    Abstract: Provided is a method for identifying and suppressing abnormal growth of fibroblasts at an early stage. Provided is a method for identifying the growth state of fibroblasts using as an index the level of expression of ETFB (electron transfer flavoprotein beta subunit), comprising: judging, in cases where the level of expression of ETFB is high, that there is a high probability that fibroblasts are abnormally growing; and judging, in cases where the level of expression of ETFB is low, that there is a high probability that fibroblasts are normally growing. Further, by inhibition of ETFB, abnormal growth of fibroblasts can be suppressed.
    Type: Grant
    Filed: December 27, 2011
    Date of Patent: February 7, 2017
    Assignee: POLA PHARMA INC.
    Inventors: Shigenari Hirokawa, Hiroyuki Kitajima, Tomomasa Shimanuki
  • METHOD OF APPLYING ETFB TO ABNORMAL PROLIFERATION OF CELL, AND ABNORMAL PROLIFERATION INHIBITOR
    Publication number: 20140235491
    Abstract: Provided is a method for identifying and suppressing abnormal growth of fibroblasts at an early stage. Provided is a method for identifying the growth state of fibroblasts using as an index the level of expression of ETFB (electron transfer flavoprotein beta subunit), comprising: judging, in cases where the level of expression of ETFB is high, that there is a high probability that fibroblasts are abnormally growing; and judging, in cases where the level of expression of ETFB is low, that there is a high probability that fibroblasts are normally growing. Further, by inhibition of ETFB, abnormal growth of fibroblasts can be suppressed.
    Type: Application
    Filed: December 27, 2011
    Publication date: August 21, 2014
    Applicant: POLA PHARMA INC.
    Inventors: Shigenari Hirokawa, Hiroyuki Kitajima, Tomomasa Shimanuki
  • Benzofuran derivatives and pharmaceutical compositions containing the same
    Patent number: 6797711
    Abstract: Benzofuran derivatives represented by formula (I) or salts thereof: (wherein R1 represents a phenyl group or a hydrogen atom; k is 0 or 1; each of m, n, o, p, and q is an integer of 0 to 5; and each of R2 and R3 represents a hydrogen atom or a hydroxyl group, or R2 and R3 together represent an oxygen atom, with proviso that k, q, and m, or n, o, and p are not simultaneously 0). The compounds inhibit phosphorylation of STAT 6 and are useful in the treatment or prevention of allergic diseases.
    Type: Grant
    Filed: June 26, 2003
    Date of Patent: September 28, 2004
    Assignee: Pola Chemical Industries, Inc.
    Inventors: Nobuyuki Kawakatsu, Takayuki Namiki, Norihisa Yamazaki, Masayuki Yuasa, Toyohiko Miki, Noriko Suenobu, Tomomasa Shimanuki
  • Benzofuran derivatives and pharmaceutical compositions containing the same
    Publication number: 20040053940
    Abstract: Benzofuran derivatives represented by formula (I) or salts thereof: 1
    Type: Application
    Filed: June 26, 2003
    Publication date: March 18, 2004
    Inventors: Nobuyuki Kawakatsu, Takayuki Namiki, Norihisa Yamazaki, Masayuki Yuasa, Toyohiko Miki, Noriko Suenobu, Tomomasa Shimanuki