Patents by Inventor Tomonobu MUTSUMI

Tomonobu MUTSUMI has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Stable crystal form of tipiracil hydrochloride and crystallization method for the same
    Patent number: 10457666
    Abstract: Crystal Form I of 5-chloro-6-(2-iminopyrrolidin-1-yl)methyl-2,4(1H,3H)-pyrimidinedione hydrochloride exhibiting powder X-ray peaks at two or more angles selected from the group consisting of 11.6°, 17.2°, 17.8°, 23.3°, 27.1°, and 29.3° as a diffraction angle (2?±0.2°).
    Type: Grant
    Filed: May 2, 2018
    Date of Patent: October 29, 2019
    Assignee: TAIHO PHARMACEUTICAL CO., LTD.
    Inventors: Hideki Kazuno, Tomonobu Mutsumi
  • Stable crystal form of tipiracil hydrochloride and crystallization method for the same
    Patent number: 10138223
    Abstract: An objective of the present invention is to obtain a stable crystal form of 5-chloro-6-(2-iminopyrrolidin-1-yl)methyl-2,4 (1H,3H)-pyrimidinedione hydrochloride. The present invention provides a crystal of 5-chloro-6-(2-iminopyrrolidin-1-yl)methyl-2,4 (1H,3H)-pyrimidinedione hydrochloride exhibiting characteristic peaks at angles of 11.6°, 17.2°, 17.8°, 23.3°, 27.1°, and 29.3° as a diffraction angle (2?±0.1°) in powder X-ray diffraction.
    Type: Grant
    Filed: November 16, 2016
    Date of Patent: November 27, 2018
    Assignee: TAIHO PHARMACEUTICALS CO., LTD.
    Inventors: Hideki Kazuno, Tomonobu Mutsumi
  • STABLE CRYSTAL FORM OF TIPIRACIL HYDROCHLORIDE AND CRYSTALLIZATION METHOD FOR THE SAME
    Publication number: 20180291005
    Abstract: Crystal Form I of 5-chloro-6-(2-iminopyrrolidin-1-yl)methyl-2,4(1H,3H)-pyrimidinedione hydrochloride exhibiting powder X-ray peaks at two or more angles selected from the group consisting of 11.6°, 17.2°, 17.8°, 23.3°, 27.1°, and 29.3° as a diffraction angle (2?±0.2°).
    Type: Application
    Filed: May 2, 2018
    Publication date: October 11, 2018
    Applicant: TAIHO PHARMACEUTICAL CO., LTD.
    Inventors: Hideki KAZUNO, Tomonobu MUTSUMI
  • STABLE CRYSTAL FORM OF TIPIRACIL HYDROCHLORIDE AND CRYSTALLIZATION METHOD FOR THE SAME
    Publication number: 20170057949
    Abstract: An objective of the present invention is to obtain a stable crystal form of 5-chloro-6-(2-iminopyrrolidin-1-yl)methyl-2,4 (1H,3H)-pyrimidinedione hydrochloride. The present invention provides a crystal of 5-chloro-6-(2-iminopyrrolidin-1-yl)methyl-2,4 (1H,3H)-pyrimidinedione hydrochloride exhibiting characteristic peaks at angles of 11.6°, 17.2°, 17.8°, 23.3°, 27.1°, and 29.3° as a diffraction angle (2?±0.1°) in powder X-ray diffraction.
    Type: Application
    Filed: November 16, 2016
    Publication date: March 2, 2017
    Applicant: TAIHO PHARMACEUTICAL CO., LTD.
    Inventors: Hideki KAZUNO, Tomonobu MUTSUMI
  • Stable crystal form of tipiracil hydrochloride and crystallization method for the same
    Patent number: 9527833
    Abstract: An objective of the present invention is to obtain a stable crystal form of 5-chloro-6-(2-iminopyrrolidin-1-yl)methyl-2,4(1H,3H)-pyrimidinedione hydrochloride. The present invention provides a crystal of 5-chloro-6-(2-iminopyrrolidin-1-yl)methyl-2,4(1H,3H)-pyrimidinedione hydrochloride exhibiting characteristic peaks at angles of 11.6°, 17.2°, 17.8°, 23.3°, 27.1°, and 29.3° as a diffraction angle (2?±0.1°) in powder X-ray diffraction.
    Type: Grant
    Filed: June 17, 2014
    Date of Patent: December 27, 2016
    Assignee: TAIHO PHARMACEUTICAL CO., LTD.
    Inventors: Hideki Kazuno, Tomonobu Mutsumi
  • STABLE CRYSTAL FORM OF TIPIRACIL HYDROCHLORIDE AND CRYSTALLIZATION METHOD FOR THE SAME
    Publication number: 20160145241
    Abstract: An objective of the present invention is to obtain a stable crystal form of 5-chloro-6-(2-iminopyrrolidin-1-yl)methyl-2,4(1H,3H)-pyrimidinedione hydrochloride. The present invention provides a crystal of 5-chloro-6-(2-iminopyrrolidin-1-yl)methyl-2,4(1H,3H)-pyrimidinedione hydrochloride exhibiting characteristic peaks at angles of 11.6°, 17.2°, 17.8°, 23.3°, 27.1°, and 29.3° as a diffraction angle (2?±0.1°) in powder X-ray diffraction.
    Type: Application
    Filed: June 17, 2014
    Publication date: May 26, 2016
    Applicant: TAIHO PHARMACEUTICAL CO., LTD.
    Inventors: Hideki KAZUNO, Tomonobu MUTSUMI