Abstract: Provided is a method for producing a decorative material, including: a preparation step of preparing sheet printed matters each including a substrate and a picture layer on one surface of the substrate and a roll of a transparent resin film having a first surface and a second surface opposing to each other, the first surface having a pattern of protrusions and depressions, the second surface having a pattern of protrusions and depressions that is shallower than the pattern of protrusions and depressions on the first surface; an application step of winding off the transparent resin film from the roll of a transparent resin film and applying an adhesive to the second surface of the transparent resin film; and a bonding step of bonding the second surface of the transparent resin film and the picture layer of each of the sheet printed matters with the adhesive.

Abstract: Antibodies (Abs) play roles in protection against influenza. Neutralizing Abs either inhibit the binding of hemagglutinin (HA) to cellular receptors or prevent the conformational change of HA induced by low pH. The former Ab binds to the regions near the sialic acid-binding pocket on the globular head formed by HA1 and generally shows narrow strain specificity. The latter Ab binds to the stem region formed mainly by HA2 and shows broad strain specificity. We isolated a broadly neutralizing Ab against H3N2 viruses. X-ray analysis of the HA/Ab complex indicated that the Ab binds to the valley formed by two neighboring HA monomers at the side of the globular head. The Ab shows neutralizing activity by preventing the conformational change of HA induced at low pH.