Patents by Inventor Tomomi Sotome

Tomomi Sotome has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Inhibitors against the production and release of inflammatory cytokines
    Patent number: 8263657
    Abstract: A medicament having inhibitory activity against NF-?B activation, which comprises a compound represented by the following general formula (I) or a pharmacologically acceptable salt as an active ingredient: wherein X represents a connecting group, A represents hydrogen atom or acetyl group, E represents an aryl group or a heteroaryl group, and ring X represents an arene or a heteroarene.
    Type: Grant
    Filed: December 18, 2001
    Date of Patent: September 11, 2012
    Assignee: Institute of Medicinal Molecular Design, Inc.
    Inventors: Susumu Muto, Tatsuo Nagano, Tomomi Sotome, Akiko Itai
  • Inflammatory cytokine release inhibitor
    Patent number: 8097759
    Abstract: A medicament having inhibitory activity against NF-?B activation, which comprises a compound represented by the following general formula (I) or a pharmacologically acceptable salt as an active ingredient: wherein X represents a connecting group, A represents hydrogen atom or acetyl group, E represents an aryl group or a heteroaryl group, and ring X represents an arene or a heteroarene.
    Type: Grant
    Filed: July 2, 2010
    Date of Patent: January 17, 2012
    Assignee: Institute of Medicinal Molecular Design, Inc.
    Inventors: Susumu Muto, Tatsuo Nagano, Tomomi Sotome, Akiko Itai
  • INFLAMMATORY CYTOKINE RELEASE INHIBITOR
    Publication number: 20100274051
    Abstract: A medicament having inhibitory activity against NF-?B activation, which comprises a compound represented by the following general formula (I) or ? pharmacologically acceptable salt as an active ingredient: wherein X represents a connecting group, A represents hydrogen atom or acetyl group, E represents an aryl group or a heteroaryl group, and ring X represents an arene or a heteroarene.
    Type: Application
    Filed: July 2, 2010
    Publication date: October 28, 2010
    Applicant: Institute of Medicinal Molecular Design. Inc.
    Inventors: Susumu MUTO, Tatsuo Nagano, Tomomi Sotome, Akiko Itai
  • INFLAMMATORY CYTOKINE RELEASE INHIBITOR
    Publication number: 20090192122
    Abstract: A medicament having inhibitory activity against NF-?B activation, which comprises a compound represented by the following general formula (I) or a pharmacologically acceptable salt as an active ingredient: wherein X represents a connecting group, A represents hydrogen atom or acetyl group, E represents an aryl group or a heteroaryl group, and ring X represents an arene or a heteroarene.
    Type: Application
    Filed: August 8, 2007
    Publication date: July 30, 2009
    Applicant: INSTITUTE OF MEDICINAL MOLECULAR DESIGN, INC.
    Inventors: Susumu MUTO, Tatsuo NAGANO, Tomomi SOTOME, Akiko ITAI
  • INFLAMMATORY CYTOKINE RELEASE INHIBITOR
    Publication number: 20080318956
    Abstract: A medicament having inhibitory activity against NF-?B activation, which comprises a compound represented by the following general formula (I) or a pharmacologically acceptable salt as an active ingredient: wherein X represents a connecting group, A represents hydrogen atom or acetyl group, E represents an aryl group or a heteroaryl group, and ring X represents an arene or a heteroarene.
    Type: Application
    Filed: August 8, 2007
    Publication date: December 25, 2008
    Applicant: INSTITUTE OF MEDICINAL MOLECULAR DESIGN. INC.
    Inventors: Susumu MUTO, Tatsuo NAGANO, Tomomi SOTOME, Akiko ITAI
  • INFLAMMATORY CYTOKINE RELEASE INHIBITOR
    Publication number: 20080249071
    Abstract: A medicament having inhibitory activity against NF-?B activation, which comprises a compound represented by the following general formula (I) or a pharmacologically acceptable salt as an active ingredient: wherein X represents a connecting group, A represents hydrogen atom or acetyl group, E represents an aryl group or a heteroaryl group, and ring X represents an arene or a heteroarene.
    Type: Application
    Filed: August 8, 2007
    Publication date: October 9, 2008
    Applicant: INSTITUTE OF MEDICINAL MOLECULAR DESIGN. INC.
    Inventors: Susumu MUTO, Tatsuo NAGANO, Tomomi SOTOME, Akiko ITAI
  • Plasminogen Activator Inhibitor-1 Inhibitor
    Publication number: 20070276011
    Abstract: A medicament having inhibitory activity against plasminogen activator inhibitor-1, which comprises as an active ingredient a compound represented by the following general formula (I) or a salt thereof: wherein R1 and R2 represents an aromatic group which may be substituted, W represents a group selected from the following connecting group W-1: (wherein a bond at the left end binds to the carbon atom and a bond at the right end binds to the nitrogen atom, X represents sulfur atom or NH, Y represents oxygen atom or sulfur atom, R3 represents a hydrocarbon group, hydroxy group, or carboxy group), Z represents a single bond or a connecting group wherein a number of atoms in a main chain is 1 to 3.
    Type: Application
    Filed: September 3, 2004
    Publication date: November 29, 2007
    Inventors: Susumu Muto, Asako Kubo, Akiko Itai, Tomomi Sotome, Yoichi Yamaguchi
  • Inhibitors against the production and release of inflammatory cytokines
    Publication number: 20040259877
    Abstract: A medicament having inhibitory activity against NF-&kgr;B activation, which comprises a compound represented by the following general formula (I) or a pharmacologically acceptable salt as an active ingredient: 1
    Type: Application
    Filed: February 19, 2004
    Publication date: December 23, 2004
    Inventors: Susumu Muto, Tatsuo Nagano, Tomomi Sotome, Akiko Itai